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Hyperlipidemias clinical trials

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NCT ID: NCT01406431 Completed - Hypertension Clinical Trials

Pharmacokinetic Study of Livalo® Fixed Combination Drug in Healthy Subjects

Start date: August 2011
Phase: Phase 1
Study type: Interventional

The purpose of this study is to compare pharmacokinetics between Pitavastatin and Valsartan co-administration and Livalo fixed combination drug in healthy male subjects.

NCT ID: NCT01402128 Completed - Clinical trials for Overweight; Hyperlipidemia

Efficacy and Safety of Fermented Barley on Decrement of Body Fat in Obese Subjects

Start date: June 2010
Phase: Phase 2/Phase 3
Study type: Interventional

Barley, like oats, is a rich source of the soluble fibre β-glucan, which has been shown to significantly lower LDL-cholesterol (LDL-C). However, barley foods have been less widely studied.

NCT ID: NCT01402102 Completed - Hyperlipidemia Clinical Trials

A Human Trial to Evaluate the Efficacy and Safety of Aged Garlic Powder on Improvement of Blood Lipids in Subjects With Hyperlipidemia

Start date: July 2010
Phase: Phase 2/Phase 3
Study type: Interventional

We performed a double-blind parallel study in a group of mildly hypercholesterolemic subjects who were given aged garlic powder over a period of 12 weeks. We measured serum lipids, including total cholesterol, low-density-lipoprotein (LDL) and high-density-lipoprotein (HDL) cholesterol, and triglycerides, and monitored their blood pressure.

NCT ID: NCT01393249 Completed - Clinical trials for Acute Lymphoblastic Leukemia

PEG-Asparaginase Associated Pancreatitis, Hepatotoxicity and Hyperlipidemia in Children With ALL

AAP2008
Start date: July 2011
Phase: N/A
Study type: Observational

The purpose of this study is to create a model enabling us to predict pancreatitis, hyperlipidemia and hepatotoxicity during treatment with PEG-Asparaginase in children with Acute Lymphoblastic Leukemia.

NCT ID: NCT01391585 Completed - Diabetes Clinical Trials

Expanding Comparative Effectiveness Research (CER) Capability Through Complex Patient Relationship Management

Start date: June 2011
Phase: N/A
Study type: Interventional

The investigators are testing whether patients with diabetes can communicate with our health care system through text messaging. The investigators will look at how often they respond to prompts for blood pressures, blood sugars, and step counts. The investigators will also see if they come in for lab tests when prompted by text message. Also, for patients overdue for medication refills, the investigators will ask them why they have not yet called for the refill.

NCT ID: NCT01388816 Completed - Clinical trials for Type II Hyperlipidemia

A Safety and Efficacy Study of DRL-17822, a Cholesteryl Ester Transfer Protein (CETP) Inhibitor, in Patients With Abnormal Cholesterol Levels

Start date: July 2011
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine if a new drug, DRL-17822, is safe and effective in elevating high density lipoprotein cholesterol (HDL-C) and reducing low density lipoprotein cholesterol (LDL-C) in people with abnormal cholesterol levels that may put them at risk for heart disease.

NCT ID: NCT01380730 Completed - Hyperlipidemia Clinical Trials

LAPLACE-TIMI 57: Low-density Lipoprotein Cholesterol (LDL-C) Assessment With PCSK9 monoclonaL Antibody Inhibition Combined With Statin thErapy

LAPLACE
Start date: July 1, 2011
Phase: Phase 2
Study type: Interventional

To evaluate the effect of 12 weeks of subcutaneous (SC) evolocumab (AMG 145) administered every 2 weeks (Q2W) or every 4 weeks (Q4W), compared with placebo, on percent change from baseline in LDL-C when used in addition to a statin in adults with hypercholesterolemia.

NCT ID: NCT01377064 Completed - Obesity Clinical Trials

Home-based Exercise for Management of HIV-associated Cardiovascular Disease Risk

Start date: March 2011
Phase: Phase 1
Study type: Interventional

Because of advances in drug treatment, people living with HIV/AIDS (PLWHA) are living longer, but are also at greater risk for cardiovascular disease (CVD) and diabetes. Exercise and increased physical activity can reduce the risk factors for these diseases in PLWHA, but no studies have tested an at-home exercise program that would benefit low income people and others who do not have access to exercise facilities. This study will test the feasibility of an at-home exercise program for PLWHA and prepare for a full-scale intervention study, which may lead to a reduction in CVD risk among PLWHA.

NCT ID: NCT01375777 Completed - Hyperlipidemia Clinical Trials

Monoclonal Antibody Against PCSK9 to Reduce Elevated Low-density Lipoprotein Cholesterol (LDL-C) in Adults Currently Not Receiving Drug Therapy for Easing Lipid Levels

MENDEL
Start date: July 6, 2011
Phase: Phase 2
Study type: Interventional

The primary objective was to evaluate the effect of 12 weeks of subcutaneous evolocumab (AMG 145) every 2 weeks (Q2W) or every 4 weeks (Q4W), compared with placebo, on the percent change from baseline in LDL-C when used as monotherapy in adults with hypercholesterolemia.

NCT ID: NCT01375764 Completed - Hyperlipidemia Clinical Trials

Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects

GAUSS
Start date: July 28, 2011
Phase: Phase 2
Study type: Interventional

The primary objective was to evaluate the effect of 12 weeks of subcutaneous evolocumab (AMG 145), compared with ezetimibe, on percent change from baseline in low-density lipoprotein cholesterol (LDL-C) in patients with hypercholesterolemia unable to tolerate an effective dose of a statin.