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Gingivitis clinical trials

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NCT ID: NCT06212908 Completed - Breast Cancer Clinical Trials

Assessment of Periodontal Therapy and Biofilm Management in Breast Cancer

BREASTCANCER
Start date: September 18, 2012
Phase: N/A
Study type: Interventional

Objective: To evaluate the impact of chemotherapy on periodontal conditions, hematology, and salivary flow in patients with breast cancer and gingivitis, after basic periodontal therapy (BPT). Methods: They were divided into patients with breast cancer and gingivitis (BC/G =20); and patients without cancer with gingivitis (G=20). Clinical parameters [Plaque Index (PI), bleeding on probing (BOP), Probing Depth (PS), Clinical Attachment Level (CAL)], hematological parameters (complete blood count), and salivary flow were evaluated at baseline, 6, 12 and 24 weeks.

NCT ID: NCT06144034 Completed - Epilepsy Clinical Trials

Air Polishing Effect on Biological, Clinical and Patient-reported Experience Among Epileptic and Non-epileptic Children

Start date: March 1, 2022
Phase: N/A
Study type: Interventional

In epileptic and non Epileptic children, the full dentition of each patient was split into four quadrants, starting from the upper right quadrant (1) and moving clockwise until the lower right quadrant (4). Bundled into two groups: quadrant (1+3) vs. (2+4). After randomization, each of these pairs of quadrants had the same treatment modality; test quadrants received treatment with airflow to remove soft biofilm, and ultrasonic scaler for areas with calculus deposits, and control quadrants were treated with conventional rubber cup polishing to remove soft biofilm and ultrasonic scaler for calculus deposits.

NCT ID: NCT06143670 Completed - Gingivitis Clinical Trials

A Clinical Study Investigating the Effects of a Dentifrice Containing 0.454% Stannous Fluoride on Gingivitis Treatment and Plaque Reduction When Used Twice Daily for 12 Weeks

Start date: November 29, 2023
Phase: N/A
Study type: Interventional

The purpose of this clinical study is to investigate the efficacy of a dentifrice containing 0.454 percent (%) weight by weight (w/w) stannous fluoride (SnF2), on gingivitis treatment and plaque reduction, compared to a regular fluoride dentifrice after 12 weeks twice daily brushing in a population of clinically diagnosed gingivitis without undergoing dental prophylaxis.

NCT ID: NCT06140784 Completed - Gingivitis Clinical Trials

A Clinical Study to Assess the Gingivitis and Plaque Effects of Various Dentifrices

Start date: September 2, 2023
Phase: N/A
Study type: Interventional

The primary objective of this study is to evaluate the effect four different dentifrices have on gingivitis after 12 weeks of product use. The secondary objectives are to assess the effect four dentifrices, have on plaque and oral microbiome composition.

NCT ID: NCT06140771 Completed - Gingivitis Clinical Trials

A Clinical Study to Assess the Gingivitis Effects of Various Dentifrices

Start date: October 20, 2021
Phase: N/A
Study type: Interventional

The objective of this learning clinical study is to assess the gingivitis effects of four different dentifrices over a 3-month period.

NCT ID: NCT06135116 Completed - Periodontitis Clinical Trials

Regulatory T Cell With Related Interleukins in Periodontal Disease Progression

Start date: November 1, 2023
Phase:
Study type: Observational

T Regulatory cells which suppressor subset of T cells and related cytokines remain in blood and infiltrates into the tissue under need. The role of Treg and related cytokines in succession of periodontal inflammation is recently a subject of research interest. Chronic gingivitis and periodontitis being chronic inflammatory diseases can upregulate various cytokines in the systemic circulation and gingival crevicular fluid. This study aimed to compare levels of Tregs with Interleukin-21, 22, 33, 35 and vitamin D-binding protein in blood and GCF of periodontally healthy persons, chronic gingivitis patients, and severe chronic periodontitis patients.

NCT ID: NCT06128850 Completed - Periodontitis Clinical Trials

Peri-implant Conditions Mimic Periodontal Conditions

Start date: July 4, 2022
Phase:
Study type: Observational

Except for patients with referred clinical bruxism and uncontrolled medical conditions, the study included 123 implants with implanted fixed prostheses that had lasted at least six months after functional prosthetic loading. In all implant patients, the health scale ranged from implants and natural teeth to plaque, gingival index, bleeding in the probe, mouth depth, loss of clinical attachment, and dental implants. The health and illness of the implants have been determined. Patients were divided into three groups: peri-implantitis, peri-implant mucositis, and peri-implant health. Inclusion Criteria: - Patients between the ages of 18- 70 - Drugs that have a systemically healthy and controlled treatment situation - Drivers who have implant-supported fixed prostheses that have been at least six months after functional prosthetic loading Among these groups, it was checked whether periodontitis was seen in patients with peri-implantitis, gingivitis in patients with peri-implant mucositis, and whether healthy gums were seen in individuals with peri-implant health. To determine the health and disease status of individuals' implants, plaque index (Silness Loe 1964), gingival index (Loe Silness 1963), bleeding on probing (Ainoma Bay 1975), pocket depth measurements, and clinical attachment level were collected.

NCT ID: NCT06126250 Completed - Clinical trials for Plaque Induced Gingivitis

Safety and Efficacy of U-Shaped Sonic Toothbrush on Plaque and Gingivitis

Start date: September 11, 2023
Phase: N/A
Study type: Interventional

The goal of this 30 day, randomized, two group, parallel, examiner-blind clinical study is to evaluate the safety and efficacy of AutoBrush® 360° U-shaped Sonic Toothbrush on supragingival dental plaque and gingivitis, compared to an American Dental Association (ADA) reference manual soft toothbrush. The extent of gingival abrasion and recession and oral safety will be evaluated.

NCT ID: NCT06122376 Completed - Clinical trials for Plaque Induced Gingivitis

Plaque and Gingivitis Evaluation of a U-Shaped Toothbrush in a 30-Day Model

Start date: May 31, 2023
Phase: N/A
Study type: Interventional

The objective of this 30 day, randomized, two group, parallel, examiner-blind clinical trial is to assess the safety and efficacy of AutoBrush® 360° U-shaped Sonic Toothbrush on plaque and gingivitis, compared to an American Dental Association (ADA) reference manual soft toothbrush. The extent of gingival abrasion and recession and oral safety will be evaluated.

NCT ID: NCT06110221 Completed - Periodontitis Clinical Trials

Activin-A and Interleukin-1β Levels in Periodontitis

Start date: March 22, 2019
Phase:
Study type: Observational [Patient Registry]

Activin-A belongs to the transforming growth factor-beta superfamily and is a multifunctional cytokine that plays a role in inflammation, immune response, tissue repair and regeneration. Proinflammatory cytokine interleukin-1beta (IL-1β) can increase Activin-A expression in various cell types. This study aims to evaluate gingival crevicular fluid (GCF) and salivary Activin-A and IL-β levels in stage III periodontitis. Seventy-five systemically healthy and non-smoker volunteers consisting of 23 stage III periodontitis, 26 gingivitis and 26 periodontally healthy were enrolled. Full-mouth clinical periodontal indices were recorded, unstimulated whole saliva and GCF samples were obtained, Activin-A and IL-1β total amounts were determined by enzyme-linked immunosorbent assay. Statistical comparisons were performed using non-parametric tests.