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Meniscus Lesion clinical trials

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NCT ID: NCT06376422 Recruiting - Meniscus Lesion Clinical Trials

Sterile Allogeneic Spongioflex® Allograft as Partial Meniscal Replacement After Incomplete Meniscal Loss

Start date: May 1, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to learn if partial meniscal replacement can prevent or postpone total meniscal replacement, in adult patients (female/male) with partial meniscal loss. The main questions it aims to answer are: - Can partial meniscal replacement improve knee function? - Can partial meniscal replacement prevent/postpone total meniscal replacement/knee prothesis? Researchers will compare the results of the operated group with patients not willing to be operated but with partial meniscal loss to see if the operation improves knee function. Participants will be operated and have to attend follow-up visits with MRI after 6 months up to 5 years after surgery.

NCT ID: NCT06319040 Completed - Clinical trials for Anterior Cruciate Ligament Injuries

The Effect Of Addıtıonal Surgery On Muscle Strength, Proprıoceptıon And Balance In Anterıor Crucıate Lıgament Surgery

Start date: December 6, 2018
Phase:
Study type: Observational

Meniscal tears and RAMP lesions are frequently seen together with ACL injuries. The aim of this study was to evaluate the effects of meniscus repair and RAMP lesion repair ACL reconstruction surgery in terms of muscle strength, proprioception, and balance. In our study, the clinical outcomes of both anterior cruciate ligament reconstruction (ACLR), medial meniscus repair (MR) and RAMP lesion repair (RR) have been compared with those of isolated ACLR.

NCT ID: NCT06159153 Recruiting - Meniscus Lesion Clinical Trials

Dynamic Ultrasonography VS MRI in the Evaluation of Meniscal Lesions in Patients With an Indication for Arthroscopy

Start date: November 9, 2023
Phase: N/A
Study type: Interventional

This is a diagnostic, open-label, single-center interventional study. This study aims to evaluate the diagnostic accuracy of dynamic ultrasonography for meniscal injuries in patients with an indication for arthroscopy, and to compare it with the study in MRI.

NCT ID: NCT05882591 Recruiting - Meniscus Tear Clinical Trials

Posteromedial Tibiofemoral Incongruence (PMTFI) Treatment

Start date: October 9, 2020
Phase: N/A
Study type: Interventional

The aim of this study is to assess outcomes of Posteromedial Tibiofemoral Incongruence (PMTFI) Treatment

NCT ID: NCT05655442 Withdrawn - Meniscus Lesion Clinical Trials

Arthroscopic Partial Meniscectomy Time Window

Start date: January 12, 2020
Phase: N/A
Study type: Interventional

The purpose was to assess knee function outcomes between early arthroscopic partial meniscectomy(APM) and delayed APM for patients with degenerative meniscus lesions(DMLs)

NCT ID: NCT05505747 Not yet recruiting - Meniscus Tear Clinical Trials

Enhancing Recovery Through a Combined Mechanobiologic Intervention Following Meniscus Repair

Start date: July 2025
Phase: Phase 2/Phase 3
Study type: Interventional

Arthroscopic meniscal procedures are the most commonly performed orthopaedic procedure in the U.S. affecting 15% of Americans ages 10-65 years. Meniscus injury is also known to increase the risk of posttraumatic osteoarthritis (PTOA). The current randomized clinical trial will test a novel intervention after meniscal repair that combines an oral senolytic fisetin and real-time biofeedback program to restore joint loading and subsequent return to activity.

NCT ID: NCT05433012 Terminated - ACL Injury Clinical Trials

Assessment Micro-anatomy of the Menisci and Cartilage After Isolated Acute ACL Injury With MRI at 7T

Start date: April 22, 2021
Phase: N/A
Study type: Interventional

Study population The investigator set the sample size to 200 patients. Primary outcome - Diagnostic accuracy of ultrahigh field MRI (T7) compared to high field MRI (T3 or less) for detection of meniscal injuries associated with acute ACL injury Secondary outcome - Influence of 1) Location of injury and 2) meniscal tear pattern (modified WORMS18,19) on the sensitivity of high field MRI compared to ultrahigh field MRI for detection of meniscal tears

NCT ID: NCT05370937 Completed - Meniscus Tear Clinical Trials

Clınıcal Results of Evelator and Free Knot Methods In Medial Menıscus Posterior Root Tears

Start date: October 16, 2021
Phase: N/A
Study type: Interventional

In this thesis study, the transtibial pullout method, which is one of the treatment methods for medial meniscus posterior root tear, will be used in patients over the age of 18 with medial meniscus posterior root tear, who applied to the Atatürk University Orthopedics and Traumatology clinic. The patients will be divided into two groups. In the first group, after knotting the posterior root of the medial meniscus with a fiber rope, a tunnel will be opened for the rope to pass through the medial of the proximal crest of the tibia. Then, arthroscopically, the rope will be taken through the joint and passed through the tunnel, and the knot will be fixed to the tibia by using the endobutton elevator system. In the second group, the first stage of fixation is the same, and fixation to the tibia will be done with an endobutton by tying a free knot without using an elevator system. The clinical and radiological scores of both groups just before the operation and at the twelve months after the operation will be calculated and their relationship with each other will be examined.

NCT ID: NCT05322005 Recruiting - Meniscus Tear Clinical Trials

Study of Clinical Performance and Safety of Treatments in Degenerative Meniscopathy With Injection of Polynucleotides

Start date: October 26, 2020
Phase: N/A
Study type: Interventional

This is a non-randomized multicentre study for the evaluation of the clinical performance and safaty of the augmentation-to-surgery and conservative treatments for the degenerative meniscopathies, with injection of polynucleotide gel.

NCT ID: NCT05261360 Recruiting - Knee Injuries Clinical Trials

Clinical Efficacy of Exosome in Degenerative Meniscal Injury

KNEEXO
Start date: March 2022
Phase: Phase 2
Study type: Interventional

Comparison of intra-articular administration of synovial fluid-derived mesenchymal stem cells-derived exosomes with synovial fluid-derived mesenchymal stem cells on the same patient.