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Osteoarthritis clinical trials

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NCT ID: NCT03601130 Recruiting - Clinical trials for Osteoarthritis, Knee

Assessment of HydroxyColl Bone Graft Substitute in High Tibial Osteotomy Wedge Grafting.

HColl_HTO
Start date: April 30, 2018
Phase: N/A
Study type: Interventional

The overall goal of this study is to demonstrate the safety and efficacy of Hydroxycoll bone graft substitute when used in the treatment of patients undergoing surgical treatment for varus mis-alignment in medial unicompartmental osteoarthritis of the knee. HydroxyColl bone graft substitute will be evaluated when utilized in Open Wedge High Tibial Osteotomy with medial plate fixation. Its safety profile will be evaluated as defined by the number of reported adverse events.

NCT ID: NCT03586700 Recruiting - Knee Osteoarthritis Clinical Trials

Based on the Ultrasound Evaluating the Effect of Xiaozhong Fang Particles for Knee Osteoarthritic With Synovial Fluid

Start date: September 15, 2017
Phase: Phase 2
Study type: Interventional

This study is a randomized, single blind, controlled trial. Aim to compare the effectiveness (especially the absorption degree of the synovial effusion measured by B ultrasonic) of the treatment group with the control group. The treatment group was given Xiao zhong fang granules orally and short wave infrared radiation and the control group was given the placebo Xiao zhong fang granules orally and short wave infrared radiation. To evaluate the clinical efficacy of the Chinese medicine in the treatment of the synovial effusion of knee osteoarthritis.

NCT ID: NCT03560063 Recruiting - Osteoarthritis Clinical Trials

The Hip Arthroplasty Positioning Improvement Study

HAPI
Start date: May 1, 2018
Phase: N/A
Study type: Interventional

The primary objective of this study is to determine whether the Corin Optimised Positioning System (Corin, U.K.) reduces the rate of hip dislocation at one-year post-operatively compared with standard templating in patients undergoing total hip replacement. The secondary objectives of this study are to determine whether the Corin Optimised Positioning System (Corin, U.K.) improves functional outcomes, reduces length of hospital stay, and reduces leg length discrepancy compared with standard templating in patients undergoing total hip replacement.

NCT ID: NCT03550547 Recruiting - Knee Osteoarthritis Clinical Trials

Educational Program Associated With a Conventional Spa Therapy of Knee Osteoarthritis Patients

GETT2
Start date: March 11, 2019
Phase: N/A
Study type: Interventional

The main objective of this work is to measure the efficiency of 18 days SPA Therapy in orientation rheumatology associated with an educational intervention in patients with knee osteoarthritis on a priority objective, personalized and determined by the patient, chosen in the list of 5 objectives determined during the educational assessment.

NCT ID: NCT03547947 Recruiting - Avascular Necrosis Clinical Trials

Clinical and Radiological Outcomes of Medacta Shoulder System

Start date: June 13, 2018
Phase:
Study type: Observational

This is a post-marketing surveillance on Medacta Shoulder System

NCT ID: NCT03542617 Recruiting - Osteoarthritis, Hip Clinical Trials

Effect of Preoperative Intravenous Dexamethasone on Postoperative Pain After Primary Total Hip Arthroplasty

Start date: October 5, 2016
Phase: Phase 4
Study type: Interventional

To compare the effects of preoperative intravenous Dexamethasone between 10 mg and 40 mg with placebo on Postoperative Pain After Primary Total Hip Arthroplasty

NCT ID: NCT03540186 Recruiting - Osteoarthritis Clinical Trials

Epigenorm Antivir Combined With Acupuncture for the Treatment of Osteoarthritis Patients Who Are Overweight or Obese

Start date: June 29, 2018
Phase: N/A
Study type: Interventional

The study evaluates analgesic, antiinflammatory and metabolic effects of a supplement Epigenome-Antivir (extracts of glycyrrhiza roots, hippophae rhamnoides leaves, curcumin, green tea, and vitamin C) combined with acupuncture in patients with knee osteoarthritis (OA) and metabolic syndrome.

NCT ID: NCT03513731 Recruiting - Clinical trials for Osteoarthritis of Facet Joint of Lumbar Spine

Safety of Adipose-derived Regenerative Cells Injection for Treatment of Osteoarthritis of the Facet Joint

Start date: December 7, 2018
Phase: N/A
Study type: Interventional

This is a prospective, randomized, active controlled, single site safety and efficacy study in subjects suffering from chronic lumber back pain due to facet joint osteoarthritis comparing a single ADRC injection generated with the Transpose® RT system into the facet joint.

NCT ID: NCT03503825 Recruiting - Healthy Clinical Trials

[Tc-99m]-RPI-087 as an Imaging Marker in Osteoarthritis of the Knee Compared to Healthy Volunteers

Start date: August 16, 2018
Phase: Phase 1
Study type: Interventional

The main purpose of this study is to test the safety and tolerability of T-087. The study will enroll 6 healthy volunteers (HVs) and 6-18 subjects with KOA. All eligible subjects will receive an intravenous injection of the radioactive investigational product (ip) (T-087), followed by SPECT/CT imaging of the knees and blood tests and clinical assessments for safety monitoring. Healthy volunteers will also have their whole body imaged and have extra blood drawn to determine where T-087 goes in the body. These additional procedures will be done on the same day as the ip administration, and repeated the following day. All subjects will have a final follow-up phone call within 2- 3 business days following the ip administration.

NCT ID: NCT03503305 Recruiting - Clinical trials for Osteoarthritis of the Wrist

Healing Osteoarthritic Joints in the Wrist With Adult ADRCs

Start date: November 21, 2018
Phase: N/A
Study type: Interventional

This is a prospective, randomized, double-blinded, active controlled, single site safety and efficacy study in subjects suffering from chronic wrist osteoarthritis comparing a single ADRC injection generated with the Transpose® RT system into the wrist.