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HIV clinical trials

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NCT ID: NCT04296292 Completed - HIV Clinical Trials

The Lived Experience of Participants in an African Randomised Trial

LEOPARD
Start date: February 5, 2020
Phase:
Study type: Observational

There has been no previous qualitative study conducted in a low-income setting which has aimed to explore the experience of individuals who enrol into a clinical trial for the management of a life-threatening illness. The investigators plan to collect data from trial participants, their next-of-kin, and researchers working on a multi-site randomised controlled trial for the treatment of HIV-associated cryptococcal meningitis.

NCT ID: NCT04292002 Completed - HIV Clinical Trials

Test@Work Study: Evaluation of Attitudes and Uptake Within Employee Health Checks in the Construction Industry

Test@Work
Start date: August 17, 2019
Phase: N/A
Study type: Interventional

This project is called Test@Work. In this project the investigators will offer general health checks and tailored health advice to up to 650 employees in the construction industry at sites across the East Midlands. The investigators will assess reach and uptake, and evaluate the views and perceptions of employees, managers and the delivery team. Health checks will include Body Mass Index (BMI; weight/height), waist-to-hip ratio, blood pressure, mental health screen, sexual health consultation and an opt-in rapid screening test for human immunodeficiency virus (HIV). Employees will be provided with a resource pack with information and signposting around physical activity, diabetes risk, diet, and musculoskeletal health. A digital resource providing information and signposting about workplace health screening and HIV testing will be developed and provided to managers at the participating worksites 2 weeks before their health check event. Employees will be offered an additional text messaging service involving receipt of a series of messages with advice around HIV and testing alongside general health information. Employees will complete post-health check exit questionnaires and an exit interview. Managers will complete a post-event evaluation questionnaire and post-event interview. Mixed-methods evaluation will include assessment of reach, uptake, and intervention implementation processes.

NCT ID: NCT04286347 Terminated - Hiv Clinical Trials

HCV, HBV, HIV Testing During Consultation With Anesthesiologist

SAHARA
Start date: August 5, 2021
Phase: N/A
Study type: Interventional

The aim of the study is to assess the feasibility of HCV, HBV, HIV testing (according to the national guidelines) during consultation with Anesthesiologist before a planned surgery in Lariboisiere Hospital, Paris, France. The feasibility will be the number of tested patients divided by the number of patients who should have been tested according to the national guidelines (for each virus).

NCT ID: NCT04286282 Completed - Depression Clinical Trials

Neuroinflammation and Modulating Factors in Depression and HIV

Start date: February 1, 2021
Phase: Phase 2
Study type: Interventional

Determine if depression, which persists after depression treatment at 26 weeks, is associated with increased innate inflammation in a prospective cohort of HIV-infected Ugandans receiving SSRIs in which group psychotherapy is initiated.

NCT ID: NCT04275310 Terminated - Hiv Clinical Trials

Microeconomic Intervention to Reduce HIV Transmission in Economically Disadvantaged Transgender Women

Start date: July 20, 2022
Phase: N/A
Study type: Interventional

The purpose of this research study is to learn more about the economic situations, discrimination experiences, and risk behaviors of transgender women. The ultimate purpose of the study is to test an intervention to improve financial conditions and reduce HIV risk behaviors in transgender women.

NCT ID: NCT04240691 Active, not recruiting - HIV Infections Clinical Trials

Instacare - Rapid ART Initiation Among Persons With HIV and Out of Care

Start date: May 20, 2020
Phase:
Study type: Observational

This study aims to evaluate two ways to help people re-engage with healthcare. The first is to assess if providing HIV treatment on the first visit (or within 1 week) can help people re-engage with care and ultimately stay in care after 24 and 48 weeks. It will also assess the success of starting treatment immediately by measuring the HIV virus in people's bloodstream after 24 and 48 weeks. The second part of this study is to assess a new behavioral treatment called 60-Minutes-for-Health which aims to help people identify and overcome barriers to HIV care, to help with motivation maintaining in care, to help cope with negative feelings about HIV, and to help increase self-reliance in seeking healthcare amid other things that are happening in your life.

NCT ID: NCT04233931 Completed - Hiv Clinical Trials

Mhealth for Pre-exposure Prophylaxis Adherence by Young Adult MSM

Start date: June 21, 2017
Phase: N/A
Study type: Interventional

The proposed project involves the development and testing of an mhealth intervention to increase adherence to PrEP treatment using texts providing tailored pill reminders, motivational messages, and health education messages. The intervention targets culturally-diverse young adult men who have sex with men (YMSM), who are at high risk for both HIV and non-adherence to PrEP medication. Supporting PrEP adherence would help reduce new HIV infections in this group.

NCT ID: NCT04233372 Recruiting - Hiv Clinical Trials

Evaluation of (Doravirine / Lamivudine / Tenofovir Disoproxil Fumarate) (Delstrigo®) as a New Strategy for Non-occupational Post Exposure Prophylaxis, a Prospective Open Label Study

DORAVIPEP
Start date: August 27, 2020
Phase: Phase 4
Study type: Interventional

Subjects who go to emergency room for possible contact to HIV transmission receive Delstrigo as post exposition prophylaxis.

NCT ID: NCT04230395 Recruiting - Hiv Clinical Trials

Alcohol Reduction Among People With TB and HIV in India

HATHI
Start date: September 22, 2022
Phase: N/A
Study type: Interventional

The highest incidence of tuberculosis disease (TB) in the world is in India, accounting for 27% of all new cases globally, with approximately 86,000 among persons with HIV (PWH). Unhealthy alcohol use can worsen the health of people who have Tuberculosis (TB) and people who have both TB and HIV. Behavioral interventions that 1) target alcohol use and 2) are integrated into TB and TB/HIV care may lead to better outcomes. The goal of this study is to test if a behavioral alcohol reduction intervention integrated into TB treatment can reduce alcohol use and improve TB and HIV health outcomes among people with unhealthy alcohol use. The aims of the HATHI study are: Aim 1: To test if a 4 session behavioral alcohol reduction intervention, called CAP (Counseling on Alcohol Problems), integrated into TB and TB/HIV Care can decrease unhealthy alcohol use among persons with TB and TB and HIV. Aim 2: To test if the CAP intervention, integrated into TB and TB/HIV care can improve TB and HIV clinical outcomes; Aim 3: To evaluate barriers and facilitators to integrating CAP into TB and TB/HIV care, and to determine the incremental costs of delivering CAP in TB and HIV clinical settings. Investigators hypothesize that CAP intervention will reduce alcohol use among persons with TB and TB with HIV, and that it delivery in the TB and TB/HIV setting will be acceptable to patient and providers and feasible.

NCT ID: NCT04225832 Recruiting - HIV Clinical Trials

A Cognitive Behavioral Therapy Group Intervention to Increase HIV Testing and PrEP Use Among Latinx Sexual Minority Men

Start date: January 20, 2020
Phase: N/A
Study type: Interventional

This study consists of a randomized controlled trial (RCT) of a multi-session cognitive behavior therapy (CBT) group intervention that aims to improve HIV outcomes by increasing adaptive, effective coping responses to stigma from intersectional identities related to ethnicity, immigration status, sexual minority identity, HIV status, and PrEP use among Latinx sexual minority men (SMM).