The Impact of High-Fat Ketogenic Diet and Low-Fat Diet in Women Body Weight

Healthy Clinical Trial

Official title:

The Impact of High-Fat Ketogenic Diet and Low-Fat Diet in the Body Weight and Cardiovascular Risk Factors on Overweight and Obese Saudi Women: A Randomized Controlled Trial.

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05811702
• Other study ID #: KingFaisalU
• Status: Recruiting
• Phase: N/A
• Start date: July 1, 2023
• Est. completion date: November 1, 2023

Study information

• Verified date: June 2023
• Source: King Faisal University
• Contact: Randah Alqurashi, PhD
• Phone: 00966559223608
• Email: ralqurashi[@]kfu.edu.sa
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The aim of this study is investigated the effect of high fat Ketogenic Diet (HFKD) in weight reduction compared to the low-fat diet (LFD) among Saudi overweight and obese women. A randomized acute controlled trial of twenty-eight healthy overweight or obese women in Saudi Arabia, aged between 18 and 40 with a body mass index between 25 and 34.5 kg m2 and fat parentage above 30% . The participants have followed ether HFKD or LFD for 12 weeks.

Description:

Obesity is associated with an increased risk of high blood pressure and heart muscle damage, which leads to cases that increase the chances of developing cardiovascular diseases, and if weight gain is not controlled, these results lead to obesity is the main cause of cardiovascular disease and causes dyslipidemia, high blood pressure and diabetes. Recently, there have been followed systems and programs food some of which are beneficial for health and some of them are unhealthy systems. The diet is one of the most controversial issues. The aim of this study is investigated the effect of high fat Ketogenic Diet (HFKD) in weight reduction compared to the low-fat diet (LFD) among Saudi overweight and obese women. A randomized acute controlled trial of twenty-eight healthy overweight or obese women in Saudi Arabia, aged between 18 and 40 with a body mass index between 25 and 34.5 kg m2 and fat parentage above 30% . The participants have followed ether HFKD or LFD for 12 weeks. Our primary outcome of this study to investigated the effective diets HFKD and LFD on reduction of body weight, the percentage of body fat, The secondary outcomes have evaluated at the percentage of body fat, blood glucose, lipid profile.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 28
• Est. completion date: November 1, 2023
• Est. primary completion date: October 1, 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 18 Years to 40 Years

Eligibility

Inclusion Criteria:

• Healthy Overwight and obese wonen

• aged 18 and 40

• BMI 25 and 34.5 kg m2

• fat parentage above 30% .

Exclusion Criteria:

• Man

• women in normal weight or BMI less than 25 and 34.5 kg m2

• Breastfeeding and pregnant women

Related Conditions & MeSH terms

• Body Weight
• Healthy
• Overweight
• Overweight and Obesity

Intervention

Other:
• A randomized acute controlled trial of twenty-eight healthy overweight or obese women
A randomized acute controlled trial of twenty-eight healthy overweight or obese women in Saudi Arabia, aged between 18 and 40 with a body mass index between 25 and 34.5 kg m2 and fat parentage above 30% . The participants have followed ether HFKD or LFD for 12 weeks. Our primary outcome of this study to investigated the effective diets HFKD and LFD on reduction of body weight, the percentage of body fat

Locations

Country	Name	City	State
Saudi Arabia	Randah Alqurashi	Riyadh

Sponsors (1)

Lead Sponsor	Collaborator
King Faisal University

Country where clinical trial is conducted

Saudi Arabia, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Body weight (kg) and BMI	primary outcome of this study to investigated the effective diets HFKD and LFD on reduction of body weight, the percentage of body fat,	12 weeks
Primary	percentage of body fat	Primary outcome of this study to investigated the effective diets HFKD and LFD on reduction of percentage of body fat,	12 weeks
Secondary	Total Cholesterol mg/dl	Secondary outcome of this study to investigated the effective diets HFKD and LFD on total Cholesterol mg/dl	12 weeks
Secondary	Triglycerides) mg/dl (	Secondary outcome of this study to investigated the effective diets HFKD and LFD on total Triglycerides) mg/dl (	12 weeks
Secondary	HDL) mg/dl (	HDL) mg/dl (	12 weeks
Secondary	LDL) mg/dl (	LDL) mg/dl (	12 weeks
Secondary	Glucose (mg/dl)	Glucose (mg/dl)	12 weeks
Secondary	Hb Aic (%)	Hb Aic (%)	12 weeks