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NCT ID: NCT05494957 Not yet recruiting - Clinical trials for Nontuberculous Mycobacterial Lung Disease

Clinical Study of New Intensive Treatment Regimen for Severe Nontuberculous Mycobacterial Pulmonary Disease

NTM-PD
Start date: August 5, 2022
Phase: Phase 4
Study type: Interventional

Investigators have selected a number of new drugs, including bedaquiline, to form a regimen to conduct clinical studies for the treatment of severe NTM lung disease.

NCT ID: NCT05493969 Not yet recruiting - Clinical trials for Acquired Immunodeficiency Syndrome

Efficacy and Tolerability of DTG Plus 3TC in HIV Infected Adults With Virologically Suppression and TDF Toxicity

Start date: August 2022
Phase: Phase 4
Study type: Interventional

To investigate the efficacy and tolerability of the regimen of dolutegravir plus lamivudine in HIV infected adults who are virologically suppressed and with evidence of TDF toxicity.

NCT ID: NCT05493774 Not yet recruiting - Virtual Reality Clinical Trials

Preliminary Exploration of Applying Multi-person Simulation Training to Improve Nurse-led Burn and Scald Nursing Care

Start date: April 1, 2023
Phase: N/A
Study type: Interventional

The purpose of this study was to compare the learning performance of trainees before and after learning burns and scald nursing care by applying the burns and scald virtual reality (VR) training module multi-person interactive training in different places and the traditional training model with a high-fidelity patient.

NCT ID: NCT05492266 Not yet recruiting - Clinical trials for Velopharyngeal Insufficiency

Expiratory Muscle Strength Training for Hypernasal Speech in Children

Start date: February 2024
Phase: N/A
Study type: Interventional

When the soft palate does not move enough because of a cleft palate or for unknown reasons, this can lead to a speech difference called velopharyngeal insufficiency. The purpose of this research study is to test if soft palate exercises using a hand help breathing device will help improve the ability of the soft palate to close the area between the throat and nose and help improve speech.

NCT ID: NCT05491694 Not yet recruiting - Breast Cancer Clinical Trials

To Evaluate the Efficacy of Toripalimab Combined With Chemotherapy After HIFU Induction in the Treatment of Early Triple-negative Breast Cancer

HIFU
Start date: September 1, 2022
Phase: Phase 2
Study type: Interventional

To investigate the efficacy and safety of terbinumab combined with chemotherapy (epirubicin + cyclophosphamide → nab-paclitaxel + carboplatin) in neoadjuvant therapy of triple-negative breast cancer after HIFU.

NCT ID: NCT05487846 Not yet recruiting - Clinical trials for Metastatic Prostate Carcinoma

Peer Navigation for the Support of Metastatic Prostate Cancer Patients Undergoing Genetic Evaluation

Start date: November 14, 2024
Phase: N/A
Study type: Interventional

This clinical trial evaluates whether having a trained peer navigator helps African American men with prostate cancer that has spread to other parts of the body (metastatic) understand and navigate the genetic testing process better than not having a peer navigator. Genetic testing for men with prostate cancer is very important for making treatment and management decisions. However, understanding the risks, benefits, and steps of genetic counseling and testing can be very challenging for patients. African American men are especially less likely to participant in genetic testing due to lack of awareness or understanding, cultural beliefs, finances, or mistrust of the healthcare system. A peer navigator, someone who helps a patient through the information and the process, may be helpful to some men. This study evaluates whether having a peer navigator throughout the genetic evaluation process helps patients understand and engage in the process more.

NCT ID: NCT05486091 Not yet recruiting - Clinical trials for Suicidal and Self-injurious Behavior

A Feasibility Open Trial of App-Enhanced Brief CBT for Suicidal Inpatients

Start date: August 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the feasibility of integrating Brief Cognitive-Behavioral Therapy (BCBT) counseling with a software application (app) to prevent future suicidal thoughts and behaviors.

NCT ID: NCT05484583 Not yet recruiting - Lung Cancer Clinical Trials

Durvalumab Combined With Consolidation Radiotherapy After First-line Treatment in Extensive Stage Small Cell Lung Cancer With Oligometastases

Start date: August 1, 2022
Phase: Phase 2
Study type: Interventional

In patients with oligometastatic (1-5 lesions) extensive-stage small cell lung cancer, to explore the efficacy and safety of Durvalumab immunotherapy combined with chemotherapy followed by consolidation radiotherapy, to provide scientific basis for the formulation of the best comprehensive treatment plan in the future.

NCT ID: NCT05484375 Not yet recruiting - Clinical trials for Metastatic Nasopharyngeal Carcinoma

Capecitabine Plus Toripalimab Maintenance Therapy in Metastatic Nasopharyngeal Carcinoma After First-line Treatment

Start date: September 2022
Phase: Phase 2
Study type: Interventional

to evaluate the efficacy and safety of toripalimab and capecitabine maintenance therapy in patients with metastatic nasopharyngeal carcinoma (NPC) after first-line gemcitabine/cisplatin combined with toripalimab.

NCT ID: NCT05484102 Not yet recruiting - Children, Only Clinical Trials

Preventive Effect of Cow's Milk Fermented With Lactobacillus Paracasei CBA L74 on Common Infectious Diseases in Children

FERCT19
Start date: September 15, 2022
Phase: N/A
Study type: Interventional

this is a double-blind randomized placebo controlled clinical trial. 200 healthy children aged 12-48 months, attending day care or preschool for at least 5 days a week, regularly checked by the family pediatrician (FP) involved in the trial, were considered for the study and consecutively contacted during scheduled medical examinations at the FPs office. study plan is 3-month treatment period. The clinical evaluation will be carried out at enrollment, at 30, 60 and 90 days from the beginning of the treatment by the pediatrician. fecal and nasal mucus samples for immunological and microbiological analysis will be collected before the treatment and at 90 days (end of treatment).