Inflammation Clinical Trial
Official title:
The Effect of Intraradicular Cryotherapy on Post-operative Pain and the Level of Substance P in Patients With Symptomatic Apical Periodontitis
The aim of this clinical trial is to evaluate the effect of using intra-radicular cryotherapy technique in the form of irrigation with cold sodium hypochlorite The main questions to answer are: 1. Does Postoperative pain is different between the two groups? 2. Does level of substance P different between the two groups ?
- The patients will be randomly divided into three groups Group 1: control group (n=25) Regular root canal treatment with regular irrigant will be used. Group 2: (n=25) Intraradicular cryotherapy will be performed where : - Normal root canal treatment will be done with irrigation using sodium hypochlorite cooled to 4°C continuously during our mechanical instrumentation. Then a final flush will be done with cold saline 4°C for 5 minutes. Group 3: (n=25) Normal root canal treatment will be done with irrigation using sodium hypochlorite at room temperature during our mechanical instrumentation. Then a final flush will be done with cold saline 4°C for 5 minutes. ;
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