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NCT ID: NCT04628221 Completed - Clinical trials for Adverse Effects in the Use of the OsteoProbe System

Open Label Study Using OsteoProbe System

OP
Start date: July 31, 2020
Phase: N/A
Study type: Interventional

Prospective, Single Center, Open Label Clinical Study. The purpose of the study is to collect safety data associated with the use of the OsteoProbe System. Study Duration is expected to take approximately 3 months from first subject enrolled to the last follow-up visit.

NCT ID: NCT04628169 Completed - Clinical trials for Pathophysiology of Placenta Accreta

Impact of Netrin-1 in the Pathophysiology of Placenta Accreta Spectrum

Start date: December 1, 2021
Phase:
Study type: Observational

The main goal of this study the possible involvement of netrin-1 into the pathophysiology of placenta accrete spectrum. To delineate the role of netrin-1, neogenin - zeb1 signaling pathway in mechanism of morbidly adherent placenta.

NCT ID: NCT04626869 Completed - Clinical trials for Anterior Suprascapular Nerve Block

Anterior Suprascapular Nerve Block is an Effective and Diaphragm Protective Approach for Arthroscopic Shoulder Surgery

Start date: December 1, 2020
Phase: Phase 4
Study type: Interventional

Interscalene block is still the gold standard in shoulder surgery analgesia. The most important side effect is diaphragm paralysis due to the phrenic nerve being affected. It may cause symptomatic dyspnea, especially in patients with limited respiratory capacity. There are studies showing that an effective analgesia, as much as the interscalene block can do, can be provided by blocking the suprascapular nerve in the neck region. The aim of our study is to show that the anterior suprascapular block applied with ultra-low volume (5ml) in shoulder arthroscopy operations is at least as effective as the interscalene block and does not cause diaphragm paralysis.

NCT ID: NCT04626661 Completed - Healthy Clinical Trials

Mitochondrial Oxygen Measurement Variability in Critically Ill Patients (INOX Variability Study)

Start date: June 15, 2020
Phase:
Study type: Observational

To determine the between- and within-subject variability of the mitochondrial oxygenation measurement with the COMET device over time in healthy subjects and in hemodynamically stable subjects admitted to the intensive care unit.

NCT ID: NCT04626622 Completed - Influenza Clinical Trials

Kagocel® for the Prevention of ARVI and Influenza in Young People

Start date: February 15, 2018
Phase:
Study type: Observational [Patient Registry]

This study evaluates the use of Kagocel for the prevention of acute respiratory viral infections (ARVI) and influenza during the epidemic rise in the incidence of diseases in Russia in 2018 (epidemiology: the number of cases during the period of Kagocel administration and follow-up, bacterial exacerbations, the number of repeated episodes (reinfection), demographics of patients, safety, adherence to treatment) in students at risk due to stress, lack of sleep and fatigue.

NCT ID: NCT04626128 Completed - Clinical trials for Neovascular Age-related Macular Degeneration

Safety and Tolerability Study of Suprachoroidal Injection of CLS-AX Following Anti-VEGF Therapy in Neovascular AMD

OASIS
Start date: December 15, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

To evaluate the safety and tolerability of suprachoroidally administered CLS-AX following intravitreal anti-VEGF therapy in subjects with neovascular age-related macular degeneration (AMD)

NCT ID: NCT04625985 Completed - Clinical trials for Severe Acute Respiratory Syndrome Coronavirus 2

Metformin Glycinate, Treatment of Patients With COVID-19 and Severe Acute Respiratory Syndrome Secondary to SARS-CoV-2.

DMMETCOV19-2
Start date: July 14, 2020
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of the metformin glycinate and standard treatment of the hospital in hospitalized patients with Severe Acute Respiratory Syndrome secondary to SARS-CoV2.

NCT ID: NCT04625179 Completed - Clinical trials for Edentulous; Alveolar Process, Atrophy

Melatonin and Hyaluronic Acid in Maxillary Sinus Augmentation

Start date: December 3, 2019
Phase: N/A
Study type: Interventional

melatonin proved an ability to repair bone defects and enhance osseointegration of dental implants. Also, hyaluronic acid has osteopromoting properties. the effect of melatonin and hyaluronic acid on the newly formed bone in maxillary sinus augmentation was evaluated

NCT ID: NCT04625101 Completed - Clinical trials for Epileptic Encephalopathy

Efficacy, Safety, Tolerability, and Pharmacokinetics of NBI-827104 in Pediatric Subjects With Epileptic Encephalopathy With Continuous Spike-and-Wave During Sleep

Start date: April 26, 2021
Phase: Phase 2
Study type: Interventional

This is a phase 2, double-blind study to assess the efficacy, safety, tolerability, and pharmacokinetics of NBI-827104 when administered once daily for 13 weeks in pediatric subjects with Epileptic Encephalopathy with Continuous Spike-and-Wave During Sleep (EECSWS).

NCT ID: NCT04624776 Completed - Cardiac Arrest Clinical Trials

Steroid Treatment After Resuscitated Out-of-Hospital Cardiac Arrest

STEROHCA
Start date: October 10, 2020
Phase: Phase 2
Study type: Interventional

Comatose patients resuscitated from Out-of-Hospital Cardiac Arrest (OHCA) often develop a complicated systemic inflammatory response and have a poor prognosis with neurological damage being the most common cause of death. This study will investigate the anti-inflammatory and neuroprotective effect of early treatment with the glucocorticoid methylprednisolone measured by interleukin-6 and neuron-specific enolase levels in resuscitated comatose OHCA-patients.