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Neuralgia clinical trials

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NCT ID: NCT03189823 Completed - Pain, Intractable Clinical Trials

Long-term Effect of Motor Cortex Stimulation in Patients Suffering From Chronic Neuropathic Pain

MCSNL
Start date: January 1, 2003
Phase: N/A
Study type: Observational

In order to create insights in the effects of Motor cortex stimulation (MCS) on intractable pain, an open observational study was started in 2003. The aim of this research is to: 1. to determine the clinical effectivity of MCS on pain intensity after 1 month, 1 year and 3 years of stimulation 2. to determine the clinical effectivity of MCS on QoL and daity medication intake after 3 years of MCS

NCT ID: NCT03160937 Completed - Movement Disorders Clinical Trials

Neurodynamic Mobilization and Foam Rolling

Start date: January 10, 2017
Phase: N/A
Study type: Interventional

The purpose of this study was to assess the acute effects of a single NM treatment session on DOMS and to compare them with those of one foam roller (FR) session. Following the damaging plyometric exercise bout, the participants were randomly assigned in a counter-balanced fashion to either a FR or NM treatment group; treatments were administered 48-h post-exercise. The dependent variables were recorded before the exercise, 48-h post-exercise before treatment, and immediately post-treatment.

NCT ID: NCT03131466 Completed - Clinical trials for Idiopathic Trigeminal Neuralgia

High-voltage Pulsed Radiofrequency on Gasserian Ganglion to Treat Patients With Primary Trigeminal Neuralgia

Start date: April 28, 2017
Phase: N/A
Study type: Interventional

The study is designed to compare the effectiveness and safety of high-voltage Pulsed radiofrequency and nerve block for the treatment of primary Trigeminal Neuralgia patients with ineffective conservative treatment and explore better non-surgical treatment methods for Trigeminal Neuralgia patients.

NCT ID: NCT03124511 Completed - Clinical trials for Chronic Chemotherapy-induced Pain

Neuropathic Pain After Breast Surgery

Start date: August 15, 2017
Phase:
Study type: Observational

To understand pain pathophysiology in terms of risk factors and protective mechanisms ranging from molecular pathways to societal impacts.

NCT ID: NCT03121976 Completed - Pain Clinical Trials

A Comparison of US and Evoked Motor Response-guided Placement of Continuous Femoral Nerve Block Following TKA

Start date: January 2, 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to determine which technique for catheter placement in continuous femoral nerve block (FNB) is most successful - guidance with (1) ultrasound or (2) nerve stimulation and ultrasound. Sensory and motor assessment scores will be obtained post-FNB. Patient controlled analgesia and opiate consumption is also recorded along with pain scores for the first 48 hour post-FNB.

NCT ID: NCT03111277 Completed - Clinical trials for Spinal Cord Injuries

MR Guided Focused Ultrasound for Treatment of Neuropathic Pain

Start date: September 15, 2017
Phase: N/A
Study type: Interventional

Neuropathic pain is often a result of direct diseases of peripheral or central nervous system with an estimated prevalence of 8% of adults and this pain is associated with significant consequences because of longer symptom duration and severity than many of the other pain syndromes. Functional brain imaging has revealed that many regions of the brain are engaged by painful events, but specific areas such as the thalamus have been markedly implicated. The purpose of this study is to determine the feasibility and safety of MRI-guided focused ultrasound treatment using the ExAblate Transcranial System in patients suffering from Neuropathic pain. This treatment modality offers non-invasive precise treatment potential for these patients.

NCT ID: NCT03109860 Completed - Neuropathic Pain Clinical Trials

Can the Perception of a Treatment Influence Pain Processing - an Examination of Psychological and Neurobiological Mechanisms

Start date: April 17, 2015
Phase: N/A
Study type: Observational

The study investigates the effect of an open (in full view of the patient) vs hidden treatment (without the patient's knowledge).

NCT ID: NCT03105765 Completed - Chronic Pain Clinical Trials

Acute and Chronic Pain, Especially Neuropathic Pain, After Thoracotomy and Continuous Application of Ketamine.

Start date: January 2011
Phase: N/A
Study type: Interventional

Chronic Pain, especially neuropathic pain, are adverse events after posterolateral thoracotomy for lung resection. The continuous application of ketamine may have a prophylactic effect and helps to prevent chronic pain. The investigators record the incidence and severity of acute pain and neuropathic pain during a seven day period after thoracotomy as well as the incidence of chronic pain and neuropathic pain after one and three month period. Parallel Group design, comparing one Group with a continuous application (24 hours) of ketamine against a Placebo Group.

NCT ID: NCT03099005 Completed - Cannabis Clinical Trials

Effect of Cannabis and Endocannabinoids on HIV Neuropathic Pain

Start date: July 1, 2018
Phase: Phase 2
Study type: Interventional

Acute cannabis administration is reported to alleviate HIV neuropathic pain (HIV-NP), but there is limited knowledge about the effects of cannabis constituents (delta-9 tetrahydrocannabinol/THC and cannabidiol/CBD), the consequences of long-term cannabis use, and the impact of cannabis on endocannabinoid (EC) function in people living with HIV- NP. Our objective is to address these three fundamental gaps in our knowledge by: 1) examining the acute effects of various CBD/THC products on HIV-NP, 2) utilizing a mHealth text messaging protocol, Individual Monitoring of Pain and Cannabis Taken (IMPACT) to monitor daily real-world cannabis use and changes in pain; and 3) studying the relationship between cannabinoids, EC biomarkers, and chronic neuropathic pain

NCT ID: NCT03066570 Completed - Clinical trials for Painful Diabetic Neuropathy

Graded Exposure in Patients With Painful Diabetic Neuropathy

PDN&GEXP
Start date: June 1, 2017
Phase: N/A
Study type: Interventional

Objective: To investigate the effects of a cognitive behavioural intervention targeting specific fears in patients with painful diabetic neuropathy, on physical activity and quality of life.