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Ischemic Stroke clinical trials

View clinical trials related to Ischemic Stroke.

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NCT ID: NCT05169450 Completed - Stroke Clinical Trials

Efficacy of Diterpene Ginkgolides Meglumine Injection in Elderly Patients With Ischemic Stroke

Start date: July 1, 2013
Phase: N/A
Study type: Interventional

A randomized positived-controlled study of Diterpene Ginkgolides Meglumine Injection (DGMI) vs Ginaton in patients with ischemic stroke (IS) was conducted between7/2013 and 4/2014. The study was designed to test efficacy of DGMI for IS. Post hoc analysis of this trial was conducted to evaluate the efficacy of DGMI in elderly (aged≄65 years) IS patients.

NCT ID: NCT05166733 Not yet recruiting - Neurology Clinical Trials

A Retrospective Study of Reco Thrombectomy Stent for Intravascular Treatment of Acute Ischemic Stroke

Start date: December 2021
Phase:
Study type: Observational

To explore the differences in the green channel process of stroke in various regions of the same province, to target and shorten the time delay of emergency process, and to explore the key technologies of endovascular treatment of acute ischemic stroke. To investigate the use and embolectomy effect of Reco, the first embolectomy stent in China, in economically developed areas. Health economic assessment (cost-benefit analysis) of ischemic stroke patients in various regions of the province.

NCT ID: NCT05160610 Recruiting - Thrombolysis Rate Clinical Trials

Improving Thrombolysis Implementation Based on Electronic Monitoring in Acute Ischemic Stroke (ITEM)

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

A cluster randomized controlled trial will be conducted. Hospitals in Zhejiang Province, China, will be randomized into two arms (1:1): an intervention arm and a control arm. Hospitals in the intervention arm will receive a multilevel intervention based on the AACTT theory, whereas hospitals in the control arm will receive no intervention and maintain routine care. All the hospitals will receive electronic monitoring. Hospitals with no stroke center or with <20 cases received thrombolysis per year will be excluded from the study.

NCT ID: NCT05159947 Recruiting - Stroke, Acute Clinical Trials

SPT-07A Injection in Patients With Acute Ischemic Stroke (AIS): A Phase III Clinical Trial

SPAIR-2
Start date: January 20, 2022
Phase: Phase 3
Study type: Interventional

This is a multicenter, randomized, double-blind, placebo-controlled, parallel controlled clinical trial in Chinese patients with acute ischemic stroke. Objective to evaluate the efficacy and safety of SPT-07A injection compared with placebo in the treatment of patients with acute ischemic stroke.

NCT ID: NCT05156827 Withdrawn - Clinical trials for Acute Ischemic Stroke

A Study to Assess the Efficacy, Safety, and Pharmacokinetics of TB006 in Participants With Acute Ischemic Stroke

Start date: July 26, 2022
Phase: Phase 2
Study type: Interventional

This multi-center, randomized, parallel-group, double-blind, placebo-controlled study will evaluate the efficacy and safety of TB006 in participants with an Acute Ischemic Stroke (AIS) event with 57 days of treatment.

NCT ID: NCT05155540 Completed - Ischemic Stroke Clinical Trials

Direct Mechanical Thrombectomy Versus Bridging Therapy

Start date: July 1, 2019
Phase: Phase 4
Study type: Interventional

This study compares the efficacy and safety of direct mechanical thrombectomy versus bridging therapy in patients with anterior circulation large vessel occlusion in a cohort of patients treated at the stroke unit of a single centre at Alexandria University in Egypt.

NCT ID: NCT05154903 Recruiting - Clinical trials for Acute Ischemic Stroke

Citicoline in Ischemic Stroke

Start date: July 22, 2021
Phase: Phase 3
Study type: Interventional

There is evidence that citicoline is the only neuroprotectant able to improve the functional status of the patients after an acute ischemic stroke. Citicoline is a neuroprotectant drug against cerebral ischemia, with positive results, both in experimental and clinical trials, in the treatment of acute stroke and head injuries Also, the safety profile of citicoline is good, and there are no associated problems when the drug is used in this kind to patients The aim of this study is to confirm the efficacy and safety of citicoline in patients with moderate-to-severe acute ischemic stroke in Egypt, according to the characteristics of the medical care in this country

NCT ID: NCT05153655 Completed - Clinical trials for Acute Ischemic Stroke

Ischemic Post-conditioning in Acute Ischemic Stroke Thrombectomy

PROTECT
Start date: December 15, 2021
Phase: N/A
Study type: Interventional

Ischemic post-conditioning is a neuroprotective strategy that has been proven to attenuate reperfusion injury in animal models of stroke. The purpose of this proof-of-concept study is to determine the safety and tolerability of ischemic post-conditioning in patients with acute ischemic stroke who are treated with mechanical thrombectomy.

NCT ID: NCT05152524 Recruiting - Ischemic Stroke Clinical Trials

Distal Ischemic Stroke Treatment With Adjustable Low-profile Stentriever

DISTALS
Start date: March 25, 2022
Phase: N/A
Study type: Interventional

The objective of the DISTALS Study is to evaluate the safety and effectiveness of the Tigertriever 13 Revascularization Device in restoring blood flow in the neurovasculature by removing thrombus in patients presenting within 24 hours of onset with an ischemic stroke with disabling neurological deficits due to a primary distal vessel occlusion (DVO), as compared to medical management.

NCT ID: NCT05151263 Not yet recruiting - Ischemic Stroke Clinical Trials

Prevalence of Aspirin Resistance in Ischemic Stroke Patients at Assiut University Hospital

Start date: November 1, 2023
Phase:
Study type: Observational

- This study aims to assess the prevalence of aspirin resistance in patients with acute ischemic stroke and its importance in secondary stroke prevention. - Effect of aspirin resistance on short and long term mortality and detection of its relationship with recurrence of stroke.