Clinical Trials Logo

Diabetes Mellitus, Type 2 clinical trials

View clinical trials related to Diabetes Mellitus, Type 2.

Filter by:

NCT ID: NCT02651480 Suspended - Clinical trials for Diabetes Mellitus, Type 2

A Nutritional Intervention in Police Officers

Start date: February 2016
Phase: N/A
Study type: Interventional

The proposed study seeks to test the effect of a plant-based dietary intervention on cardiovascular risk factors in police officers.

NCT ID: NCT02594748 Suspended - Clinical trials for Diabetes Mellitus, Type 2

The Effects of Self-management Education Based on Theory of Planned Behavior on Patients With Type 2 Diabetes

Start date: July 2015
Phase: N/A
Study type: Interventional

The aims of the study are as follows: - To improve self-management intention and behavior of patients with type 2 diabetes (T2 DM). - To promote patients to make plans for their self-management and gradually integrate the self-management plan into their daily life. - To improve resilience, well-being, fatigue and quality of life of patients with T2 DM In order to achieve the aims, we have set the following objectives: - To develop and apply self-management education program based on the extended theory of planned behavior. - To evaluate the efficacy of the educational program: 1. Self-management education program delivered face to face (intervention group); (b) standard usual care (comparison group).

NCT ID: NCT01931631 Suspended - Clinical trials for Diabetes Mellitus, Type 2

Plant-Based Dietary Intervention in Type 2 Diabetes-2

WCCR-DIAB2
Start date: January 2014
Phase: N/A
Study type: Interventional

The purpose of the study is to assess whether, in individuals with type 2 diabetes, a low-fat, vegan diet improves blood glucose control more effectively than a control diet based on current American Diabetes Association (ADA) guidelines. The principal measure is hemoglobin A1c. Cardiovascular risk factors and dietary acceptability are also assessed. The study duration is 20 weeks with a one-year follow-up.

NCT ID: NCT01878045 Suspended - Clinical trials for Diabetes Mellitus, Type 2

Mechanisms of Diabetic Kidney Disease in American Indians

Start date: November 7, 2013
Phase:
Study type: Observational

Background: - An ongoing study is looking at American Indians who have kidney problems caused by type 2 diabetes. Kidney disease due to type 2 diabetes is a major problem in American Indians. We previously found that early treatment of kidney disease with losartan was probably beneficial for reducing progression of the disease. Researchers now want to see if these benefits continue to be seen several years after the end of the treatment study. Objectives: - To study long-term benefit of losartan treatment for diabetic kidney disease in American Indians with type 2 diabetes. Eligibility: - Participants in the American Indian diabetic kidney disease study (OH95-DK-N037). Design: - Participants will have a physical exam and medical history before starting the study. Blood and urine samples will be collected. - Participants will have a set of tests as part of this study. Those who have severe kidney problems, such as kidney failure, will only have a basic kidney exam with scans. The remaining participants will have a full urine collection and analysis. They will also provide a kidney biopsy. - Treatment will not be provided as part of this study.

NCT ID: NCT01472809 Suspended - Diabetes Clinical Trials

A Clinical Study to Evaluate Safety, Tolerability and Pharmacokinetics of Oral ZYGK1 in Healthy Volunteers

Start date: December 2011
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine (1) whether ZYGK1 is safe and well tolerated, (2) the pharmacokinetics (what body does to ZYGK1) and (3) pharmacodynamics (what drugs does to the body) in the healthy and diabetic subject.

NCT ID: NCT01213277 Suspended - Diabetes Mellitus Clinical Trials

A1c Discordance in Diabetes Patients

Start date: October 2010
Phase: N/A
Study type: Interventional

HbA1c is used as a gold standard to see whether patients have optimal glycemic control. Today, many physicians rely solely on HbA1c to change medication. However, there is a select group of patients that have low average glucose levels but high HbA1c levels. The investigators believe that these patients are fast glycators meaning that they incorporate sugar into their hemoglobin faster than normal. The investigators want to determine whether these patients are fast glycators.

NCT ID: NCT01114750 Suspended - Diabetes Mellitus Clinical Trials

A Study to Determine the Absorption of Peroral Insulin in Dextran Matrix (ORA3)

ORA3
Start date: April 2010
Phase: Phase 1
Study type: Interventional

A pharmacokinetic study on the absorption of perorally delivered insulin in dextran matrix after single dose administration.

NCT ID: NCT01114061 Suspended - Diabetes Clinical Trials

Evaluation of the Effects of Heating the Vicinity of the Insulin Delivery Site by the InsuPatch Device During Daily Life

Start date: n/a
Phase: N/A
Study type: Interventional

The aim of this study is to test the performance of the InsuPatch device in daily life. The primary target of the study is to evaluate safety aspect of daily device use. Additional aspects to be evaluated in the study are: the effect of the device on post prandial glucose level.

NCT ID: NCT00990444 Suspended - Diabetes Mellitus Clinical Trials

A Two Part Study of Peroral Insulin in Type 2 Diabetes

ORA2
Start date: September 2009
Phase: Phase 1/Phase 2
Study type: Interventional

Insulin is normally not bioavailable when taken through the oral route, as degradation of the molecule may occur both in the ventricle and in the intestine. Oral administration with uptake from the lesser intestine would offer major advantages if made possible. It would offer a simple non-injection method to administer insulin in connection with a meal and absorbed insulin would enter the blood stream and mimic the natural distribution in the body with a first pass through the liver. The sponsor of this study has developed a novel oral insulin formulation that is based on a proprietary dextran matrix. The investigational drug is a capsule containing 100 IU of human insulin in dextran matrix. The primary objective of this study is to establish the safety, tolerance and PD profile (i.e. pharmacodynamic parameters for glucose and insulin) of peroral insulin in dextran matrix in patients with type 2 diabetes. The phase I/II study protocol consists of two parts; part 1 (dose finding) and part 2 (dose verification). In study part 1 single escalating doses of oral insulin or placebo is given to the test subjects. Capillary blood glucose is used to assess the insulin effect. Subsequently, in study part 2, the investigational drug will be administered 3 times daily on 6 consecutive days. The starting dose of part 2 will be the lowest effective dose found in study part 1. Dose escalation will be done in increments of 100 IU. The total number of subjects will be 32 (for part 1 and 2 combined).

NCT ID: NCT00793884 Suspended - Diabetes Clinical Trials

Emory Latino Diabetes Education Program

ELDEP
Start date: October 2008
Phase:
Study type: Observational

Latinos with diabetes who are attending the Emory Latino Diabetes education program will be approached about consenting to have clinical measurements collected to assess changes between baseline and monthly follow up sessions. The no-cost educational sessions follow the self-care behavior curriculum of the American Association of Diabetes Educators (AADE).