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Diabetes Mellitus, Type 2 clinical trials

View clinical trials related to Diabetes Mellitus, Type 2.

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NCT ID: NCT06051058 Not yet recruiting - Heart Failure Clinical Trials

Care Transitions App for Patients With Multiple Chronic Conditions

Start date: August 2024
Phase: N/A
Study type: Interventional

The objective of this study is to widely implement and evaluate the Care Transitions App in a randomized controlled trial. The app the investigators designed for patients with multiple chronic conditions has four envisioned modules: 1) falls-reduction content, 2) a digital post-discharge transitional care plan (e.g., after hospital care plan, including education, medications, follow-up appointments, warning signs to watch for, nutrition, and other care plan activities), 3) a new module for patients with MCC (diabetes, congestive heart failure, and chronic kidney disease) including condition-specific post-discharge care plans with relevant symptom management activities, 4) a new post-discharge report module which summarizes key care transition findings and allows for patients to enter notes and questions for their providers and their own goals for recovery.

NCT ID: NCT06047262 Not yet recruiting - Clinical trials for Diabetes Mellitus, Type 2

Dapansutrile in Diabetes and Diabetes-Related Complications - Dapan-Dia

Dapan-Dia
Start date: May 2024
Phase: Phase 2
Study type: Interventional

The aim of the study is to determine whether NLRP3 inhibition with dapansutrile represents a new pharmacological option for diabetes management with potential as an anti-inflammatory agent to also address micro- and macro-vascular risk and complications from diabetes.

NCT ID: NCT06040164 Not yet recruiting - Obesity Clinical Trials

Oral Endocannabinoids in People With Prediabetes and Diabetes

SMILE
Start date: October 1, 2023
Phase:
Study type: Observational

This study evaluates the relationship of endocannabinoids in saliva with inflammation and oral dysbacteriosis present in people with periodontal disease and prediabetes/type 2 diabetes

NCT ID: NCT06037551 Not yet recruiting - Diabetes Clinical Trials

System Accuracy of the Blood Glucose Monitor for Personal Use Contour Care

Start date: October 1, 2023
Phase: N/A
Study type: Interventional

This study assesses the system accuracy of a blood glucose monitoring system in accordance with DIN EN ISO 15197:2015

NCT ID: NCT06035406 Not yet recruiting - Diabetes Clinical Trials

A Trial of SP2086 With Hepatic Insufficiency

Start date: September 2023
Phase: Phase 1
Study type: Interventional

This study used a single-dose, open design to compare the pharmacokinetics of subjects with mild and moderate liver impairment and subjects with normal liver function.

NCT ID: NCT06005051 Not yet recruiting - Clinical trials for Diabetes Mellitus, Type 2

Prediabetes Stratification by Multi-omics Profile After Food Intake

Start date: May 1, 2024
Phase: N/A
Study type: Interventional

1 in 3 adults have prediabetes in the United States, and many of them will eventually develop diabetes, which has significant public health and economic costs. However, type 2 diabetes (T2D) and prediabetes are heterogeneous groups with different pathological mechanisms, dysfunctions in different processes, and varied disease trajectories. Patient stratifications into subtypes and personalized nutrition interventions are highly needed but not yet available. Metabolic responses (e.g., glucose excursion) after food intake provide a direct observation of personal metabolic control and its association with T2D. The investigators hope to learn how prediabetes and type 2 diabetes evolve, and specifically what food or exercise can do to mitigate blood sugar response.

NCT ID: NCT05994755 Not yet recruiting - Heart Failure Clinical Trials

Association Between Cardiac ARRHYTHMIAs and Glycemic Variability in Patient With Type 2 Diabetes Monitored Through FREEstyle Libre and Bluetooth Technology.

ARRHYTHMIAFREE
Start date: October 30, 2023
Phase:
Study type: Observational [Patient Registry]

The aim of this study is to investigate the association between hypoglycemia, glycemic variability and cardiac arrhythmias in patients with diabetes Type II (T2D) already implanted with implantable cardiac defibrillator (ICD) and monitored remotely through Bluetooth technology and CGM (continuous glucose monitoring).

NCT ID: NCT05990933 Not yet recruiting - Hypoglycemia Clinical Trials

Role of Adrenaline in in the Inflammatory Response in Diabetes

RAID
Start date: September 2023
Phase: N/A
Study type: Interventional

The primary aim of the present study is to study the effect of adrenaline administration on inflammatory parameters (e.g. leukocyte phenotype, cytokines, inflammatory proteins). Secondary objectives consist of the effect of adrenaline on atherogenic parameters. - All participants will receive intravenous infusion of adrenaline for an hour - We will draw blood at 7 time points, not including screening - Participants will be asked to return for a total of 4 times Researchers will compare 2 groups, healthy individuals versus people with diabetes type 1 to see if the inflammatory reaction to adrenaline differs between these two groups.

NCT ID: NCT05979246 Not yet recruiting - Diabetes Clinical Trials

Effect of the Superhydrophilic Surface of Lance CLEAR Implants on the Marginal Bone Loss and Survival in Diabetic and Non Diabetic Patients

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

The aim of this clinical, prospective study involving implants with a superhydrophilic surface is to compare the changes of the peri-implant tissues and the survival rate between diabetics and non-diabetics patients, after 12 months of loading. hypothesis: It is not expected to find any short-term differences in failures and marginal bone loss between the diabetic and non-diabetic patients. On the longer term higher marginal bone loss may affect the diabetic group 40 patients who are planned to undergo implant installation will be enrolled in the study. The patients will be divided into 2 groups: - Test group - 20 patients diagnosed with type 2 diabetes with 10>HbA1C>7.5% values - Control group - 20 non-diabetic patients.

NCT ID: NCT05977218 Not yet recruiting - Clinical trials for Diabetes Mellitus, Type 2

DIATEST - mHealth and Type 2 Diabetes Mellitus

DIATEST
Start date: January 1, 2024
Phase: N/A
Study type: Interventional

Dietary modification is effective in the prevention and treatment of type 2 diabetes mellitus (T2DM). However, the access to dieticians in primary care is limited. While mHealth tools have been shown to improve diet and clinical management of patients with T2DM, there are currently no mobile health (mHealth) tools that are effective in improving diet and clinical management of T2DM in Sweden. The aim of this project is to study the effect of the FoodSwitch app, an mHealth intervention for patients with T2DM.