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Osteoarthritis, Hip clinical trials

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NCT ID: NCT00951145 Active, not recruiting - Clinical trials for Osteoarthritis of the Hip

Medium and Long Term Outcome of Total Hip Arthroplasty Using Accolade TMZF Femoral Stem

Start date: n/a
Phase: N/A
Study type: Observational

This is a retrospective/prospective study evaluating the clinical and radiographic outcome of total hip arthroplasty (THA) performed using Accolade femoral stem in a consecutive group of patients. All patients eligible for inclusion will be identified. The investigators hypothesize that the outcome of THA performed using Accolade femoral stem is equal or superior to historical survivorship of THA using other types of collarless, proximally coated, tapered stems.

NCT ID: NCT00722982 Active, not recruiting - Coxarthrosis Clinical Trials

Migration Pattern of C-stem AMT Versus Exeter in Total Hip Arthroplasty

Start date: July 2008
Phase: N/A
Study type: Observational

Hypothesis: Migration of C-Stem AMT is equal to the well documented Exeter prosthesis In Norway it is annually performed approximately 600 primary and 100 revisions THA. Osteolysis around the prosthesis is one of the major difficulties while performing revision surgery. C-stem is a triple tapered cemented prosthesis designed to increase the stress and strain of proximal femur and thereby decreasing osteolysis. We are planning til include 70 patients and randomize to C-stem AMT or Exeter prosthesis. Both prosthesis will be combined with previously non documented "Marathon" acetabular prosthesis. The result will be followed clinically and with RSA and DXA. Soft endpoint after 2 years

NCT ID: NCT00709566 Active, not recruiting - Hip Osteoarthritis Clinical Trials

EMPART - Exercise and Manual Physiotherapy Arthritis Research Trial

EMPART
Start date: April 2008
Phase: Phase 3
Study type: Interventional

Hip osteoarthritis is a major cause of disability and reduced quality of life. Physiotherapy, which encompasses a range of interventions such as exercise therapy, manual therapy, education and electrophysical agents, is a core component of management. To date, exercise therapy to date has the greatest evidence of effect . However, this evidence is limited as only a short-term benefit has been identified and improvements in pain and function decline over time. There is some limited evidence for a beneficial effect of manual therapy over exercise. However, clinically these interventions are used in combination, not in isolation. To date, no research has investigated the combined effect of exercise and manual therapy in hip OA. A multi-centre randomised controlled trial that compares the clinical effectiveness of a combination of manual therapy and exercise to exercise therapy only will be conducted.

NCT ID: NCT00551967 Active, not recruiting - Clinical trials for Osteoarthritis of Hip

Evaluation of the Wear of Vitamin E Treated Polyethylene Components in Primary THA Using RSA

Start date: October 2007
Phase: N/A
Study type: Interventional

The specific aim of this proposed study is to conduct a prospective RSA clinical study at Massachusetts General Hospital involving 50 patients receiving primary total hip replacements. All patients will receive the vitamin E treated polyethylene acetabular inserts. Short-term femoral head penetration and long-term steady state wear of the polyethylene will be measured using both RSA and Martell analysis techniques. Stability of the acetabular and femoral components will be measured in all patients using RSA analysis. The stability of the cemented femoral stems will be compared to the stability of the cementless femoral components as well as to historic data in the literature. In addition, all patients will complete a self-administered questionnaire to assess the clinical outcome of the surgery and patient satisfaction.

NCT ID: NCT00545285 Active, not recruiting - Clinical trials for Osteoarthritis of Hip

Long-Term Multi-center Evaluation of E-Poly and Regenerex

Start date: November 2007
Phase: N/A
Study type: Interventional

There are two distinct aims of this study: 1. This prospective study is designed to document the long-term (10-year) radiographic and clinical outcomes of a new type of highly cross-linked polyethylene liner which contains vitamin E as an anti-oxidant, (E-Poly), in a group of primary total hip arthroplasty subjects. The clinical outcome of E-Poly will be compared to a group of subjects receiving Arcom XL polyethylene. 2. This study is also designed to document the long-term (10-year) radiographic and clinical outcomes of a new cementless acetabular component having a titanium porous surface (Regenerex). The clinical outcome of this new FDA cleared device will be compared a group of subjects receiving an acetabular component having a plasma sprayed surface.

