Morbid Obesity Clinical Trial
Official title:
The Effect of Bi-PAP at Individualized Pressures on the Postoperative Pulmonary Recovery of Morbidly Obese Patients (MOP) Undergoing Open Bariatric Surgery (OBS) and Possible Placebo Device-related Effects (Sham-Bi-PAP)
The effect of biphasic positive airway pressure (Bi-PAP) at individualized pressures on the postoperative pulmonary recovery of morbidly obese patients (MOP) undergoing open bariatric surgery (OBS) and possible placebo device-related effects (sham-Bi-PAP) were investigated.
In the present study the effect of Bi-PAP on the postoperative respiratory function and related complications of MOP undergoing OBS through a randomized sham-controlled design was investigated. Bi-PAP was applied at individualized pressures in order to optimize respiratory support and sham Bi-PAP was also used in order to neutralize possible placebo device related effect and researcher related bias. The investigators hypothesized that the use of Bi-PAP at individualized pressures in MOP undergoing OBS, ameliorates postoperative respiratory function as well as diminishes related pulmonary complications, postoperative pain and duration of hospitalization. Primary endpoints were the difference in pre- and postoperative measurements of certain pulmonary function parameters (forced expiratory volume at one second (FEV1), forced vital capacity (FVC), peak expiratory flow rate (PEFR) and oxygen saturation by pulse oximetry (SpO2) and the incidence of certain pulmonary complications postoperatively (hypoxemia, atelectasis, lower respiratory tract infections). Secondary endpoints were postoperative pain and days of hospitalization. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT03657927 -
A Comparison of McGrath MAC Versus C-MAC Videolaryngoscopes in Morbidly Obese Patients
|
N/A | |
| Recruiting |
NCT04934826 -
Comparison of the Absorption of Hydrolyzed or Intact Proteins in Morbid Obese Patients After the Roux Y Gastric Bypass
|
N/A | |
| Completed |
NCT03181347 -
The Microbiology of Bariatric Surgery
|
N/A | |
| Completed |
NCT03886870 -
Obesity, Lifestyle and Work Intervention
|
N/A | |
| Active, not recruiting |
NCT04433338 -
The PREBA Study: Effect of Preoperative Weight Loss With a 14-day Low-calorie Diet on Surgical Procedure and Outcomes in Patients Undergoing RYGB Surgery
|
N/A | |
| Completed |
NCT03553849 -
Utilization of Very Low Calorie Diet in Obese General Surgery Patients
|
N/A | |
| Completed |
NCT05854875 -
Diabetes Remission After RYGBP and RYGBP With Fundus Resection
|
N/A | |
| Not yet recruiting |
NCT03203161 -
Registry on Obesity Surgery in Adolescents
|
||
| Not yet recruiting |
NCT03601273 -
Bariatric Embolization Trial for the Obese Nonsurgical
|
Phase 1 | |
| Recruiting |
NCT02129296 -
Intragastric Balloon, Air Versus Fluid Filled: Randomized Prospective Study
|
Phase 1/Phase 2 | |
| Active, not recruiting |
NCT01564732 -
Multicenter Prospective Randomized Controlled Trial of Plicated Laparoscopic Adjustable Gastric Banding
|
N/A | |
| Completed |
NCT02033265 -
Ultrasound-Guided Axillary Brachial Plexus Block: Influence of Obesity
|
||
| Completed |
NCT01963637 -
Gastric Volumetry by Gastric Tomodensitometry With Gas
|
N/A | |
| Not yet recruiting |
NCT01652105 -
Randomized Trial of Preoperative Diets Before Bariatric Surgery
|
N/A | |
| Terminated |
NCT01759550 -
Prospective Case-Series of Ligasure Advance Pistol Grip and LigaSure Blunt Tip
|
||
| Completed |
NCT01149512 -
Outcomes of the Adjustable Gastric Band in a Publicly Funded Obesity Program
|
N/A | |
| Completed |
NCT01955993 -
Fentanyl Metabolism in Obese Adolescents
|
N/A | |
| Recruiting |
NCT01685177 -
Single Anastomosis Duodeno-Ileal Bypass vs Standard Duodenal Switch as a Second Step After Sleeve Gastrectomy in the Super-Morbid Obese Patient
|
N/A | |
| Completed |
NCT02414893 -
Hunger/Satiety's Physiopathologic Study in Morbidly Obese Patients
|
N/A | |
| Completed |
NCT02929212 -
Effect of Number of Meals on Metabolism After Weight Loss Surgery
|
N/A |