Saturated Fatty Acids Intake and Mortality, Diabetes, Hypertension and Overweight

Hypertension Clinical Trial

Official title:

Saturated Fatty Acids Intake and Mortality, Diabetes, Hypertension and Overweight in the China Health and Nutrition Survey (CHNS)

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03281512
• Other study ID #: Cohort_SFA
• Status: Completed
• Start date: January 1, 1989
• Est. completion date: December 31, 2012

Study information

• Verified date: March 2024
• Source: Zhejiang University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The role of saturated fatty acids (SFAs) intake in the development of total death, cardiovascular diseases, diabetes, hypertension and overweight are in great controversy but evidence from large population in China is scant.The investigators aim to use the data from the China Health and Nutrition Survey to assess the long-term association of SFAs intake with total mortality, diabetes, hypertension and overweight.

Description:

The role of saturated fatty acids (SFAs) intake in the development of total death, diabetes, hypertension and overweight are in great controversy but evidence from large population in China is lacking.The investigators aim to utilize the data from the China Health and Nutrition Survey. The investigators will calculate the cumulative average intake of SFAs based on 3 consecutive 24-h dietary recalls in each round.Sex-specific Cox regression models will be used to estimate the relative risk.Results from our work will be used to provide epidemiological evidence for improving recommendation on SFAs intake for Chinese in dietary guidelines.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 14383
• Est. completion date: December 31, 2012
• Est. primary completion date: December 31, 2011
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 20 Years and older

Eligibility

Inclusion Criteria:

• Adults aged =20 with complete data on diet and follow-up time

Exclusion Criteria:

• Cardiovascular diseases
• Diabetes (for analyses of diabetes)
• Body mass index = 24 kg/? (for analyses of overweight)
• Hypertension (for analyses of hypertension)

Related Conditions & MeSH terms

• Diabetes
• Diabetes Mellitus
• Hypertension
• Morality
• Overweight

Locations

Country	Name	City	State
n/a

Sponsors (2)

Lead Sponsor	Collaborator
Zhejiang University	National Institute of Health and Nutrition

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Mortality	Incidence of all-cause death, on basis of household members' report	From baseline until death or censoring on 31 December 2011, whichever came first, assessed up to an average of 10 years
Primary	Diabetes	Incidence of diabetes, on basis of self-reported physician diagnosis, fasting plasma glucose = 7.0 mmol/l or HbA1c = 6.5%	From entry into the study (baseline: 1997-2009) until 2011
Secondary	Saturated fatty acids intake	Cumulative average intake of saturated fatty acids on basis of 3 consecutive 24-h dietary recalls	From entry into the study (baseline: 1997-2009) until 2011
Secondary	Hypertension	Incidence of hypertension, on basis of self-reported physician diagnosis, systolic pressure = 140 mmHg or diastolic pressure = 90 mmHg	From entry into the study (baseline: 1997-2009) until 2011
Secondary	Overweight	Incidence of overweight, on basis of body mass index (BMI), BMI = 24 kg/?	From entry into the study (baseline: 1997-2009) until 2011