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Investigating Micro-Manipulation Procedures for Assisted Hatching Timing — IMPACT  

Infertility Clinical Trial

Official title:
The IMPACT Trial: Investigating Micro-Manipulation Procedures for Assisted Hatching Timing

Clinical Trial Summary

This study aims to assess the clinical significance of cleavage stage (Day 3) assisted hatching compared to assisted hatching at the blastocyst stage (Day 5,6,7) of embryo development at the time of trophectoderm (TE) biopsy for patients undergoing in vitro fertilization (IVF) and preimplantation genetic testing for aneuploidy (PGT-A) for treatment of their infertility.

Clinical Trial Description

The proposed study aims to perform a split cohort study where each patient's cohort of fertilized zygotes, (two pronuclei or 2PNs) is split into two groups and randomized, thus allowing each patient to serve as their own control and decreasing confounding variables. Half of the cohort will proceed with the current standard of day 3 or cleavage assisted hatching and the other half of the cohort will receive the sequential hatching and trophectoderm biopsy procedure at the blastocyst stage of embryo development. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06377917
Study type Interventional
Source Reproductive Medicine Associates of New Jersey
Contact Christine V Whitehead, MS, BSN, RN
Phone 19736562841
Email clinicalresearchteam@ivirma.com
Status Not yet recruiting
Phase N/A
Start date May 2024
Completion date May 2026
View Details
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