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NCT ID: NCT05795127 Active, not recruiting - Surgery Clinical Trials

Risk for Reoperation After First MTP Joint Arthrodesis

Start date: October 1, 2022
Phase:
Study type: Observational

We will screen all first metatarsophalangeal joint arthrodeses performed between 2010 and 2022 in Helsinki University Hospital. Information about demographics and additional diagnoses will be yielded from data pool of medical records. Additionally we review pre- and post-operative x-rays for first MTP joint angles and OR records for operative techniques. Our aim is to find associations between those known variables and risk for reoperation in two years after operation.

NCT ID: NCT05792501 Active, not recruiting - Clinical trials for Ventilator Associated Pneumonia (VAP)

Pulmonary Infections and Barotrauma Associated With MV IN PICU

Start date: April 1, 2022
Phase:
Study type: Observational

This study aims to determine the incidence, risk factors and outcome of ventilation associated common complication in the PICUs at Assiut University Children Hospital in Egypt.

NCT ID: NCT05790538 Active, not recruiting - Clinical trials for Malignant Solid Neoplasm

Predicting the Impact of Treatment Toxicities on Health During Cancer ( PATTERN )

Start date: October 22, 2020
Phase:
Study type: Observational

This study investigates the effects of treatment from chemotherapy for cancer on symptoms, function, and falls during treatment and through the recovery phase of cancer care. The goal is to identify simple tests that can help medical providers predict which and when patients show increased risk for falls and functional decline and informing rehabilitation providers about which mobility deficits to target.

NCT ID: NCT05787769 Active, not recruiting - Clinical trials for Erectile Dysfunction Following Radiation Therapy

A Randomized Trial to Evaluate Efficacy and Safety of Intracavernosal Injection of Platelet-Rich Plasma Versus Phosphodiesterase Type-5 Inhibitors for Treatment of Erectile Dysfunction.

Start date: March 1, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the efficacy and safety of intracavernosal injection of PRP in patients with moderate to severe ED.

NCT ID: NCT05785832 Active, not recruiting - Clinical trials for Type 2 Diabetes Treated With Insulin

A Randomized Trial Evaluating Control-IQ Technology in Adults With Type 2 Diabetes

2IQP
Start date: June 1, 2023
Phase: N/A
Study type: Interventional

A randomized controlled trial (RCT) to assess the safety and efficacy of use of Control-IQ technology in adults with type 2 diabetes using basal-bolus insulin therapy.

NCT ID: NCT05785286 Active, not recruiting - Clinical trials for Benign Prostatic Hyperplasia (BPH)

To Linguistically and Psychometrically Validate the Hong Kong Chinese Version of the BPH 3-item Questionnaire

Start date: February 27, 2023
Phase:
Study type: Observational

This study is to linguistically and psychometrically validate the translated and culturally adapted Hong Kong Chinese version of the BPH 3-item questionnaire.

NCT ID: NCT05783882 Active, not recruiting - Clinical trials for Unresectable or Metastatic Melanoma

Prolgolimab 250 mg Q3W in Patients With Unresectable or Metastatic Melanoma

FLAT
Start date: February 1, 2022
Phase: Phase 3
Study type: Interventional

Multicentre, single-arm, open-label efficacy, pharmacokinetics, and safety study to demonstrate non-inferiority of prolgolimab 250 mg every 3 weeks versus historical data for prolgolimab 1 mg/kg every 2 weeks in patients with unresectable or metastatic melanoma, as well as collecting pharmacokinetics and safety data. The study is conducted under the same conditions as the previously conducted study BCD-100-2/MIRACULUM. This means that this Study No. BCD-100-8/FLAT has identical parameters such as: - selection criteria for subjects in the study, defining the population, - research centers, - procedures for evaluating effectiveness and safety, - permitted prior and concomitant therapy of the underlying disease.

NCT ID: NCT05773105 Active, not recruiting - Clinical trials for Advanced Hepatocellular Carcinoma

A Study of Cadonilimab Combined With Regorafenib in Patients With Advanced HCC

Start date: February 28, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

To evaluate the efficacy and safety of cadonilimab combined with regorafenib in patients with HCC who progressed on systemic therapy.

NCT ID: NCT05772676 Active, not recruiting - Obesity Clinical Trials

The Effect of Aprepitant Reducing Postoperative Nausea and Vomiting

Start date: December 1, 2022
Phase: Phase 4
Study type: Interventional

The purpose of this study is to assess the efficacy of Aprepitant + standard antiemetic regimen in reducing postoperative nausea and vomiting after laparoscopic gastric sleeve versus placebo + standard antiemetic regimen

NCT ID: NCT05766033 Active, not recruiting - Clinical trials for Orthodontic Appliance Complication

Bracket Failure With a Novel Etchant Paste. A Randomized Clinical Trial

failurerate
Start date: June 2, 2022
Phase: N/A
Study type: Interventional

To investigate metallic brackets failure rate bonded post enamel conditioning with a novel CaP etchant paste in comparison with those bonded following conventional enamel etching with PA gel over a period of 6 months.