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Hyperlipidemias clinical trials

View clinical trials related to Hyperlipidemias.

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NCT ID: NCT06225635 Completed - Hyperlipidemias Clinical Trials

A Phase 1 Study to Evaluate the Safety and Pharmacokinetics of Ezerosu Tab

Start date: January 1, 2022
Phase: Phase 1
Study type: Interventional

A Phase 1 Study to Evaluate the Safety and Pharmacokinetics of Ezerosu Tab

NCT ID: NCT06190587 Completed - Healthy Clinical Trials

Effect of Goji Berry Consumption on Biochemical Parameters

Start date: May 15, 2022
Phase: N/A
Study type: Interventional

Goji Berry as a functional food have been shown to reduce risk of hyperlipidemia, type 2 diabetes, etc. However, human studies are limited in this area. In this study, it has been aimed to evaluate the effect of goji berry consumption on some biochemical parameters in healthy individuals.

NCT ID: NCT06163443 Completed - Clinical trials for Hyperhomocysteinemia

Evaluating the Impact of B Vitamin Supplementation (Soloways™) on Homocysteine and LDL-C Levels in Patients With MTHFR, MTR, and MTRR Polymorphisms.

VITAGEN-H
Start date: March 2, 2022
Phase: N/A
Study type: Interventional

This randomized, double-blind, placebo-controlled trial will evaluate the impact of methylfolate, pyridoxal-5'-phosphate (P5P), and methylcobalamin supplementation on homocysteine and LDL-C levels in individuals with low to medium cardiac risk and MTHFR, MTR, and MTRR gene polymorphisms. The study aims to explore the efficacy of these vitamins in reducing homocysteine levels, a critical risk factor for cardiovascular disease (CVD), while also monitoring LDL-C levels. The findings will offer valuable insights into personalized CVD prevention and management, emphasizing the significance of genetic factors in nutritional therapy.

NCT ID: NCT06154408 Completed - Clinical trials for LDL Hyperlipoproteinemia

Evaluating the Impact of Omega-3 Fatty Acid Supplementation (Soloways™) on Lipid Profiles in Adults With PPARG Polymorphisms

SOLIPARG
Start date: February 10, 2022
Phase: N/A
Study type: Interventional

In this study, 102 patients will be evenly randomized into two groups: one set to receive omega-3 fatty acids and the other a placebo. The process will be blinded, ensuring that neither the researchers nor the participants will know which group they are in. Each participant will take two capsules daily for a duration of 90 days, with the active group receiving capsules containing 1000 mg of fish oil each. All participants will be instructed to maintain their usual diet, lifestyle, and medication regimen. At the beginning and end of the study, various health assessments, including lipid panels and C-reactive protein measurements, will be conducted. Additionally, DNA samples will be collected for genotyping to identify patients with specific PPARG gene polymorphisms, leading to the creation of four distinct subgroups: those receiving omega-3 with and without polymorphisms, and those receiving placebo with and without polymorphisms.

NCT ID: NCT06053788 Completed - Hyperlipidemias Clinical Trials

PocDoc Lipids Usability Study for Self-test Use

Start date: April 26, 2023
Phase: N/A
Study type: Interventional

This study seeks to expand the approved indication of use for a UKCA approved IVD device. PocDoc lipids is approved for professional use to measure the levels of lipids in a fingerprick blood samples. This study will investigate the usability of the device by untrained lay people in order to expand the device's utility to the self-test setting.

NCT ID: NCT06002893 Completed - Hyperlipidemia Clinical Trials

The Antihypercholestrolemic Effect of a Combined Nutritional Supplementation of Standardized Extracts of Amla, Walnut, Red Yeast Rice and Olive

Start date: March 19, 2020
Phase: N/A
Study type: Interventional

Nutraceutical lipid-lowering interventions are becoming increasingly popular, particularly among patients who are intolerant or refractory to prescription statins, or who desire alternative non-conventional pharmacological treatment to manage their dyslipidaemia, whether they previously experienced statin intolerance or not. A growing body of preclinical and clinical evidence suggest that the amla (Emblica officinalis) red yeast rice (RYR), olive and walnut leaf extracts posses consideable hpolipidaemic pharmacological effects.

NCT ID: NCT05858372 Completed - Clinical trials for Hypercholesterolemia

Effects of Chios Mastiha Essential Oil on Cholesterol Levels of Healthy Volunteers

MASTIHA-OIL
Start date: July 1, 2022
Phase: N/A
Study type: Interventional

A prospective, randomized, placebo-controlled study was designed to study the hypolipidemic effect of CMO capsules on healthy volunteers with elevated cholesterol levels.

NCT ID: NCT05825963 Completed - Obesity Clinical Trials

Psyllium-enriched Hamburger Meatballs: Effects on Postprandial Lipidemia, Glycemia, Appetite, and Food Intake

Start date: April 12, 2022
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to enrich the hamburger meatball with psyllium without impairing its sensory properties and to investigate the effects on acute postprandial lipemia and glycemia, prospective food intake, and some appetite indicators in healthy adults. The main hypotheses of the study are: 1. There is no difference in sensory analysis results between hamburger meatballs enriched with psyllium and those that are not enriched. 2. The rise in postprandial lipids after consuming psyllium-enriched hamburger meatballs is lower than that of classic hamburgers. 3. The rise in postprandial glycemia after consuming psyllium-enriched hamburger meatballs is lower than that of classic hamburgers. 4. The feeling of satiety after consuming psyllium-enriched hamburger meatballs lasts longer, and the feeling of hunger lasts for a shorter period compared to classic hamburgers. 5. Daily food intake after consuming psyllium-enriched hamburger meatballs is less than that of classic hamburgers. Participants will, - Eat hamburgers, after fasting for 12 hours, with psyllium-enriched and classic meatballs on intervention days. - Keep a record of their food intake for the previous and following 24 hours of each intervention. - Be given fasting and postprandial blood samples. - Evaluate their hunger and satiety levels on a 100 mm horizontal visual analog scale (VAS) at the beginning and every hour for the following 6 hours of the study.

NCT ID: NCT05742022 Completed - Clinical trials for Combined Hyperlipidemia

"Phospholipovit" vs Placebo in Patients With Combined Hyperlipidemia

Start date: January 1, 2016
Phase: Phase 2/Phase 3
Study type: Interventional

"Phospholipovit" vs placebo in patients with combined hyperlipidemia

NCT ID: NCT05729659 Completed - Oxidative Stress Clinical Trials

Sideritis Supplementation, Oxidative Stress and Health

Start date: February 15, 2023
Phase: N/A
Study type: Interventional

The aim of the present clinical study is to estimate the efficacy of a Sideritis Scardica extract (SidTea+), derived from the Greek mountain Taygetos, in regulating antioxidant and health biomarkers in healthy adults.