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Diabetes Mellitus, Type 2 clinical trials

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NCT ID: NCT01435616 Completed - Clinical trials for Diabetes Mellitus, Type 2

A Study in Patients With Type 2 Diabetes Mellitus

IMAGINE 2
Start date: November 2011
Phase: Phase 3
Study type: Interventional

The purpose of this study is: - To compare blood sugar control on LY2605541 with insulin glargine after 52 weeks of treatment. - To compare the rate of night time low blood sugar episodes on LY2605541 with insulin glargine during 52 weeks of treatment. - To compare the number of participants on LY2605541 reaching blood sugar targets without low blood sugar episodes at night to those taking insulin glargine after 52 weeks of treatment. - To compare the rate of low blood sugar episodes on LY2605541 with insulin glargine after 52 weeks of treatment

NCT ID: NCT01435603 Completed - Obesity Clinical Trials

Intervening in Diabetes With Healthy Eating, Activity, and Linkages To Healthcare - The I-D-HEALTH Study

I-D-HEALTH
Start date: August 2011
Phase: N/A
Study type: Interventional

The purpose of this study is to compare ways of giving advice and providing support to improve diet and physical activity in adult primary care patients with elevated body mass index and dysglycemia.

NCT ID: NCT01434186 Completed - Clinical trials for Diabetes Mellitus, Type 2

A Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Saxagliptin (BMS-477118) in Combination With Metformin IR or Metformin XR in Pediatric Patients With Type 2 Diabetes Who Have Inadequate Glycemic Control on Metformin Alone

Start date: May 2012
Phase: Phase 3
Study type: Interventional

To evaluate the efficacy, safety, tolerability, of Saxagliptin (BMS-477118) in combination with Metformin in pediatric patients with type 2 diabetes

NCT ID: NCT01434030 Completed - Clinical trials for Diabetes Mellitus, Type 1

Development of a Behavioral Observer for Type 1 Diabetes Mellitus

Phase1
Start date: April 2010
Phase: N/A
Study type: Interventional

Development of a bio-behavioral stochastic model-predictive controller (SMPC) for use as an artificial pancreas in T1DM requires fundamental behavioral and physiology studies, as well as translational modeling and engineering development. In order to be successful, closed-loop control in Type 1 Diabetes Mellitus (T1DM) must adapt to individual physiologic characteristics and to the behavioral profile of each person. An essential part of this adaptation is biosystem (patient) observation. The investigators propose to lay the foundation for a closed-loop control system which will include algorithmic observers of patients' behavior and metabolic state.

NCT ID: NCT01433419 Completed - Diabetes Mellitus Clinical Trials

Open-label Study of TAK-875

Start date: January 2012
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of treatment with TAK-875 in diabetic patients.

NCT ID: NCT01433406 Completed - Diabetes Mellitus Clinical Trials

Long-term Study of TAK-875

Start date: October 2011
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of long-term treatment with TAK-875 in diabetic patients.

NCT ID: NCT01433393 Completed - Diabetes Mellitus Clinical Trials

Double-blind Comparative Study of TAK-875

Start date: n/a
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of treatment with TAK-875 in diabetic patients.

NCT ID: NCT01433380 Completed - Clinical trials for Diabetes Mellitus, Type 2

A Study To Evaluate PF-05175157 In Healthy Volunteers

Start date: July 2011
Phase: Phase 1
Study type: Interventional

The primary purpose of this study is to evaluate the pharmacodynamics of single oral doses of PF-05175157 in healthy volunteers

NCT ID: NCT01432938 Completed - Clinical trials for Diabetes Mellitus, Type 2

A Study of the Effect of Dulaglutide on the Action of Warfarin in Healthy Participants

Start date: September 2011
Phase: Phase 1
Study type: Interventional

Warfarin is a commonly used drug to prevent the blood from clotting. The purpose of this study is to determine if dulaglutide (LY2189265) affects how warfarin works. The study involves two different treatments (Treatment 1: warfarin; Treatment 2: dulaglutide + warfarin) separated by a minimum washout period of 24 days. In Treatment 1, the participant will receive 10 milligrams (mg) of warfarin on Day 1. In Treatment 2, the participant will receive a 1.5-mg dose of dulaglutide (LY2189265) as an injection on Day 1 and then a 10 mg dose of warfarin on Day 3. Participants will be randomly assigned into different treatment sequences. Participants in Treatment Sequence A will receive Treatment 1 then Treatment 2. Participants in Treatment Sequence B will receive Treatment 2 then Treatment 1.

NCT ID: NCT01432275 Completed - Diabetes Mellitus Clinical Trials

Ease of Use of New Blood Glucose Meter With In-built Insulin Calculator at Home Study

IHUT
Start date: September 2011
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate user preference and ease of use of the FreeStyle InsuLinx system, compared to current methodology, when used at home by subjects with diabetes. Subjects will also be comparing the ease of use of the FreeStyle InsuLinx system with comparator meters.