Exercise in Pregnancy and Risk of Postpartum Depression

Depression Clinical Trial

Official title:

Exercise in Pregnancy and Risk of Postpartum Depression

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT06355375
• Other study ID #: 02.24
• Status: Recruiting
• Phase: N/A
• Start date: March 22, 2024
• Est. completion date: December 1, 2025

Study information

• Verified date: April 2024
• Source: Federico II University
• Contact: Gabriele Saccone, MD
• Phone: 3394685179
• Email: gabriele.saccone.1990[@]gmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The prevalence of postpartum depression (PPD) varies between 11.9% and 19.2% during the perinatal period. PPD refers to minor and major depression incidents that occur during pregnancy or shortly after (up until 12 months after birth). The symptoms of PPD embrace feeling sad or having a depressed mood, being uninterested in the new-born, unreasonable crying and fear of injuring or harming the baby. Consequently, PPD can negatively impact the mother's well-being and the baby's development. The impact on a child can be short for cognitive and motor development . Although medication is a feasible alternative, many women have constraints due to continuing breastfeeding. Therefore, exercise can be an alternative that could help to deal with PPD. Exercise can be used as a preventive or treatment of mild depression at an early stage and as an addition to a treatment plan for major depressive disorder. Exercising during pregnancy and postpartum improves psychological health and also benefits physical fitness, weight gain control and the prevention or reduction of musculoskeletal discomfort and pain. Therefore, the American College of Obstetrics and Gynaecologists has recommended that women during pregnancy and postpartum engage in moderate-intensity physical activity almost every day for 30 min a day

Description:

The prevalence of postpartum depression (PPD) varies between 11.9% and 19.2% during the perinatal period. PPD refers to minor and major depression incidents that occur during pregnancy or shortly after (up until 12 months after birth). The symptoms of PPD embrace feeling sad or having a depressed mood, being uninterested in the new-born, unreasonable crying and fear of injuring or harming the baby. Consequently, PPD can negatively impact the mother's well-being and the baby's development. The impact on a child can be short for cognitive and motor development . Although medication is a feasible alternative, many women have constraints due to continuing breastfeeding. Therefore, exercise can be an alternative that could help to deal with PPD. Exercise can be used as a preventive or treatment of mild depression at an early stage and as an addition to a treatment plan for major depressive disorder. Exercising during pregnancy and postpartum improves psychological health and also benefits physical fitness, weight gain control and the prevention or reduction of musculoskeletal discomfort and pain. Therefore, the American College of Obstetrics and Gynaecologists has recommended that women during pregnancy and postpartum engage in moderate-intensity physical activity almost every day for 30 min a day

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 398
• Est. completion date: December 1, 2025
• Est. primary completion date: January 1, 2025
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 20 Years to 40 Years

Eligibility

Inclusion Criteria:

• singleton gestation

• low risk pregnancy

• age between 20 and 40

Exclusion Criteria:

• high risk pregnancy

• multiple gestation

• prior post partum depression

• any psychiatric disase

• controindication for exercise

• lung or heart disease

• prior preterm birth

• IVF pregnancy

• women who already perform agonistic sport activity

Related Conditions & MeSH terms

• Depression
• Depression, Postpartum
• Depressive Disorder
• Pregnancy Related

Intervention

Behavioral:
• exercise in pregnancy
aerobic exercise

Locations

Country	Name	City	State
Italy	Gabriele Saccone	Naples

Sponsors (1)

Lead Sponsor	Collaborator
Federico II University

Country where clinical trial is conducted

Italy, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	edinburgh depression scale	Edinburgh Postnatal Depression Scale (EDPS)	3 months after delivery
Secondary	Postpartum depression	DSM-5 (SCID-5)	3 months after delivery
Secondary	preterm birth	defined as delivery before 37 weeks of gestation	37 weeks of gestation