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Neoplasms clinical trials

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NCT ID: NCT06341998 Completed - Germ Cell Tumor Clinical Trials

Clinical Study of Chemotherapy in the Treatment of Recurrent/Refractory Yolk Sac Tumor in Children

SCRRYST
Start date: June 1, 2020
Phase: Phase 2/Phase 3
Study type: Interventional

Remarkable progress has been made in treating germ-cell tumor (GCT) through the use of platinum-based regimens. However, part of yolk sac tumor (YST) with cisplatin resistance or recurrence is nevertheless prone to relapse after second-line treatment. This leaves a gap in effective treatment, which needs to be filled by novel therapeutic approaches. This paper is the first one to report the treatment combining sirolimus with nab-paclitaxel, ifosfamide, and carboplatin (S-TIC) for children with repeated relapsed or refractory yolk sac tumor (rrrYST).

NCT ID: NCT06323135 Completed - Advanced Cancer Clinical Trials

Nutrition Assessment in Advanced Cancer Patients

Start date: September 17, 2019
Phase:
Study type: Observational

The goal of this retrospective observational study is to evaluate the prognostic value of nutrition assessment tool in advanced cancers. We aim to evaluate the clinical utility of nutrition assessment tool in predicting the clinical outcomes of cancer patients, which would help the clinicians to make tailored decision for this population.

NCT ID: NCT06311032 Completed - Clinical trials for Surgery Risk Assessment

Clinician Decision Making Regarding Surveillance for Low-risk Intraductal Papillary Mucinous Neoplasms of The Pancreas

Start date: March 29, 2023
Phase:
Study type: Observational

The main objective of this study is to determine how physicians make decisions regarding surveillance of Intraductal Papillary Mucinous Neoplasm's (IPMN) of the pancreas.

NCT ID: NCT06266923 Completed - Clinical trials for Advanced Solid Tumor

A Clinical Study of SPH6516 Tablets in the Treatment of Advanced Solid Tumors.

Start date: January 20, 2022
Phase: Early Phase 1
Study type: Interventional

To evaluate the safety, tolerability, pharmacokinetics and preliminary efficacy of SPH6516 tablets in the treatment of advanced solid tumors.

NCT ID: NCT06231277 Completed - Solid Tumours Clinical Trials

Phase I Clinical Trial of BH002 in Patients With Advanced Solid Tumors

BH002-?-101
Start date: April 26, 2022
Phase: Phase 1
Study type: Interventional

The goal of this clinical trial is to about in Patients With Advanced Solid Tumors. The main question[s] it aims to answer are: - question 1:Evaluating the tolerability of BH002 injection in Chinese patients with advanced solid tumors - question 2:Obtain the pharmacokinetic (PK) characteristics of BH002 injection in Chinese patients with advanced solid tumors

NCT ID: NCT06206642 Completed - Malignant Neoplasm Clinical Trials

Comparing 18F-FAPI-04 and 18F-FDG PET/CT in Cancer Detection

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

Evaluating fluoro-18-fibroblast activation protein inhibitor-04 positron emission computed tomography's diagnostic efficacy for primary malignancies versus 18F-2-fluoro-2-deoxy-D-glucose fluorodeoxyglucose.

NCT ID: NCT06181058 Completed - Oncology Clinical Trials

Escape Room Game in Oncology Nursing

Start date: December 25, 2023
Phase: N/A
Study type: Interventional

This research will be conducted to evaluate the effect of the escape room game activity applied to nursing students taking oncology nursing courses on their academic self-efficacy and critical thinking motivation.

NCT ID: NCT06118125 Completed - Advanced Cancer Clinical Trials

Delay to Diagnosis in Digestive Cancerology by the General Practitioner Related to Covid-19 Pandemic Confinement

Start date: June 1, 2019
Phase:
Study type: Observational

Objective: the pre-hospital management of cancers is little known in General Medicine. The first lockdown related to the COVID-19 pandemic led to the closure of health facilities. Investigators were interested in the diagnosis and care pathway of digestive cancers in post-confinement in General Medicine in Nouvelle-Aquitaine.

NCT ID: NCT06093945 Completed - Malignant Tumor Clinical Trials

Effect of Omeprazole on Pharmacokinetics of SHR2554 in Healthy Subjects

Start date: November 6, 2023
Phase: Phase 1
Study type: Interventional

The study aimed to assess the effects of omeprazole on single-dose SHR2554 in healthy subjects, exploring the pharmacokinetic changes of SHR2554 and ensuring the safety when SHR2554 is co-administered with omeprazole.

NCT ID: NCT06090630 Completed - Breast Carcinoma Clinical Trials

MR Correlated Spectroscopic Imaging for Diagnosing Breast Cancer

Start date: July 31, 2017
Phase: N/A
Study type: Interventional

This trial studies how well an imaging technique called magnetic resonance (MR) spectroscopic imaging works in identifying breast cancer in women with benign or suspicious areas in the breast. Magnetic resonance imaging (MRI) is a diagnostic tool used to investigate the location of tumors in different organs. Since radiological pictures do not have sufficient information for tumor grades, invasive procedure such as biopsy is performed on patients with breast cancers for diagnosis. Breast tissue contains water, fat, and chemicals known as metabolites. MR spectroscopic imaging may help to characterize the various breast metabolite steady state levels and identify the differences between necrosis and tumor recurrence, which is difficult using radiological procedures such as MRI.