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Mutation of the LEPR Gene at Reunion Island: Involvement in Pediatric Obesity — GREOL  

Obesity, Childhood Clinical Trial

Official title:
Mutation of the LEPR Gene at Reunion Island: Involvement in Pediatric Obesity GRÉOL (Génétique Réunion Obésité LEPR)

Clinical Trial Summary

The objective of this study is to estimate the proportion of the recurrent deletion Δ6-8 of the LEPR gene in the homozygous and heterozygous state in pediatric cases with severe and early ( before the age of 6) obesity (BMI ≥ IOTF-30) on Reunion Island.

Clinical Trial Description

The study of the deletion Δ6-8 of the LEPR gene starts with a saliva sample using a swab in children aged between 3 to 18 years old. The DNA from this sample will then be analyzed by the PCR technique. If the deletion of the LEPR gene is confirmed in the patient, his adult family members will also be screened using the same procedure. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04329260
Study type Observational
Source Centre Hospitalier Universitaire de la Réunion
Contact Emilie TECHER
Phone +262 262 90 62 89
Email emilie.techer@chu-reunion.fr
Status Not yet recruiting
Phase
Start date March 2021
Completion date December 2022
View Details
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