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Half-Dose Intracoronary Abciximab Bolus Improves the Mortality Outcome Compared to Standard Intravenous Regimen

Myocardial Infarction Clinical Trial

Clinical Trial Summary

The aim of our study was to demonstrate that, during a percutaneous coronary intervention, even smaller amounts of abciximab than standard dose, injected locally, could achieve a rapid thrombus resolution and clinical improvement without concomitant differences in hemorrhagic complications

Clinical Trial Description

Patients both with acute myocardial infarction and unstable angina are prone to extensive intracoronary thrombosis, leading to acute deterioration during percutaneous coronary intervention or thrombosis of the device despite therapy. Intracoronary use of abciximab has reported favourable results. We randomly assigned 84 patients to intracoronary half abciximab bolus (group A) and to standard regimen (group B). ;

Study Design

N/A

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00320229
Study type Interventional
Source Azienda Sanitaria Ospedaliera
Contact
Status Terminated
Phase Phase 4
Start date December 2004
Completion date July 2005
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