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NCT ID: NCT04498533 Completed - Clinical trials for Lateral Epicondylitis (Tennis Elbow)

Bracing or Kinesio Taping in The Management of Lateral Epicondylitis

Start date: June 1, 2014
Phase: N/A
Study type: Interventional

Lateral epicondylitis is an overuse syndrome of the forearm, which is associated with pain and sensitivity in the lateral elbow region. The aim of the study was to find out about is there any difference between the effects of traditional orthotic devices and adhesive taping, in the management of lateral epicondylitis. Therefore, the forearm counterforce brace, which was widely used in daily clinical practice for lateral epicondylitis, was compared with kinesio tape, a new technique of adhesive taping which has become increasingly popular. The study investigated and compared the effects of the two interventions (the forearm counterforce brace and kinesio tape) on pain severity, functional status and disability of patients with lateral epicondylitis.

NCT ID: NCT04498429 Completed - Clinical trials for Hemiplegia and/or Hemiparesis Following Stroke

Effect of Integrated Cueing on Functional Transfers in Chronic Stroke Survivors

EOIC
Start date: November 6, 2020
Phase: N/A
Study type: Interventional

Physical therapists frequently use manual cueing as a tool to improve movement quality in persons recovering from stroke but evidence to support its effectiveness is lacking. The purpose of this graduate student research study is to determine the immediate and carryover effects of an integrated verbal and manual facilitation approach used by physical therapists during sit to stand training on the midline alignment, muscle activation and quality of movement in chronic stroke survivors with hemiplegia.

NCT ID: NCT04498364 Completed - Tourette Syndrome Clinical Trials

Extinction Learning in Adults With Tourette Syndrome

Start date: September 18, 2020
Phase: N/A
Study type: Interventional

Aversive sensory phenomena such as premonitory urges play a central role in the behavioral treatment model of tics. Extinction learning and extinction recall are learning processes implicated within this model, but are still understudied for individuals with Tourette syndrome (TS). This study examines extinction learning and extinction recall in adults with TS using an experimental task. This study will also explore the relationship between extinction processes (i.e., extinction learning and extinction recall) and treatment outcomes with behavior therapy. Findings from this investigation will be used to update the behavioral treatment model, which serves as the basis for evidence-based behavioral interventions.

NCT ID: NCT04498208 Completed - Surgery Clinical Trials

Immune Modulation by Enhanced vs Standard Prehabilitation Program Before Major Surgery

Start date: October 7, 2020
Phase: N/A
Study type: Interventional

Over 30 million surgeries are performed annually in the US. Up to 30% of surgical patients experience delayed surgical recovery, marked by prolonged post-surgical pain, opioid consumption, and functional impairment, which contributes $8 billion annually to US health care costs. Novel interventions that improve the resolution of pain, minimize opioid exposure, and accelerate functional recovery after surgery are urgently needed. Multi-modal pre-operative optimization programs (or "prehab") integrating exercise, nutrition, and stress reduction have been shown to safely and effectively improve outcomes after surgery. However, no objective biological markers assess prehab effectiveness and are able to tailor prehab programs to individual patients. Surgery is a profound immunological perturbation, during which a complex network of innate and adaptive immune cells is mobilized to organize the recovery process of wound healing, tissue repair, and pain resolution. As such, the in-depth assessment of a patient's immune system before surgery is a promising approach to tailor prehab programs to modifiable biological markers associated with surgical recovery. The primary goal of this clinical trial is to determine the effect of a personalized prehab program on patients immunological status before surgery.

NCT ID: NCT04497792 Completed - Clinical trials for Coronary Artery Disease

Safety and Efficacy of Empagliflozin for Patients With Diabetes Mellitus and Planned Percutaneous Coronary Interventions

SAFARY
Start date: November 2016
Phase: Phase 4
Study type: Interventional

Aim: To study the effectiveness and safety of empagliflozin as a preoperative preparation tool, as well as to improve the long-term prognosis of planned percutaneous coronary interventions in patients with type 2 diabetes

NCT ID: NCT04497714 Completed - Clinical trials for Ultrasound Therapy; Complications

Identifying Ultrasonic Diagnostic Characteristics of Cervical Lymphadenopathy: A Retrospective, Multicenter Study

Start date: January 1, 2017
Phase:
Study type: Observational

The observed indexes of the four cervical lymph node diseases were identified by informatics methods, and the differences in the diagnosis of the four diseases were evaluated, so as to improve the clinical diagnosis rate and provide a research basis for the ultrasonic evaluation of the surgical indications of cervical lymph node diseases in the future.

