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NCT ID: NCT05318443 Completed - Clinical trials for Non-squamous Non-small-cell Lung Cancer

A Study Exploring Efficacy of SIBP04 in Subjects With Non-squamous Non-small Cell Lung Cancer

Start date: April 17, 2020
Phase: Phase 3
Study type: Interventional

This trial is a randomized, double-blind, parallel-controlled, multicenter phase III clinical study. To evaluate the clinical efficacy of SIBP04 in patients with locally advanced, metastatic or recurrent non-squamous non-small cell lung cancer.

NCT ID: NCT05313438 Completed - Clinical trials for Acute Decompensated Heart Failure

The STIM-ADHF Study

Start date: May 10, 2022
Phase: N/A
Study type: Interventional

The STIM-ADHF Study is a multi-center, observational study to assess the performance and safety of the CPNS System in patients with ADHF.

NCT ID: NCT05312814 Completed - Clinical trials for Pregnancy Complications

Clinical Utility of the Addition of a SNP-based NIPT Zygosity Determination in Twin Pregnancy Management.

ZTWINS
Start date: October 1, 2021
Phase:
Study type: Observational

The ZTWINS registry study is an observational, prospective, multi-center study observing women carrying a twin pregnancy who receive snp-based non-invasive prenatal screening and zygosity assessment as part of their medical care.

NCT ID: NCT05310513 Completed - Clinical trials for Intensive Care Units

The Predictors of ICU Admission of oPRES

Start date: April 1, 2022
Phase:
Study type: Observational

The purpose of this study is to explore the predictors of ICU admission of obstetric posterior reversible encephalopathy syndrome.

NCT ID: NCT05309538 Completed - Clinical trials for Benign Paroxysmal Positional Vertigo

Paroxysmal Positional Vertigo & Repositioning Maneuvers

Start date: January 2, 2021
Phase: N/A
Study type: Interventional

: Benign Paroxysmal Positional Vertigo is a condition related to vestibular system accompanied by dizziness, tinnitus and balance problems leading to increased fall risk and potential disability. Various treatment options are available including pharmacotherapy and vestibular rehabilitation with varied results

NCT ID: NCT05309317 Completed - Nurse's Role Clinical Trials

Preventing Catheter-Associated Urinary Tract Infections With a Virtual Simulation Game

CAUTI-VSG
Start date: May 21, 2022
Phase: N/A
Study type: Interventional

Objective: The purpose of this study was to investigate the effectiveness of a virtual simulation game in improving nursing students' knowledge and abilities in preventing catheter-associated urinary tract infection (CAUTI). Method: The study was designed as a parallel-group, randomized controlled trial. A pre-test on knowledge and abilities will be administered to all students participating in the study. Following the pre-test evaluation, a training session on "CAUTI Prevention" will be held. The present training approach (lecture method) in the curriculum will be employed in this session. Following the training, the students in the sample group will be randomly divided into the experimental group (students using virtual simulation game application) and the control group (students learning with the existing education method) based on their general weighted grade averages using the stratified randomized approach. The experimental group will play the virtual simulation game for seven days. Knowledge and competence assessments (post-test) of the control and experimental groups will be conducted seven days following the training. The virtual simulation game application will be evaluated by the students in the experimental group after the post-test evaluations. The students' positive, negative, and constructive feedback on the virtual simulation game will be solicited during the assessment. In addition, these students will score in a 5-point Likert type to evaluate the statements about the virtual simulation game. Hypothesis: H0-1: There is no difference in knowledge about preventing CAUTI between students using the virtual simulation game method and students in the control group. H1-1: There is a difference in knowledge about preventing CAUTI between students using the virtual simulation game method and students in the control group. H0-2: There is no difference in CAUTI prevention skills between students using the virtual simulation game method and students in the control group. H1-2: There is a difference in CAUTI prevention skills between students using the virtual simulation game method and students in the control group.

NCT ID: NCT05307991 Completed - HIV Infections Clinical Trials

Integrating Enhanced HIV PrEP Into a STI Clinic in Lilongwe

Start date: March 9, 2022
Phase:
Study type: Observational

This is a prospective cohort study evaluating acceptability, feasibility, and effectiveness of integrating HIV pre-exposure prophylaxis (PrEP) into a sexually transmitted infection (STI) clinic alongside assisted partner notification and etiologic STI testing in Lilongwe, Malawi.

NCT ID: NCT05306990 Completed - Diabetes Mellitus Clinical Trials

Statins in Patients With Type 2 Diabetes Mellitus and Previous History of Acute Coronary Syndrome

Start date: April 20, 2017
Phase: N/A
Study type: Interventional

The purpose of this study was to compare the efficacy and safety of high dose atorvastatin (40 mg) versus high dose rosuvastatin (20 mg) in Egyptian type II diabetic patients with previous acute coronary syndrome history. This open-labeled prospective, randomized clinical trial compared once daily atorvastatin 40mg (Ator®) versus once daily rosuvastatin 20mg (Crestor®). The primary outcome was the 50% reduction in low-density lipoprotein cholesterol levels at 12 weeks. The secondary outcome was the achievement of low-density lipoprotein cholesterol level < 55 mg/dl.

NCT ID: NCT05306470 Completed - Pain Clinical Trials

Ethyl Chloride Versus 5% Lidocaine for Topical Anesthesia of Oral Mucosa

Start date: March 1, 2022
Phase: N/A
Study type: Interventional

Local anesthesia in the oral cavity is a pain full experience for the patient. All means should be made to reduce the pain and anxiety of the patient for needle stick procedures. My study aims in elevating the pain experienced by the patient during this procedure by using either cold application with ethyl chloride or 5% lidocaine gel.

NCT ID: NCT05305573 Completed - COVID-19 Clinical Trials

Assessing the Immunogenicity and Safety of a HIPRA's Candidate Booster Vaccination in Adults Fully Vaccinated With Adenovirus Vaccine Against COVID-19.

Start date: March 25, 2022
Phase: Phase 2
Study type: Interventional

Phase IIb clinical trial to assess the Immunogenicity and Safety of a HIPRA's Candidate Booster vaccination (PHH-1V) in adults fully vaccinated with the adenovirus vaccine Vaxevria against COVID-19.