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Hemolysis clinical trials

View clinical trials related to Hemolysis.

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NCT ID: NCT06391502 Recruiting - Ischemic Stroke Clinical Trials

Vivifrail Program on the Degree of Debilitation in Hospitalized Patients After Venous Hemolysis in Acute Ischemic Stroke

Start date: August 1, 2024
Phase: N/A
Study type: Interventional

Physical exercise is an effective strategy to maintain functional ability and improve debilitating symptoms in the elderly.In addition to functional enhancement, exercise is considered a cornerstone for enhancing cognitive function in debilitated older adults with cognitive impairment and dementia.The investigators evaluated the effect of the Vivifrail exercise intervention on the degree of debilitation in elderly hospitalized patients after venous hemolysis in acute ischemic stroke

NCT ID: NCT06389474 Not yet recruiting - Clinical trials for Hemolytic-Uremic Syndrome

A Phase III Study to Evaluate the Efficacy of INM004 in Children With STEC-HUS

Start date: May 16, 2024
Phase: Phase 3
Study type: Interventional

The objectives of this study are to evaluate the efficacy, safety, and pharmacokinetics of INM004 in pediatric patients with Hemolytic Uremic Syndrome associated to infection by Shiga toxin-producing Escherichia coli (STEC-HUS).

NCT ID: NCT06349577 Not yet recruiting - Surgery Clinical Trials

Optimizing Pulsatility During Cardiopulmonary Bypass to Reduce Acute Kidney Injury

Start date: April 2024
Phase: N/A
Study type: Interventional

The objective is to determine the effectiveness of pulsatile flow during cardiopulmonary bypass to reduce the incidence of acute kidney injury after cardiac surgery. Investigators will also evaluate the safety and impact of pulsatile flow on clinical outcomes compared to non-pulsatile flow during cardiopulmonary bypass.

NCT ID: NCT06341582 Recruiting - Neonatal Jaundice Clinical Trials

Prediction and Evaluation by ETCOc of Neonatal Hyperbilirubinemia Cohort

PREVENT
Start date: December 11, 2023
Phase:
Study type: Observational [Patient Registry]

The hemolytic disease of newborns (HDN) is one of the most significant risk factors for hyperbilirubinemia. Studies have shown that end-tidal carbon monoxide-corrected (ETCOc) correlated with the rate of bilirubin production in the body and thus can be a good surrogate to quantify hemolysis and identifying the high-risk infants. However, there is insufficient clinical evidence regarding the early prediction of hemolytic hyperbilirubinemia using ETCOc. This study hypothesizes that early postnatal ETCOc levels are significantly associated with the risk of hemolytic hyperbilirubinemia requiring treatments within 14 days after birth, and early postnatal ETCOc can be a good indicator for early prediction of hemolysis. In addition, the investigators aim to investigate the relationship between the characteristics of treatments for hyperbilirubinemia and ETCOc.

NCT ID: NCT06270134 Not yet recruiting - Renal Failure Clinical Trials

Dial-Bicarb Trial: Effects of a Lower vs. Higher Concentration of Dialysate Bicarbonate

Start date: January 2025
Phase: N/A
Study type: Interventional

This is a pragmatic, two-arm, parallel-group, open-label, individual-randomized, superiority trial that will be conducted in hemodialysis units across Ontario. Patients at each dialysis unit will be randomly allocated into one of two study arms in a 1:1 ratio to receive a dialysate bicarbonate concentration of either 32 or 38 mmol/L. The intervention will be embedded into routine care and delivered by hemodialysis unit personnel.

NCT ID: NCT06231368 Recruiting - Clinical trials for Autoimmune Hemolytic Anemia

CNCT19 for Patients With Autoimmune Hemolytic Anemia After Failure ≥3 Lines of Therapy.

Start date: February 4, 2024
Phase: Phase 1
Study type: Interventional

This is a Phase 1, single-arm, open-label, dose-escalation and dose-expansion study. The main purpose is to evaluate the safety and tolerability, efficacy of CNCT19 CAR T-cell therapy in patients with autoimmune hemolytic anemia after failure of three or more lines of therapy. Participants will receive CNCT19 cell infusion after preconditioning, and they will receive a 1-year follow-up.

NCT ID: NCT06223802 Recruiting - Hemolysis Clinical Trials

Biodex Training in Hemodialysis Females With Osteopenia

Start date: November 8, 2023
Phase: N/A
Study type: Interventional

imbalance is a common problem in hemodialysis patients with osteopneia, biodex training is a good device that treat imbalance

NCT ID: NCT06215339 Completed - Healthy Clinical Trials

Diet Therapy in Hemodialysis Patients

Start date: May 1, 2023
Phase: N/A
Study type: Interventional

This study determined the effect of dietary education given to hemodialysis patients on dietary treatment and symptoms.

NCT ID: NCT06212154 Recruiting - Clinical trials for Autoimmune Hemolytic Anemia

CAR-T for Autoimmune Hemolytic Anemia Patients Who Have Failed Three or More Lines of Therapy

Start date: January 20, 2024
Phase: Phase 1
Study type: Interventional

To Evaluate the Safety and Efficacy of ThisCART19A for Relapsed/Refractory Autoimmune Hemolytic Anemia Patients After Receiving Three or More Lines of Therapy

NCT ID: NCT06198933 Not yet recruiting - Atrial Fibrillation Clinical Trials

Renal Function and Hemolysis After Pulsed-field Ablation for Atrial Fibrillation

Start date: February 1, 2024
Phase:
Study type: Observational

The aim of the project is to assess hemolysis and renal function after catheter ablation for atrial fibrillation using pulsed-field energy. Hemolysis will be determined using the concentration of red blood cell microparticles at the end of the ablation (when all ablation were done, before sheath removal). Hemoglobinuria will be assessed one day after the procedure. Renal functions will be assessed one and three day after the procedure using standard parameters (creatinine, urea). The goal is to assses the acute worsening fo renal functions after pulsed-field ablation in relation to the number of PF applications, and to the degree of immediate post-procedural hemolysis.