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Hemorrhage clinical trials

View clinical trials related to Hemorrhage.

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NCT ID: NCT03129009 Recruiting - Clinical trials for Intracerebral Hemorrhage

Hemodynamics and Vital Organ Function in Intracerebral Hemorrhage

Start date: April 1, 2017
Phase: N/A
Study type: Interventional

Spontaneous non-traumatic intracerebral hemorrhage (ICH) is a common symptom in clinical practice and is the most serious among all types of stroke.Recently, as a relatively mainstream and recognized INTERACT2 (five well-known international studies in the cerebrovascular field: IMS-III, MR RESCUE, SYNTHESIS EXPANSION, INTERACT2, CHANCE) studies have shown that in patients with standard systolic blood pressure Early intensive antihypertensive therapy does not increase the incidence of death or serious adverse events. The above studies confirm the safety and efficacy of early potent depression.In 2017, Anesthesiology published a META analysis of intraoperative hypotension and blood pressure versus baseline fluctuations. The final outcome showed that 20% of blood pressure in the study was similar to MAP <65 mmHg, regardless of the duration of the duration There will be postoperative myocardial and renal damage. Ischemia is a very important cause of organ damage. Myocardial injury is closely related to the level of mean arterial pressure, while ischemia and ischemic reperfusion injury are closely related to postoperative acute renal injury.There is no targeted guideline for ICH perioperative blood pressure management, especially intraoperative blood pressure management, and no previous studies have studied most of the studies involving ICH patients with conservative treatment, ICH patients with surgical treatment There are few reports on blood pressure control during surgery.

NCT ID: NCT03128866 Recruiting - Pelvic Mass Clinical Trials

Tranexamic Acid in Reducing Blood Loss in Patients With Pelvic Tumors Undergoing Hemipelvectomy Surgery

Start date: May 19, 2017
Phase: Early Phase 1
Study type: Interventional

This early phase I trial studies how well tranexamic acid works in reducing the loss of blood in patients with pelvic tumors undergoing hemipelvectomy surgery. Tranexamic acid decreases blood loss by stabilizing clots and preventing clot lysis in patients undergoing surgery.

NCT ID: NCT03126968 Completed - Bleeding Clinical Trials

Prophylactic Topical Epinephrine to Reduce Bleeding in Transbronchial Lung Biopsies

PROPHET
Start date: July 1, 2017
Phase: Phase 2/Phase 3
Study type: Interventional

Bleeding poses potential for significant complication after transbronchial lung biopsies. The investigators hypothesize that prophylactic intrabronchial instillation of topical epinephrine will reduce the likelihood of bleeding. The investigators plan a double-blind, placebo controlled trial to evaluate this hypothesis.

NCT ID: NCT03125551 Withdrawn - Dietary Supplements Clinical Trials

ROTEM and Dietary Supplements

Start date: June 2017
Phase: N/A
Study type: Interventional

Dietary Supplements can affect platelet activation and aggregation, which could result in bleeding tendencies. This study wishes to evaluate the influence that these supplements has on platelet function using Rotational thromboelastometry.

NCT ID: NCT03124030 Recruiting - Dental Diseases Clinical Trials

Intra- and Post- Operative Bleeding After Simple Dental Extraction in Direct Oral Anticoagulant Therapy

NOADB
Start date: August 2, 2016
Phase: N/A
Study type: Observational

Direct Oral Anticoagulants were recently approved for medical treatment of several condition such as, non valvular atrial fibrillation, deep venous thrombosis, and others, substituting sometimes the conventional oral anticoagulants. The aim of the present study is to observe the possible difference in intra-operative and post-operative bleeding events for single dental extraction.

NCT ID: NCT03124004 Recruiting - Clinical trials for Periodontal Diseases

Evaluation of the Intra- and Post- Operative Bleeding After Periodontal Debridement in Direct Anticoagulant Patients

NOADB_db
Start date: August 15, 2016
Phase: N/A
Study type: Observational

Direct Oral Anticoagulants were recently approved for medical treatment of several condition such as, non valvular atrial fibrillation, deep venous thrombosis, and others, substituting sometimes the conventional oral anticoagulants. The aim of the present study is to observe the possible difference in intra-operative and post-operative bleeding events for periodontal debridement.

NCT ID: NCT03121898 Completed - Bleeding Clinical Trials

PLATelet Function Operating Room Monitoring

PLATFORM
Start date: February 1, 2017
Phase:
Study type: Observational

Prospective cohort study on adult cardiac surgery patients. Platelet function evaluated before and after cardiopulmonary bypass. Bleeding and transfusion recorded. Primary endpoint is finding the association between postoperative platelet function and bleeding.

NCT ID: NCT03120208 Recruiting - Clinical trials for Postpartum Depression

Prevalence of Psychological Disorders After Immediate Postpartum Hemorrhage

PSYCHE
Start date: April 27, 2017
Phase: N/A
Study type: Interventional

The objective of this cross-sectional study is to assess the prevalence of depression at 2 months, 6 months, and 1 year postpartum in women who had an immediate postpartum hemorrhage (immediate PPH defined as blood loss ≥ 500 mL within 24 hours of delivery). The potential serious consequences of PPH may lead to a greater number of psychological disorders in these women than in women without PPH.

NCT ID: NCT03119987 Completed - Clinical trials for Gastrointestinal Hemorrhage

Predictive Role of Red Cell Distribution Width in Upper GI Bleeding Patients

Start date: January 1, 2011
Phase: N/A
Study type: Observational

Acute upper-gastrointestinal bleeding (UGIB) is a commonly encountered cause of admission in emergency department (ED). Early risk stratification allows appropriate therapy that may be helpful to advance the patient's morbidity and mortality. Investigators hypothesized that early RDW levels may have an independent, linear relationship with recurrent or massive bleeding in UGIB patients.

NCT ID: NCT03118895 Completed - Clinical trials for Myocardial Infarction

Leaders Free III: BioFreedom™ Clinical Trial

Start date: November 8, 2017
Phase: N/A
Study type: Interventional

A study evaluating the safety and efficacy of the BioFreedom™ Biolimus A9™ coated Cobalt Chromium coronary stent system in patients at high risk of bleeding