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Glucose Intolerance clinical trials

View clinical trials related to Glucose Intolerance.

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NCT ID: NCT03459573 Recruiting - Clinical trials for Diabetes Mellitus, Type 2

Fit-One: A Trial Evaluating the Effect of One Drop and Fitbit on Diabetes and Pre-diabetes Outcomes

Start date: February 16, 2018
Phase: N/A
Study type: Interventional

The Fit-One trial involves three prospective, randomized waitlist-controlled studies. These studies evaluate the effects of One Drop's digital therapeutics solution with and without Fitbit devices on the social cognitive, behavioral, and health outcomes of people with diabetes. Fit-One is being tested on adults with type 1 diabetes (T1D) of all weights, and adults with type 2 diabetes (T2D) or pre-diabetes that are overweight or obese (BMI ≥ 25).

NCT ID: NCT03426228 Not yet recruiting - Obesity Clinical Trials

In Vitro Fertilization Impact on Metabolic Parameters

Start date: February 10, 2018
Phase: N/A
Study type: Observational [Patient Registry]

A quantitative prospective cohort study will be conducted, where blood samples will be collected at different timings during the IVF protocol, to assess the impact of fertility medications on metabolic parameters of patients undergoing IVF treatment.

NCT ID: NCT03419702 Recruiting - Clinical trials for Overweight and Obesity

Almonds and Health Effects on Metabolism, Vascular Function and Cognition

Start date: January 10, 2018
Phase: N/A
Study type: Interventional

The primary objective of the proposed study is to examine and understand the impact of long-term almond consumption on chronic glucose metabolism in subjects with impaired glucose tolerance.

NCT ID: NCT03403231 Recruiting - Prediabetes Clinical Trials

INcreasing Veteran EngagemeNT to Prevent Diabetes (INVENT)

Start date: February 1, 2018
Phase: N/A
Study type: Interventional

This study will evaluate a VA MyHealtheVet Secure Messaging intervention that uses different intervention messaging strategies designed to increase engagement in behaviors to prevent type 2 diabetes. The investigators will enroll 144 eligible Veterans into a 12-week MyHealtheVet Secure Messaging intervention. Eligible Veterans include those who are currently using MyHealtheVet secure messaging, meet inclusion/exclusion criteria, and have received an HbA1c test within the last 6 months that meets the ADA/CDC classification for prediabetes. Study participants will be surveyed about their engagement in behaviors to prevent TDM2 and mediators of this engagement. After completing a baseline survey, participants will be randomly assigned to receive different novel presentations of information about ways to prevent T2DM through both Secure Messaging and US Mail. The investigators will test the 5 presentations that each: (1) represent an innovative approach from behavioral economics or health psychology with great promise to increase engagement in behaviors to prevent T2DM among patients with prediabetes; and (2) have not been tested in this setting.

NCT ID: NCT03398902 Not yet recruiting - PreDiabetes Clinical Trials

Personalizing Sleep Interventions to Prevent Type 2 Diabetes in Community Dwelling Adults With Pre-Diabetes

Start date: March 3, 2020
Phase: N/A
Study type: Interventional

This study will use continuous glucose monitoring and actigraphy to examine whether a personalized, daily sleep extension intervention improves glucose regulation for community dwelling, sleep-restricted adults with pre-diabetes. The randomized controlled trial will include 150 adults with pre-diabetes. Sleep extension and habitual sleep groups will complete daily sleep diaries and participate in a weekly 15-minute telephone call or videoconference meeting with a member of the study team (8 sessions total). Data collection will be at 2 time points: pre-randomization and post-intervention (completion of the 8-week intervention). Changes in the percent time glucose is ≥ 140mg/dL at baseline and post-intervention will be established and compared across the sleep extension and habitual sleep arms.

NCT ID: NCT03398356 Recruiting - PreDiabetes Clinical Trials

Metformin and Its Impact on the Substances Associated With NO Production in Prediabetes Patients.

Start date: October 20, 2017
Phase: Phase 4
Study type: Interventional

This study evaluates the effect of different doses of metformin on the function of endothelium in people with pre-diabetes. One group of the patients will receive metformin in dose: 1500 mg, the second one will receive 3000 mg/day.

NCT ID: NCT03389100 Enrolling by invitation - Clinical trials for Diabetes Mellitus, Type 2

Tau PET Imaging in the Northern Manhattan Study of Metabolism and Mind.

Start date: March 5, 2018
Phase: Phase 2
Study type: Interventional

This is a single center brain Positron Emission Tomography (PET) study of 18F-MK-6240. Eligible participants are persons from Northern Manhattan who self-identify as Hispanic, non-Hispanic Black, or Non-Hispanic White, who are 55 to 69 years of age, of both sexes, without dementia, who have already agreed to undergo, of have undergone, brain amyloid PET and magnetic resonance imaging (MRI). Those eligible will have one brain PET scan with 18F-MK-6240, repeated after 18 months to 30 months. Vital signs will be checked prior to injection of 18F-MK-6240 and again at the completion of the PET scan. The primary objective is to relate diabetes status and glycemia to in-vivo brain tau accumulation, across and within ethnic and racial groups.

NCT ID: NCT03383068 Not yet recruiting - Clinical trials for Impaired Glucose Tolerance

Research of Intensive Metabolic Intervention Before Pregnancy in PCOS

Start date: January 1, 2018
Phase: Phase 4
Study type: Interventional

To investigate whether intensive metabolic intervention of PCOS women before pregnancy can improve pregnancy outcome.Besides, the investigators aim to investigate the best therapy strategy of metabolic intervention before pregnancy.The investigators plan to recruit PCOS women at childbearing age. By using acarbose, GLP-1 analogue, berberin et al. the investigators will intervent the participants' metabolic statues for 3 months before pregnancy and to compare outcome in each group.

NCT ID: NCT03377946 Recruiting - Clinical trials for Type 2 Diabetes Mellitus

Effect of Probiotics on Pre-diabetes and Diabetes in China

Start date: December 21, 2017
Phase: N/A
Study type: Interventional

This study is aimed at verifying the effects of probiotics (KAWAI:dead S.thermophilus) on glucos management among T2DM and pre-diabetes Chinese adult. Additionally, the investigators intend to verify the effects of probiotics on modifying the structure and function of gut microbiome.

NCT ID: NCT03376685 Not yet recruiting - Obesity Clinical Trials

The Relationship Between Exercise Frequency, Intensity, and Restoration of Cardiometabolic Health

Start date: January 2018
Phase: N/A
Study type: Interventional

Regular physical activity is well established to decrease the risk of cardiometabolic diseases, however these beneficial effects are largely dependent on the type of exercise protocol conducted. The purpose of this study is to directly compare the efficacy of endurance (END), sprint (SIT), or combined endurance-sprint (COMB) training in respect to reducing clinically relevant cardiometabolic risk factors in pre-diabetic individuals. It is hypothesized that: 1. END and COMB will elicit favourable cardiovascular adaptations, which will be absent in response to SIT. 2. END and COMB protocols of greater frequency will markedly improve metabolic health in comparison to a lower frequency SIT protocol.