Development and Relationship Between Resilience and Anxiety and Depression in Elderly Gastric Cancer Survivors

Depression Clinical Trial

Official title:

Exploring the Developmental Changes and Relationship Between Resilience and Anxiety and Depression in Elderly Gastric Cancer Survivors: Based on Latent Growth Modeling and Cross-lagged Modeling

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06033716
• Other study ID #: 2020-273-1
• Status: Completed
• Start date: March 1, 2021
• Est. completion date: October 31, 2022

Study information

• Verified date: September 2023
• Source: Nanjing Medical University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This study will explore the dynamic interaction between mental resilience, anxiety and depression in elderly patients with gastric cancer 1 year after surgery, in order to better understand the role of these two factors in patients' mental health, and provide accurate insights for clinical practice and targeted psychological support strategies.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 412
• Est. completion date: October 31, 2022
• Est. primary completion date: October 31, 2022
• Gender: All
• Age group: 60 Years and older

Eligibility

Inclusion Criteria:

• diagnosed with gastric cancer by endoscopy or pathology

• age =60 years old

• radical gastrectomy was proposed

• be able to communicate simply in writing and verbal

Exclusion Criteria:

• received preoperative radiotherapy or chemotherapy;

• combined with other sites of malignant tumors;

• combined with severe heart, liver, lung and renal insufficiency;

• recent using hormones, immunosuppressants;

• with physical disabilities.

Related Conditions & MeSH terms

• Anxiety
• Anxiety Disorders
• Depression
• Depressive Disorder
• Resilience
• Stomach Neoplasms

Intervention

Other:
• Measurement correlation variable
resilience and anxiety and depression

Locations

Country	Name	City	State
China	Yinning Guo	Nanjing	Jiangsu

Sponsors (1)

Lead Sponsor	Collaborator
Nanjing Medical University

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	resilience	The Chinese version of 10-item Connor-Davidson Resilience Scale (CD-RISC-10), translated and revised by Chinese scholars, was used in this study. Cronbach's alpha for the Chinese version was 0.855, indicating good internal consistency. It was also applied to cancer patients in China. Each of which was scored on a 5-point Likert scale, ranging from 1 to 5 points, from "Never" to "Almost always", with higher scores representing a higher level of psychological resilience.	immediately after surgery (T1), three month post-surgery (T2), six months post-surgery (T3), 12 months post-surgery (T4)
Primary	anxiety	Chinese version of the Hospital Anxiety and Depression Scale (HADS) was used in this study to assess the anxiety and depression of elderly cancer patients, which was developed by Zigmond AS et al. The scale consists of 14 items, including anxiety and depression subscales. Each item is rated on a 4 point scale, and the scores of the anxiety and depression scales range from 0 to 21 points. The Cronbach's a coefficient of the HADS for this study was 0.85.	immediately after surgery (T1), three month post-surgery (T2), six months post-surgery (T3), 12 months post-surgery (T4)
Primary	depression	Chinese version of the Hospital Anxiety and Depression Scale (HADS) was used in this study to assess the anxiety and depression of elderly cancer patients, which was developed by Zigmond AS et al. The scale consists of 14 items, including anxiety and depression subscales. Each item is rated on a 4 point scale, and the scores of the anxiety and depression scales range from 0 to 21 points. The Cronbach's a coefficient of the HADS for this study was 0.85.	immediately after surgery (T1), three month post-surgery (T2), six months post-surgery (T3), 12 months post-surgery (T4)