Study of Rotatory Vestibular Tests in Major Depression Patients and Healthy Control Subjects.

Depression Clinical Trial

Official title:

Study of Rotatory Vestibular Tests in Major Depression Patients and Healthy Control Subjects.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03421847
• Other study ID #: ROTDEPR01
• Status: Completed
• Phase: N/A
• First received: January 29, 2018
• Last updated: February 2, 2018
• Start date: July 1, 2005
• Est. completion date: December 15, 2006

Study information

• Verified date: February 2018
• Source: Vest Brain,Centro de Estudios Neurovestibulares
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This study evaluates the vestibular activity in major depression patients and healthy controls using the rotatory test and electronystagmography.

Description:

Previous studies showed abnormal vestibular activity in major depression patients using caloric vestibular tests. The present study investigates the vestibular response to vestibular rotatory tests in major depression subjects and healthy controls.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 41
• Est. completion date: December 15, 2006
• Est. primary completion date: December 15, 2006
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• male and females adults (18 years or older)

• met the Diagnosing and Statistical Manual of Mental Disorders (DSM-IV-R, American Psychiatric Association, 2000) criterion.

• had a score of 12 or more in the Hamilton Rating Scale, 21 items for Depression.

• with or without actual pharmacological treatment, except benzodiazepines that were suspended 24 hours before the rotary test when corresponding.

Exclusion Criteria:

• pregnant women

• neurologic disorders.

Related Conditions & MeSH terms

• Depression
• Depressive Disorder
• Depressive Disorder, Major
• Ear Diseases
• Vestibular Diseases
• Vestibular Disorder

Intervention

Diagnostic Test:
• Rotatory vestibular test
We will measure Depression and Healthy subjects vestibular activity by Rotatory Vestibular tests

Locations

Country	Name	City	State
n/a

Sponsors (2)

Lead Sponsor	Collaborator
Vest Brain,Centro de Estudios Neurovestibulares	Centro de Medicina Aeroespacial.

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Vestibular Activity	The primary outcome corresponds to the vestibular activity. The vestibular stimulation provided by the rotatory chair is sensed by the inner ear´s vestibular receptors and generates reflex ocular movements(Vestibulo Ocular Reflex) registrated by electronystagmography. The main outcome corresponds to the asymmetry of the vestibular activity between both ears.	Vestibular rotatory test for each participant is about 50- 60 minutes. One rotatory test per participant.