Syringe Service Based Telemedicine and Social Network Driven HIV Prevention Service Implementation

HIV Infections Clinical Trial

Official title: Syringe Service Based Telemedicine and Social Network Driven HIV Prevention Service Implementation

Status Not yet recruiting

Clinical Trial Summary

The goal of this clinical trial is to evaluate the effectiveness of a social network intervention to recruit people who inject drugs and their networks for HIV testing and linkage to HIV prevention and treatment services in Maryland. Study aims are to determine the effectiveness of a social network driven intervention to increase:

• HIV testing (primary);

• PrEP knowledge;

• Uptake of HIV services and pre-exposure prophylaxis (PrEP);

• Uptake of medication for opioid use disorder (MOUD) initiation.

Eligible participants who access syringe service programs (SSPs) serving two counties in Maryland and their risk network members (NMs) will be recruited using an established network inventory and coupon recruitment method. When an index successfully recruits NMs, the index-NM cluster will be randomized to either a peer-educator intervention arm or an equal-attention control arm. Index participants randomized to the peer-educator intervention arm will complete a training program adapted with stakeholder input to context that emphasizes effective communication, frequent HIV testing, and awareness of evidence-based HIV prevention and treatment services. An important innovation to the network intervention will be training indexes to use and distribute HIV self-test kits and naloxone to their NMs. Index participants randomized to the equal-attention control arm will receive training sessions focused on the opioid overdose epidemic and will not include any training to serve as a peer educator. All participants (indexes and NMs) will complete study assessments at baseline and at 3 and 9 months. We will compare the peer-educator intervention group and the equal-attention control group on rates of HIV testing, knowledge of PrEP options and resources, and rates of initiation of HIV treatment, PrEP, and MOUD treatment since the previous assessment (past 3 or 6 months).

Clinical Trial Description

n/a

Related Conditions & MeSH terms

• Addiction
• Drug Use
• HIV Infections
• Intravenous Drug Usage
• Opioid Use
• Substance Use Disorders
• Substance-Related Disorders

• NCT number: NCT06103370
• Study type: Interventional
• Source: Johns Hopkins University
• Contact: Oluwaseun Falade-Nwulia, MBBS, MPH
• Phone: 410-550-6234
• Email: ofalade1@jhmi.edu
• Status: Not yet recruiting
• Phase: N/A
• Start date: August 2024
• Completion date: November 2028