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Deglutition Disorders clinical trials

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NCT ID: NCT02718963 Completed - Clinical trials for Deglutition Disorders

Treatment of Dysphagia by Using a Synchronized Electrical Stimulation Device

Start date: July 15, 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the synchronized electrical stimulation device effective in the treatment of dysphagia.

NCT ID: NCT02674412 Completed - Clinical trials for Ineffective Esophageal Motility

Buspirone for Functional Dysphagia

Start date: February 2016
Phase: N/A
Study type: Interventional

This study evaluates the utility of buspirone in patients who have a diagnosis of functional dysphagia. All participants will be randomized to receive either a placebo pill or buspirone. Subsequently, we will evaluate whether their swallowing is improved. Participants who were randomized to receive placebo will then receive buspirone and those who were receiving buspirone will receive placebo. We will again evaluate whether their swallowing improved.

NCT ID: NCT02661256 Completed - Clinical trials for Deglutition Disorders

Effect of Nasal Continuous Positive Airway Pressure on The Pharyngeal Swallow in Neonates

Start date: June 2014
Phase: N/A
Study type: Interventional

Oral feeding of neonates while on nasal continuous positive airway pressure (NCPAP) is a common practice in many neonatal intensive care units (NICU) all over the country. However the safety of such practice has never been established. The Investigators hypothesize that mechanoreceptors, which should perceive sensory input from the liquid bolus, may be altered by the reception of pressurized airflow provided by the NCPAP, hence increase risk of aspiration. In this study, changes in the pharyngeal phase of swallowing were identified using video fluoroscopic swallow studies (VFSS) for infants while on NCPAP as compared to off NCPAP.

NCT ID: NCT02647931 Completed - Clinical trials for Muscle Tension Dysphagia

The Role of Therapy for Muscle Tension Dysphagia

Start date: November 2015
Phase: N/A
Study type: Interventional

Muscle tension dysphagia is a novel diagnostic taxonomy describing a subset of patient population with reported dysphagia who exhibit normal oropharyngeal and esophageal swallowing function as evidenced by videofluoroscopic swallow study. These patients also demonstrate abnormal supraglottic muscle tension during laryngoscopy as well as signs of laryngeal hypersensitivity and laryngopharyngeal reflux. Treatment of these patients with Proton Pump Inhibitor (PPI) therapy is a common practice however voice therapy invention targeting the unloading of the supraglottic muscle tension has been shown to be highly effective in symptom resolution per the investigators' clinical experience. The study is designed to answer efficacy of treatment being offered to patients with muscle tension dysphagia.

NCT ID: NCT02627664 Completed - Parkinson's Disease Clinical Trials

Study of Dysarthria, Swallowing Disorders and Respiratory in Parkinson's Disease

ProdDiGYPark
Start date: March 2011
Phase: N/A
Study type: Observational

The investigators prospectively enrolled 64 early PD patients (less than 3 years after the first symptom) in order to prospectively assess the natural history of non-dopaminergic symptoms.

NCT ID: NCT02583360 Completed - Dysphagia Clinical Trials

Mechanisms and Management of Infant Dysphagia

Start date: October 2, 2015
Phase: N/A
Study type: Interventional

The purpose of the investigator's study is to evaluate the causes of feeding difficulty in infants. New treatments can be possible only if the cause is known. In this study, the investigator plans to evaluate the movement of the muscles in an infant's mouth, throat (pharynx) and food pipe (esophagus) that are responsible for moving the food down into the stomach and that help protect an infants airway.

NCT ID: NCT02539394 Completed - Dysphagia Clinical Trials

Effect of Topical Corticosteroids on Dysphagia in Anterior Cervical Discectomy and Fusion

Start date: August 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to determine what effect intraoperative topical steroids have on reducing swallowing difficulty following Anterior Cervical Discectomy and Fusion surgery.

NCT ID: NCT02530216 Completed - Constipation Clinical Trials

Evaluating the Impact of Automated Evaluation of Gastrointestinal Symptoms (AEGIS) on Clinical Outcomes

AEGIS
Start date: April 10, 2017
Phase: N/A
Study type: Interventional

Healthcare delivery now mandates shorter visits with higher documentation requirements, undermining the patient-provider interaction. Electronic health records (EHRs) have the potential to improve outcomes and quality of care in this pressured environment, and are endorsed by the Patient Protection and Affordable Care Act (ACA) and Health Information Technology for Economic and Clinical Health (HITECH) Act as an important mechanism to support value-based healthcare. However, EHR systems were principally designed to support the transactional needs of administrators and billers, less so to nurture the relationship between patients and their providers. The purpose of this research is to identify ways to use EHRs to support clinical gastroenterologists and their patients while meeting the meaningful use requirements of the HITECH Act. To improve clinic visit efficiency and meet criteria for meaningful use, investigators developed a patient-provider portal (P3) that systematically collects patient symptoms using a computer algorithm called Automated Evaluation of Gastrointestinal Symptoms (AEGIS). AEGIS utilizes computerized adaptive testing (CAT) to guide patients through questions drawn from a library of over 300 symptom attributes measuring the timing, severity, frequency, location, quality, and character of their GI symptoms, along with relevant comorbidities, family history, and alarm features. The system then automatically "translates" the patient report into a full narrative HPI available for use by GI providers in an EHR. In a cross-sectional study in the American Journal of Gastroenterology comparing AEGIS versus physician-documented HPIs, investigators found that blinded physician reviewers perceived that AEGIS HPIs were of higher overall quality, better organized, and more succinct, comprehensible, complete and useful compared to HPIs written by physicians during usual care in academic GI clinics. In the current study, investigators aim to evaluate computer-generated HPIs prospectively on a wider scale in diverse academic and community-based settings. Moreover, investigators aim to test an enhanced AEGIS intervention that ties patient HPIs to an individualized "education prescription" which guides the patient through a library of multi-media educational materials on GI symptoms, conditions, and treatments.

NCT ID: NCT02522351 Completed - Stroke Clinical Trials

Reduction of Aspiration Through Cohesive Thin Liquids (CTL) in Patients With Mild Oropharyngeal Dysphagia

Start date: June 2015
Phase: N/A
Study type: Interventional

The aim of the trial is to identify any systematic effect of cohesiveness on the efficacy of swallowing in patients having dysphagia problems.

NCT ID: NCT02512224 Completed - Clinical trials for Deglutition Disorders

Comparison of Outcomes Between Parenteral and Enteral Nutrition

Start date: April 2012
Phase: N/A
Study type: Observational

Short-term outcomes of parenteral and enteral nutrition for patients unable to eat normally were compared and analyzed.