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Hepcidin and Glucose Metabolism

Gestational Diabetes Clinical Trial

Official title:
The Effect of Oral Iron Supplements on Hepcidin, Insulin and Glucose Metabolism in Pregnancy

Clinical Trial Summary

Gestational diabetes mellitus (GDM), defined as hyperglycemia with blood glucose values above normal but below those diagnostic of DM, and iron deficiency (ID) with or without anemia (IDA) are common during pregnancy. Both disease patterns are associated with an increased risk of complications during pregnancy and at delivery and may have a variety of negative effects on different aspects of child development. Thus, GDM and ID/IDA during pregnancy should be prevented. Whether iron supplementation with high oral doses acutely increases hepcidin during pregnancy, and whether this acute iron-induced increase in hepcidin decreases insulin sensitivity, is uncertain.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04008147
Study type Interventional
Source Swiss Federal Institute of Technology
Contact Nicole U Stoffel, PhD
Phone +41 44 632 83 93
Email nicole.stoffel@hest.ethz.ch
Status Recruiting
Phase N/A
Start date July 3, 2019
Completion date December 31, 2023
View Details
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