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Ischemic Stroke clinical trials

View clinical trials related to Ischemic Stroke.

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NCT ID: NCT05842551 Recruiting - Stroke, Ischemic Clinical Trials

Prismatic Lenses and tDCS in Neglect

Start date: March 7, 2023
Phase: N/A
Study type: Interventional

The goal of this study is to to evaluate the effect and feasibility of a rehabilitation protocol with prismatic lenses associated with tDCS, compared to a prismatic lens rehabilitation protocol associated with sham stimulation, in reducing the signs of neglect in a group of patients with spatial heminegligence following ischemic stroke of the right hemisphere. The secondary objective is to evaluate the impact of this rehabilitation protocol on functional outcome.

NCT ID: NCT05842304 Recruiting - Stroke, Ischemic Clinical Trials

Individualized Precision rTMS for Language Recovery in Patients After Ischemic Stroke: a Multi-center RCT

Start date: June 5, 2023
Phase: N/A
Study type: Interventional

The current multi-center study aims to evaluate the efficacy and safety of pBFS-guided rTMS Neuromodulation Treatment for the rehabilitation of language functions in ischemic stroke aphasic patients.

NCT ID: NCT05838456 Completed - Clinical trials for Acute Ischemic Stroke (AIS)

Deep Learning Enabled Endovascular Stroke Therapy Screening in Community Hospitals

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

After onset of Acute Ischemic Stroke (AIS), every minute of delay to treatment reduces the likelihood of a good clinical outcome. A key delay occurs in the time between completion of computed tomography (CT) angiography of the head and neck and interpretation in the setting of AIS care. The purpose of this study is to assess the effect of incorporating Viz.AI software, which via via a machine-learning algorithm performs artificial intelligence-based automated detection of large vessel occlusions (LVO) on CT angiography (CTA) images and alerts the AIS care team (diagnosis and treatment decisions will be based on the clinical evaluation and review of the images by the treating physician, per routine standard of care). The hypothesis is that integration of the software into the AIS care pathway will reduce delays in treatment. A cluster-randomized stepped-wedge trial will be performed across 4 hospitals in the greater Houston area.

NCT ID: NCT05836766 Recruiting - Clinical trials for Acute Ischemic Stroke

Cilostazol Dexborneol Versus Placebo for Microcirculation Dysfunction After Reperfusion Therapy in Patients With Acute Ischemic Stroke With Large Vessel Occlusion

CRYSTAL
Start date: June 5, 2023
Phase: Phase 2
Study type: Interventional

This study aims to evaluate the efficacy of Y-6 sublingual tablets in improving microcirculation dysfunction and reducing thrombo-inflammation in patients who had AIS caused by LVO and received reperfusion therapy. Moreover, we expect to evaluate the safety of using Y-6 sublingual tablet in such study population.

NCT ID: NCT05836753 Recruiting - Clinical trials for Ischemic Stroke, Acute

Efficacy and Safety of Sarecycline in Patients With Acute Ischemic Stroke After Reperfusion Therapy

ESPRIT
Start date: May 7, 2023
Phase: Phase 2
Study type: Interventional

The aim of this study was to evaluate the efficacy and safety of Sarecycline versus placebo in the treatment of microcirculation dysfunction after reperfusion therapy in patients with large vessel occlusion stroke.

NCT ID: NCT05836740 Recruiting - Clinical trials for Ischemic Stroke, Acute

Efficacy and Safety of Minocycline in Patients With Moderate to Severe Acute Ischemic Stroke

EMPHASIS
Start date: May 19, 2023
Phase: Phase 3
Study type: Interventional

The aim of this study was to evaluate the efficacy and safety of Minocycline versus placebo in the treatment of patients with moderate to severe acute ischemic stroke.

NCT ID: NCT05833945 Active, not recruiting - Clinical trials for Stroke, Acute Ischemic

Potential Use of a POCT for the Direct Transfer of Stroke Patients From the Ambulance to the Thrombectomy Center

Start date: April 15, 2023
Phase:
Study type: Observational

Stroke is the leading cause of long-term disability and the second most common cause of death worldwide. Currently, the protocols require the imaging techniques at the hospitals to differ ischemic strokes with large vessel occlusion (LVO) from others. In this study, a duplex POC will be used in combination with an APP to identify LVO ischemic strokes in a 800 patients'cohort with pre-hospital and in-hospital blood samples.

NCT ID: NCT05833932 Recruiting - Ischemic Stroke Clinical Trials

Suhexiang Pill for Acute Ischemic Stroke: A Registry Study

SUNRISE
Start date: June 1, 2023
Phase:
Study type: Observational [Patient Registry]

The primary purpose of this study is to investigate the effectiveness and safety of the Suhexiang Pill for patients with acute ischemic stroke in real-world settings.

NCT ID: NCT05832762 Not yet recruiting - Clinical trials for Ischemic Stroke, Acute

Evaluation of Acute Endovascular Treatment in Symptomatic Isolated Cervical Internal Carotid Artery Occlusion Within 24 Hours of Last Seen Well (ETICA)

ETICA
Start date: June 1, 2023
Phase: N/A
Study type: Interventional

Our main hypothesis is that acute EVT associated with best medical treatment is superior to best medical treatment alone, for improving clinical outcomes at 90 days, in patient with mild or severe AIS and diffusion-perfusion or clinical-imaging mismatch, secondary to CICAO.

NCT ID: NCT05830175 Completed - Stroke Clinical Trials

The Effects Of Cervical Mobilization

CM
Start date: March 15, 2018
Phase: N/A
Study type: Interventional

The aim of this study is to examine the effects of cervical mobilization on balance and gait parameters in stroke individuals. Twenty-four stroke individuals aged 30-65 years, with a mini mental test score of 24 and above, and with a maximum score of 3 according to the modified rankin scale, were included in this study. Individuals were randomly divided into 2 groups as study (Bobath approach and cervical mobilization n=12) and control group (Bobath approach n=12). Demographic data, gait parameters, balance parameters and craniovertebral angle values of individuals were evaluated with clinical data evaluation form, Spatio-Temporal Gait Analysis (LEGSystm), Portable computerized kinesthetic balance device (SportKAT 550) and photometer, respectivelyThe evaluations were performed 2 times before and after the treatment.