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Hemorrhage clinical trials

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NCT ID: NCT05604430 Enrolling by invitation - Heart Failure Clinical Trials

Pre-hospital Ventilation Clinical Study

Start date: June 30, 2022
Phase:
Study type: Observational

This study will collect and characterize ventilator use during patient care with a ZOLL 731 Series ventilator in a pre-hospital setting.

NCT ID: NCT05499806 Enrolling by invitation - Clinical trials for Traumatic Brain Injury

Cohort Study on the Effects of Aging in Acquired Brain Injury Patients

BRAINReADAPT
Start date: March 18, 2022
Phase:
Study type: Observational [Patient Registry]

A prospective cohort study (questionnaires), with an embedded case control study (neuropsychological assessments) in which the data is gathered within a timeframe of 3 years. A group of 700 patients and a group of 100 healthy volunteers will be participating.

NCT ID: NCT05312658 Enrolling by invitation - Anemia Clinical Trials

Aortic Compression Trial to Reduce Blood Loss at Cesarean Section

ACT
Start date: December 1, 2022
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to test if manual external aortic compression can prevent heavy blood loss in cesarean section. The main question[s] it aims to answer are: 1. Is external aortic compression safe? 2. Is external aortic compression effective? Participants will receive preventive external aortic compression or no external aortic compression right after the baby is out at cesarean section. Blood loss will be measured, as well as kidney function, hemoglobin, and hematocrit before and after the operation. Experienced discomfort will be assessed the day after surgery and breastfeeding and signs of depression will be assessed using questionnaires after 2 months. Researchers will compare women with and without external aortic compression to see if there are differences in these outcomes.

NCT ID: NCT05302661 Enrolling by invitation - Liver Cirrhosis Clinical Trials

Effect of Re-education on Rebleeding Rate After Endoscopic Treatment in Liver Cirrhosis

Start date: February 19, 2022
Phase: N/A
Study type: Interventional

A prospective, randomized controlled study on whether re-education after discharge can reduce the rebleeding rate after endoscopic treatment of esophageal and gastric varices in patients with liver cirrhosis

NCT ID: NCT05230134 Enrolling by invitation - Anesthesia, Local Clinical Trials

Cervical Sympathetic Block in Patients With Cerebral Vasospasm

Start date: July 27, 2023
Phase: N/A
Study type: Interventional

The purposes of this study are twofold: 1) to assess the effect of a cervical sympathetic block on cerebral blood flow in patients suffering from cerebral vasospasm, after aneurysmal subarachnoid hemorrhage; 2) to evaluate the effect of the sympathetic block on the recovery of the neurological function.

NCT ID: NCT05110482 Enrolling by invitation - Clinical trials for Adverse Effect of Oxytocic Drugs

Carbetocin Versus Syntocinon for Prevention of Postpartum Hemorrhage in Cardiac Patients Undergoing Caesarean Section

Start date: November 30, 2021
Phase: Phase 4
Study type: Interventional

Postpartum hemorrhage (PPH) is the primary cause of nearly one quarter of all maternal deaths globally. Management of uterine tone after delivery involves giving a prophylactic uterotonic and the use of controlled cord traction to facilitate delivery of the placenta and minimize blood loss. Syntocinon and carbetocin are the most commonly used drugs ,During caesarean delivery of stenotic valvular disease patient, the anesthesiologist have an important question: what is the best drug used for prevention of PPH with minimal hemodynamic effect regarding Systemic vascular resistance (SVR), Cardiac out put (COP),Heart rate ( HR), blood pressure? As uterotonic drugs may cause severe hypotension, decrease in SVR and COP that may not be tolerated by these patients .this thesis aims to compare between syntocinon and carbetocin regarding their effect on cardiac output and systemic vascular resistance using cardiometry in cardiac patients with stenotic lesions during caesarean delivery.

NCT ID: NCT04733638 Enrolling by invitation - Clinical trials for Intracerebral Hemorrhage

ADVANCE- Automated Detection and Volumetric Assessment of ICH

Start date: January 26, 2021
Phase:
Study type: Observational

To evaluate the performance of the Viz ICH VOLUME algorithm.

NCT ID: NCT04467996 Enrolling by invitation - Clinical trials for Postpartum Hemorrhage, Immediate

Minimum Effective Duration of Intrauterine Balloon Tamponade for the Management of Postpartum Hemorrhage

Start date: October 19, 2020
Phase: N/A
Study type: Interventional

Intrauterine balloon tamponade (IUBT) is recommended worldwide as the second-line therapy to treat postpartum hemorrhage. While much literature demonstrates the effectiveness of this therapy, little is known about how long the IUBT should be used once placed. Though it is common to use IUBT for 12-24 hours, the balloon may be equally effective when used for shorter durations of time, which could have beneficial effects for patients and hospitals. The proposed study is a pragmatic randomized controlled trial of non-inferiority comparing two durations of time for intrauterine balloon tamponade placement, 6 and 18 hours, in controlling postpartum hemorrhage. The specific aims of the proposed study are to determine: 1) whether quantitative blood loss significantly differs when the balloon is removed in 6 hours compared to 18 hours, 2) whether hemorrhage-related morbidity differs when the IUBT is kept in place for 6 or 18 hours, and 3) whether shorter duration of IUBT placement has beneficial effects including shortened postpartum hospital stays, improved maternal-infant bonding, and reduced postpartum pain prior to maternal discharge from hospital. We hypothesize that, once hemorrhage control has been achieved with IUBT placement, there is no clinically significant difference in postpartum blood loss when the balloon is removed 6 hours after placement compared to 18 hours after placement.

NCT ID: NCT03865979 Enrolling by invitation - Clinical trials for Intracerebral Hemorrhage

AI ENRICH - AI Detection of ICH

Start date: January 23, 2020
Phase: N/A
Study type: Interventional

To evaluate the performance of the Viz RECRUIT software in subjects identified as symptomatic of a stroke event as determined by standard of care imaging assessments and interpretation.

NCT ID: NCT03538379 Enrolling by invitation - Hemorrhage Clinical Trials

Tourniquet Training Effectiveness Study

TRIAGE
Start date: April 4, 2018
Phase: N/A
Study type: Interventional

Trauma is the leading cause of death for individuals ages 1-45 years old, within this cohort, and uncontrolled hemorrhage is the leading cause of preventable death.1,2 Tourniquets have been shown to be effective in dramatically decreasing death from uncontrolled hemorrhage on the battlefield and there is level 4 evidence that EMS application of tourniquets in the civilian sector is effective though not to the same degree as in the military.3,4 Multiple national groups have advocated that to further decrease preventable deaths from hemorrhage, laypersons should apply tourniquets before the arrival of professional first responders. To this aim, the "Stop the Bleed" campaign has trained over 100,000 individuals in the US in hemorrhage control techniques and tourniquet use with the Bleeding Control Basic (B-Con) course.5 The "Stop the Bleed" campaign informs course participants all commercial tourniquets are equivalent, and improvised tourniquets should be applied if a commercial tourniquet is not available.6 The investigators are evaluating the ability of the B-Con course participants to apply three different types of commercial tourniquets, the Rapid Application tourniquet (RAT), the Stretch-Wrap-And-Tuck tourniquet (SWAT-T), and the Sof Tourniquet (Sof-T) as well as participants ability to fashion an improvised tourniquet. The investigators hypothesize B-Con in its current form does not enable course participants to apply other commercial tourniquets beyond the specific one taught, the CAT tourniquet, and does not teach how to apply an improvised tourniquet.