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NCT number NCT03239717
Study type Interventional
Source University of Wisconsin, Madison
Contact Dudley W Lamming, PhD
Phone 608-256-1901
Email dlamming@medicine.wisc.edu
Status Recruiting
Phase N/A
Start date July 28, 2017
Completion date October 5, 2018

Clinical Trial Summary

Branched-chain amino acids (BCAAs) are essential nutrients that the body obtains from proteins found in food, especially meat, diary products, and legumes. Data from rodent studies suggest that reduction of dietary BCAAs will promote fat mass loss and improved control of blood glucose. The purpose of this study is to test if reduction of dietary BCAAs without reducing calorie intake will lead to similar metabolic benefits in humans. Here the investigators test the feasibility of reducing dietary BCAAs using BCAA-free meal replacement beverages for two months.


Clinical Trial Description

This study, which will be completed over three months, involves replacing two meals a day with meal replacement beverages for two months, with a one month follow-up visit. These beverages will be made up by subjects using either a complete protein powder or BCAD2, a BCAA-free medical food. Subjects will complete food diaries at baseline and at one month intervals during the study, and compliance will be assessed via food diaries, weekly telephone contact, and measuring returned food powder.


Study Design


Related Conditions & MeSH terms


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