NCT ID: NCT04497337 Completed - Clinical trials for Superficial Cyst or Mass and Sinus on and Around the Ear

The Superficial Lesions in the Peri-auricular Region

Start date: December 12, 2019
Phase: N/A
Study type: Interventional

Superficial lesions on and around the ear are uncommon with many differential diagnoses and different characteristic histopathologic features. The purpose of this study was to describe a series of peri-auricular superficial lesions and characterize the distinctive types of these lesions.

NCT ID: NCT04497090 Completed - Clinical trials for Pulmonary Disease, Chronic Obstructive

Adaptive Non-invasive Ventilation to Abolish Tidal Flow Limitation

Start date: October 23, 2014
Phase: N/A
Study type: Interventional

This study aimed to evaluate the effects of a novel automatic non-invasive ventilation (NIV) mode that continuously adjusts expiratory positive airway pressure (EPAP) to the lowest value that abolishes tidal expiratory flow limitation. The investigators conducted a prospective, randomized, cross-over study on stable chronic obstructive pulmonary disease (COPD) patients. Patients were studied in the hospital during two non-consecutive nights while using either fixed or adaptive EPAP. The primary outcome was the transcutaneous partial pressure of carbon dioxide. Secondary outcomes were: oxygen saturation, breathing pattern, oscillatory mechanics, patient-ventilation asynchronies, sleep quality and sleep-related respiratory events.

NCT ID: NCT04496908 Completed - Clinical trials for Induction of Labor Affected Fetus / Newborn

Early Versus Delayed Artificial Rupture of Membranes (AROM Trial)

AROM
Start date: September 16, 2020
Phase: Early Phase 1
Study type: Interventional

This randomized controlled trial of consenting women undergoing induction of labor with combined combination Foley catheter and pharmacologic cervical ripening seeks to efficacy of early amniotomy. This project will include 157 women presenting at Christiana Care Health System. Women will be included if they are at least 37 weeks gestation, have a singleton pregnancy, have intact membranes and are undergoing an induction of labor using a Foley catheter combined with either misoprostol or pitocin. Following admission, women will be randomized into either early or delayed amniotomy Women will be randomized with equal probability to the intervention group using block randomization stratified by party. Prior to discharge from the hospital, baseline demographic and clinical data will be obtained via chart review

NCT ID: NCT04496388 Completed - Clinical trials for Exercise, Insulin Resistance, Visceral Adipose Tissue

The Effect of Different Types of Exercise on Insulin Resistance and Visceral Adipose Tissue in Community Residents.

Start date: April 7, 2020
Phase: N/A
Study type: Interventional

Background: Exercise has been proven to effectively reduce incidence of diabetes mellitus and metabolic syndrome. However, there is controversial data from prior studies to inform the type of exercise training recommendations. Aim: The aim of this study will determine the differences of different type of exercise in the effects of reducing insulin resistance and visceral adipose tissue for community residents. Methods: The four-arm randomized controlled trial will conducted in adults aged 40 to 70 years old in Tainan. A total of at least 177 patients will randomly assign to the group of aerobic exercise (AE), aerobic exercise combined with resistance exercise (RE), AE combined with medium intensity interval training, and placebo. The participants in exercise group will received 12 weeks, 3 times per week program, including twice a week intervention guided by the intervenors, and once a week exercise guided by the video at home. All the exercise keeps moderate-intensity by monitoring with 64%-75% of the maximum heart rate. Insulin resistance status will be checked by HOMA index at baseline and at exercise intervention after 12 weeks (HOMA index= insulin μU/mL)× glucose(mmol/L)/22.5). Relevance to clinical practice: The research findings will help the clinical health works to know which type of exercise is the best choice in reducing insulin resistance and visceral adipose tissue in community residents, and can be promoted to the general public to reduce the prevalence of metabolic syndrome as well as prevent the root causes of ill health.