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Neoplasms clinical trials

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NCT ID: NCT02211196 Completed - Malignant Neoplasm Clinical Trials

Evidence-Based Tobacco Cessation Strategies in Patients With Cancer

Start date: February 2013
Phase: N/A
Study type: Interventional

This pilot clinical trial studies evidence-based tobacco cessation strategies in patients with cancer. Stop-smoking plans suggested by doctors may help patients with cancer quit smoking.

NCT ID: NCT02210078 Active, not recruiting - Clinical trials for Malignant Solid Neoplasm

Donor Cytomegalovirus-Specific Cytotoxic T-Lymphocytes in Treating Patients With a Persistent Cytomegalovirus Infection

Start date: February 19, 2015
Phase: Phase 2
Study type: Interventional

This phase II trial studies how well donor cytomegalovirus-specific cytotoxic T-lymphocytes work in treating patients with a cytomegalovirus infection that has come back or has not gotten better despite standard therapy. White blood cells from donors who have been exposed to cytomegalovirus may be effective in treating patients with a cytomegalovirus infection.

NCT ID: NCT02208804 Recruiting - Clinical trials for Colorectal Neoplasms

Surefire Infusion System vs. Standard Microcatheter Use During Holmium-166 Radioembolization

SIM
Start date: November 2014
Phase: Phase 2/Phase 3
Study type: Interventional

The objective of the SIM trial is to investigate whether using the Surefire Infusion System during holmium-166 radioembolization increases the posttreatment tumor to non-tumor activity concentration ratio, compared with using a standard end-hole microcatheter.

NCT ID: NCT02205047 Active, not recruiting - Clinical trials for Malignant Neoplasm of Stomach

Neoadjuvant Study Using Trastuzumab or Trastuzumab With Pertuzumab in Gastric or Gastroesophageal Junction Adenocarcinoma

INNOVATION
Start date: July 15, 2015
Phase: Phase 2
Study type: Interventional

The purpose of this study is to find out whether either trastuzumab or the combination of trastuzumab and pertuzumab with standard chemotherapy shows more activity against gastro-oesophageal adenocarcinoma than standard chemotherapy given before and after surgery and it can be safely administered.

NCT ID: NCT02204761 Completed - Recurrent Disease Clinical Trials

Proton Beam Re-Irradiation in Thoracic Cancers

Start date: September 9, 2014
Phase: N/A
Study type: Interventional

This pilot clinical trial studies proton beam radiation therapy in treating patients with thoracic cancer that has come back and have received prior radiation therapy. Proton beam radiation therapy uses high energy protons to kill tumor cells and may cause less damage to normal tissue.

NCT ID: NCT02204098 Active, not recruiting - Breast Cancer Clinical Trials

Safety and Immune Response to a Mammaglobin-A DNA Vaccine In Breast Cancer Patients Undergoing Neoadjuvant Endocrine Therapy

Start date: January 7, 2015
Phase: Phase 1
Study type: Interventional

The purpose of this research study is to find out about the safety of injecting the gene (DNA) for mammaglobin-A into people with breast cancer. The DNA used in this study was purified from bacteria and contains the gene for mammaglobin-A. Mammaglobin-A is a protein that is highly expressed by breast cancer cells. Injection of mammaglobin-A DNA may be a way to generate an immune response to breast cancer cells. There is evidence that an immune response may be a way to fight cancer. In addition to evaluating the safety of the mammaglobin-A injection, this study is also looking at the immune response that the participant's body has after each injection.

NCT ID: NCT02203903 Recruiting - Clinical trials for Relapsed/Refractory Hematopoietic Malignancies, Acute Myeloid Leukemia and MDS

Multi-institutional Prospective Research of Expanded Multi-antigen Specifically Oriented Lymphocytes for the Treatment of VEry High Risk Hematopoietic Malignancies

RESOLVE
Start date: January 1, 2015
Phase: Phase 1
Study type: Interventional

This Phase I dose-escalation trial is designed to evaluate the safety of administering rapidly -generated tumor multi-antigen associated -specific cytotoxic T lymphocytes, to HSCT recipients (Arm A) or future HSCT recipients (Arm B) for the treatment of high-risk or relapsed or refractory hematopoietic malignancies. In addition to safety, this study will also evaluate if event-free survival (EFS) is improved with TAA-T administration at six months after HSCT for patients with high risk AML and MDS (Arm C).

NCT ID: NCT02203253 Completed - Neoplasms Clinical Trials

Efficacy of Thalidomide in Preventing Chemotherapy-induced Delayed Nausea and Vomiting

Start date: July 2014
Phase: Phase 3
Study type: Interventional

This study was aimed to evaluate efficacy and tolerability of thalidomide in improving prevention of chemotherapy-induced delayed nausea and vomiting in chemotherapy-naive patients after highly emetogenic chemotherapy.

NCT ID: NCT02202928 Active, not recruiting - Colorectal Cancer Clinical Trials

Adoptive Cell Therapy Plus Chemotherapy and Radiation After Surgery in Treating Patients With Colorectal Cancer

Start date: July 2014
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy of autologous tumor lysate-pulsed dendritic and cytokine-induced killer cells (DC-CIK) for colorectal cancer (CRC).

NCT ID: NCT02199327 Completed - Clinical trials for Corneal Intraepithelial Neoplasia

Topical Interferon Alfa 2b and Mitomycin C in Conjunctival-Corneal Intraepithelial Neoplasia

Start date: May 2014
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the therapeutic efficacy of interferon alfa 2b and topical mitomycin C in patients with diagnosis of conjunctival-corneal intraepithelial neoplasia.