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Myocardial Ischemia clinical trials

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NCT ID: NCT02959814 Completed - Clinical trials for Coronary Artery Disease

Diagnostic Accuracy of On-line Quantitative Flow Ratio (QFR). FAVOR II Europe-Japan

FAVOR II EJ
Start date: February 22, 2017
Phase:
Study type: Observational

Quantitative Flow Ratio (QFR) is a novel method for evaluating the functional significance of coronary stenosis. QFR is assessed by calculation of the pressure in the vessel based on two angiographic projections. The purpose of the FAVOR II study is to evaluate the diagnostic accuracy of on-line QFR compared to 2D Quantitative Coronary Angiography (QCA) with FFR as gold standard.

NCT ID: NCT02959788 Completed - Clinical trials for Acute Coronary Syndrome

Heart Rate Variability as a Predictor of Ischemic Heart Disease

Start date: April 2016
Phase: N/A
Study type: Observational

Identification of patients who are at highest risk for heart attack is an important task for emergency medicine physicians. Currently, physicians use a variety of different scoring systems to stratify their risk for having a heart attack. Heart rate variability (HRV) is a measure derived from noninvasive cardiac monitoring. This data is collected from a simple, non-invasive chest strap during a 10-minute recording session. The purpose of this proposal is to collect heart rate variability data on patients admitted to the emergency department with chest pain. The intent is to measure the association between heart rate variability and the various risk stratification scoring systems for chest pain.

NCT ID: NCT02947542 Completed - Clinical trials for Stable Coronary Heart Disease

Use of Different Diagnostic Coronary Catheters Over the Radial Access - the UDDC - Radial Trial

UDDC
Start date: April 2016
Phase: N/A
Study type: Interventional

There is no evidence from prospective randomized clinical trials regarding the performance of conventional (two-catheter-concept; TCC) versus one-catheter-concepts (OCC) for invasive coronary angiography over the radial access. The aim of the present trial is to evaluate the efficacy and safety of different one-catheter concepts by use of the BLK and Tiger catheter compared to a TCC using standard Judkins catheters in diagnostic coronary angiography via transradial access. Patients with stable angina pectoris will be randomly assigned to coronary angiography performed with the BLK or Tiger (OCC) or Judkins catheters (TCC). The primary endpoint is coronary angiography duration.

NCT ID: NCT02942628 Completed - Clinical trials for Ischemic Heart Disease

Vegetarian Diet in Patients With Ischemic Heart Disease

VERDI
Start date: October 1, 2017
Phase: N/A
Study type: Interventional

Open label, 4 week randomized, cross-over study to compare the effect of a vegetarian diet to a conventional (meat containing) diet based on the Swedish average meat consumption on a range of parameters with prognostic importance for cardiovascular disease.The study will be conducted in patients diagnosed with ischemic heart disease. We hypothesize that patients will benefit from a vegetarian diet as assessed by multiple risk markers for this type of disease with a primary focus on changes in oxidized LDL cholesterol.

NCT ID: NCT02941380 Completed - Clinical trials for Ischemic Heart Disease

Exploration of Cerebral Pathophysiology During and After CABG Using CPB

Start date: July 2011
Phase: N/A
Study type: Observational

Purpose: The purpose of this study is to examine cerebral oxidative and inflammatory stress and cerebral hemodynamics during and after coronary artery bypass grafting and correlate with postoperative cognitive function.

NCT ID: NCT02930330 Completed - Clinical trials for Coronary Artery Disease

Interval Training in Cardiac Rehabilitation

Start date: October 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether high intensity interval training (INT) is more effective in suppressing platelet reactivity than continuous, moderate intensity training (CONT) in patients undergoing cardiac rehabilitation after percutaneous coronary intervention.

NCT ID: NCT02926807 Completed - Atopic Dermatitis Clinical Trials

Trial on Vascular Inflammation in Atopic Dermatitis

Start date: January 2017
Phase:
Study type: Observational

A total of 30 subjects with moderate to severe atopic dermatitis. Thirty subjects without AD matched for sex, age and coronary artery disease risk factor with the AD subjects will also be included. All subjects will undergo the following imaging procedures: a 18FDG-PET to quantify vascular inflammation in the ascending aorta and carotids and a MDCT to calculate the Agatston score. Skin and blood biomarkers will also be assessed.

NCT ID: NCT02926755 Completed - Clinical trials for Coronary Artery Disease

Multi-modality Imaging in Acute Myocardial Infarction

MIAMI
Start date: January 20, 2016
Phase: N/A
Study type: Interventional

The goal of this study is to use three (3) different imaging techniques:Fractional Flow Reserve (FFR) allows precise measurement of blood flow in the arteries to the heart, and is more reliable than pictures alone to determine the significance of blockages in the heart; Near Infra-Red Spectroscopy-Intravascular Ultrasound (NIRS IVUS) provides information about the amount of lipid and cholesterol in the plaque, and plaque volume; and Optical Coherence Tomography (OCT) allows physicians to assess tears in the surface of plaque and plaque thickness; to evaluate high risk non-infarct-related coronary lesion in patients who have suffered a recent heart attack, underwent successful opening of the artery with a stent, and have blockages greater than or equal to 50% in one or more of the other arteries to the heart; and to correlate this findings with cardiovascular outcomes at 1 year.

NCT ID: NCT02926027 Completed - Clinical trials for Hypertriglyceridemia

Effect of Vascepa on Improving Coronary Atherosclerosis in People With High Triglycerides Taking Statin Therapy

EVAPORATE
Start date: March 28, 2017
Phase: Phase 4
Study type: Interventional

Effect of Vascepa on Progression of Coronary Atherosclerosis in Persons with Elevated Triglycerides (200-499) on Statin Therapy. The study is to determine progression rates of low attenuation plaque under influence of Vascepa as compared to placebo.

NCT ID: NCT02920125 Completed - Clinical trials for Coronary Artery Disease

Study the Result of Ayurvedic SUVED & Reimmugen (Colostrum) Treatment on Vascular Disease, CAD, CVA, DVT.

SHARP
Start date: January 2016
Phase: Phase 3
Study type: Interventional

To evaluate the benefits of Ayurvedic SUVED & REIMMUGEN Colostrum for reduction/reversal of symptoms and study clinical progress in Vascular disease; CAD, CAV, Stroke, DVT patients.