Hypertension Clinical Trial
— iCaReMeOfficial title:
Real-world Multinational Registry to Determine Management and Quality of Care of Patients With Type 2 Diabetes, Hypertension, Heart Failure and/or Chronic Kidney Diseases
To provide real world data on patient characteristics, disease management, healthcare utilization, and outcomes in patients with type 2 diabetes, Hypertension, Heart failure and/or Chronic kidney diseases
Status | Recruiting |
Enrollment | 35000 |
Est. completion date | December 31, 2025 |
Est. primary completion date | December 31, 2025 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: 1. Being 18 years or older 2. Having type 2 diabetes, Hypertension, Heart Failure and/or chronic kidney disease 3. Providing written informed consent to participate in the registry Exclusion Criteria: 1. Having a life-threatening co-morbidity with life expectancy below 1 year 2. Participating in an interventional trial requiring informed consent |
Country | Name | City | State |
---|---|---|---|
Costa Rica | Research Site | Los Yoses | San José |
Ecuador | Research Site | Guayaquil | Guayas |
Ecuador | Research Site | Manta | Manabi |
Ecuador | Research Site | Quito | Pichincha |
Ecuador | Research Site | Quito | Pichincha |
Ecuador | Research Site | Quito | Pichincha |
Egypt | Research Site | Agouza | Giza |
Egypt | Research Site | Al Kasr Al Eini | Cairo |
Egypt | Research Site | El Matareya | Cairo |
Egypt | Research Site | El Nozha | Cairo |
Egypt | Research Site | Faisal | Giza |
Egypt | Research Site | Maadi | Cairo |
Egypt | Research Site | Ramses | Cairo |
Egypt | Research Site | Roxy | Cairo |
Ghana | Research Site | Kumasi | Ashanti Region |
Greece | Research Site | Attica | Athens |
Greece | Research Site | Attiki | Athens |
Greece | Research Site | Attiki | Athens |
Greece | Research Site | Attiki | Athens |
Greece | Research Site | Attiki | Athens |
Greece | Research Site | Attiki | Piraeus |
Greece | Research Site | Chalkidiki | Nea Moudania |
Greece | Research Site | Lamia | |
Greece | Research Site | Larissa | |
Greece | Research Site | Thessaloniki | |
Greece | Research Site | Thessaloniki | |
Greece | Research Site | Thessaloniki | |
India | Research Site | Gujarat | Ahmedabad |
Indonesia | Research Site | Jambi | Telanaipura |
Kenya | Research Site | Eldoret | |
Mexico | Research Site | Chihuahua | |
Mexico | Research Site | Jalisco | Guadalajara |
Mexico | Research Site | Jalisco | Guadalajara |
Mexico | Research Site | Jalisco | Guadalajara |
Mexico | Research Site | Jalisco | Guadalajara |
Mexico | Research Site | Jalisco | Guadalajara |
Mexico | Research Site | Jalisco | Guadalajara |
Mexico | Research Site | Nuevo Leon | Guadalupe |
Mexico | Research Site | Nuevo Leon | Monterrey |
Mexico | Research Site | Nuevo Leon | San Nicolás De Los Garza |
Mexico | Research Site | Queretaro | San Juan Del Río |
Nigeria | Research Site | Lagos | |
Peru | Research Site | Lima | |
Peru | Research Site | Lima | |
Peru | Research Site | Lima | |
Peru | Research Site | Lima | |
Philippines | Research Site | Antipolo | Rizal |
Philippines | Research Site | Cebu | |
Philippines | Research Site | Dasmarinas | Cavite |
Philippines | Research Site | Iloilo | |
Philippines | Research Site | Marikina | Metro Manila |
Philippines | Research Site | Pasig | Metro Manila |
South Africa | Research Site | Benoni | Johannesburg |
South Africa | Research Site | Durban | KwaZulu Natal |
Lead Sponsor | Collaborator |
---|---|
AstraZeneca |
Costa Rica, Ecuador, Egypt, Ghana, Greece, India, Indonesia, Kenya, Mexico, Nigeria, Peru, Philippines, South Africa,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | 1. Provide real world data on patient characteristics | Disease control (e.g. achievement of glycated hemoglobin target and incidence of hypoglycemic events) Management of micro- and/or macrovascular complications Management of associated risk factors (e.g. hypercholesterolemia and hypertension) Current diabetes, CKD and HF treatments Concomitant medications | Average of 3 years through study completion | |
Primary | 2. Provide real world data on disease management | Disease control (e.g. achievement of glycated hemoglobin target and incidence of hypoglycemic events) Management of micro- and/or macrovascular complications Management of associated risk factors (e.g. hypercholesterolemia and hypertension) Current diabetes treatments Concomitant medications | Average of 3 years through study completion | |
Primary | 3. Provide real world data on healthcare utilization | Number of diabetes, Chronic Kidney Disease(CKD) and Heart Failure(HF)-related visits to a physician not at study site Number of urgent care visits for diabetes Number of diabetes, CKD and HF-related hospital emergency department visits and reason(s) for visits Number of hospitalizations, lengths of stay, and reasons for hospitalizations | Average of 3 years through study completion | |
Primary | 4. Provide real world data on quality of care indicators | Smoking cessation Eye and foot examinations Dietary counselling | Average of 3 years through study completion | |
Primary | Provide real world data on cardiovascular outcomes in patients with type 2 diabetes; Chronic Kidney Disease and Heart Failure | All-cause and cause-specific deaths and hospitalizations, including recurrent events | Average of 3 years through study completion | |
Primary | 6. Provide real world data on renal outcomes and other microvascular complications in patients with type 2 diabetes and Heart Failure | All-cause and cause-specific deaths and hospitalizations, including recurrent events | Average of 3 years through study completion |
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