NCT ID: NCT00523172 Active, not recruiting - Osteoarthritis, Hip Clinical Trials

Clinical Assessment of Two Manipulative Protocols in Treatment of Hip Osteoarthritis

Start date: October 2007
Phase: Phase 0
Study type: Interventional

Purpose of this study is to examine the effect of chiropractic adjusting (manipulative therapy) and rehabilitation on hip osteoarthritis (hip OA) in older adults.

NCT ID: NCT00522106 Active, not recruiting - Osteoarthritis Clinical Trials

The Effectiveness of Behavioral Graded Activity in Patients With Osteoarthritis of the Hip and/or Knee

GRADIT
Start date: May 2001
Phase: N/A
Study type: Interventional

We performed a randomized controlled trial to study the effectiveness of Behavioral graded activity (BGA) in patients with OA of the hip or knee. It was hypothesised that in the long term BGA results in less pain, less limitations in activities, and better patient global assessment (i.e. the effect of treatment perceived by patients themselves), compared to usual care of physiotherapists (UC). UC was operationalized as physiotherapeutic care according to the Dutch physiotherapy guideline for patients with hip and/or knee OA. It was also investigated whether specific subgroups of patients benefited more from BGA and which factors influenced the success of BGA-treatment. Also, it will be investigated whether differences exist in exercise adherence and whether there is a relationship between exercise adherence and long-term effectiveness.

NCT ID: NCT00481338 Active, not recruiting - Knee Osteoarthritis Clinical Trials

Prevalence,Natural History,Prognosis Factor,QualityofLife,Health Care Consumption and Social Consequences of Symptomatic Knee and Hip Osteoarthritis in France

KHOALA
Start date: April 2007
Phase: N/A
Study type: Interventional

The aim of the project is to assemble and to follow on a 10-year period a nationwide representative sample of lower limb OA patients. General objectives: To document the natural history and to identify predictive factors of the evolution and consequences of hip and knee OA in terms of pain, functional disability, structural damage, quality of life, autonomy, medical and health care use and cost of disease.

NCT ID: NCT00318396 Active, not recruiting - Coxarthrosis Clinical Trials

Compaction Femur Preparation for Cementless Total Hip Arthroplasty (THA) Unilateral

Start date: June 2004
Phase: N/A
Study type: Interventional

This is a prospective, randomized study comparing two different bone preparation techniques for insertion of a hydroxylapatite (HA) coated titanium cementless femoral stem. Patients who receive a unilateral total hip replacement are randomized to either conventional broaching or compaction. Hypothesis: Compaction results in significantly less stem migration [evaluated by radiostereometric analysis (RSA)], less peri-prosthetic bone mineral density (BMD) loss [evaluated by dual energy x-ray absorptiometry (DEXA)], and a higher Harris hip score after two years.

NCT ID: NCT00294424 Active, not recruiting - Clinical trials for Osteoarthritis, Knee

Study on Costs and Effects of Waiting Time in Total Hip and Knee Replacements

Start date: September 2002
Phase: N/A
Study type: Interventional

The aim of this study is to compare the cost-effectiveness of major joint replacement in patients with short and non-fixed (control group) waiting time (WT). After being placed on the waiting list, patients will be randomized into two groups through regular contact with the practice staff: (1) Patients with non-fixed waiting time (patient undergoes hospital's normal procedure from the date (s)he is added to the waiting list to the date of operation), and (2) patients with short waiting time (operated in maximum three months). The main question is: is it possible to improve the cost-effectiveness of major joint replacement by shortening waiting time?