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Deglutition Disorders clinical trials

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NCT ID: NCT05970406 Enrolling by invitation - Clinical trials for Dysphagia Following Cerebrovascular Accident

High Intensity Dysphagia Rehab for Acute Ischemic Stroke Patients

Start date: November 30, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to determine a standardized protocol for swallowing therapy and this protocol's effects on recovery after a stroke

NCT ID: NCT05497219 Enrolling by invitation - Clinical trials for Dysphagia, Oropharyngeal

Reference Values for Videofluoroscopic Measures of Swallowing

NIA_RV
Start date: November 15, 2022
Phase: N/A
Study type: Interventional

Dysphagia (swallowing impairment) is a serious health condition seen in many age-related disease and injury processes. Although videofluoroscopy (VF) is an international "gold standard" dysphagia diagnostic exam, there is a paucity of available normative physiologic VF reference values in healthy adults across the age span to guide interpretation of these examinations. In this project, the investigators will extend previous work on the quantitative measurement of swallowing physiology from VF examinations to establish reference values for swallowing in healthy adults, and to identify clinical decision point values for differentiating healthy swallowing across the age span from disordered swallowing in several high-risk clinical populations to study dysphagia.

NCT ID: NCT05325658 Enrolling by invitation - Clinical trials for Oropharyngeal Dysphagia

Influence of Modified Diet, Exercise and Electrical Swallowing Muscle Stimulation on Swallowing Function and Quality of Life in Elderly Patients With Oropharyngeal Dysphagia

Start date: May 21, 2021
Phase:
Study type: Observational

Tasks of biomedical research: 1. To determine the severity of oropharyngeal dysphagia and the risk of aspiration in elderly patients. 2. To evaluate the quality of life of older patients with oropharyngeal dysphagia by performing validation of the Lithuanian version of the quality of life questionnaires in patients with oropharyngeal dysphagia. 3. To evaluate the severity of oropharyngeal dysphagia in elderly patients, the risk of aspiration, and quality of life after interventions. Data on the sex, age and disease of the swallowing disorder will be collected. No processing of other personal data and health indicators is planned. All data will be collected in questionnaires. The data will be depersonalized by giving the patient a code. The results and conclusions of the research will be described in the doctoral dissertation and will be used for scientific articles.

NCT ID: NCT05249270 Enrolling by invitation - Anxiety Clinical Trials

Online Parent-Report Evaluation of the Effects of Processed Music

Start date: March 22, 2020
Phase:
Study type: Observational

The study aims to examine effectiveness of the Safe and Sound Protocol (SSP) on sensory, digestive, and eating behaviors in children currently receiving therapy.

NCT ID: NCT04942847 Enrolling by invitation - Prospective Study Clinical Trials

Application of Cognitive Combined Sucking Task Training in Dysphagia After Stroke

Start date: October 1, 2020
Phase: N/A
Study type: Interventional

this topic research, on the basis of traditional swallowing training to develop a set of scientific and advanced type of swallowing disorder in patients with stroke rehabilitation training of the new strategy, combined with cognitive training and sucking training for swallowing disorder in patients with cerebral apoplexy and to provide professional, systematic and comprehensive rehabilitation guidance, promote patients early recovery and return to society.

NCT ID: NCT04928079 Enrolling by invitation - Parkinson Disease Clinical Trials

6-year Follow-up of Dysphagia in Patients With Parkinson's Disease

Start date: January 1, 2014
Phase:
Study type: Observational

We recruited 116 patients with idiopathic PD who were from the Neurology clinic of the Second Affiliated Hospital of Zhejiang University, School of Medicine from January 2014 to November 2014. Perform videofluroscopic swallowing study and psychiatric and neurological evaluations and followed up after 6 years.

NCT ID: NCT04132271 Enrolling by invitation - Clinical trials for Oropharyngeal Dysphagia

Swallowing and Nutritional Treatment on OD Patients

OD
Start date: December 3, 2019
Phase: N/A
Study type: Interventional

Dysphagia is a difficulty during the swallowing process (transportation food from the mouth to the stomach. Oropharyngeal Dysphagia (OD) is diagnosed by videofluoroscopy and faringolaringoscopy. OD threatens the efficacy and safety of swallowing, contributing to an increased risk of aspiration and pneumonia. There are different interventions aimed to change and improve the physiology of swallowing; however, OD can be an important predictor of the progression of malnutrition in different types of patients. Malnutrition is defined as an acute or chronic disease whereby an energy imbalance, lack of energy, protein or other nutrients causes measurable and adverse effects on body composition, functional and clinical outcomes. In addition, it leads to a decrease in the quality of life. Objective: To establish a strategy of nutritional treatment and swallowing rehabilitation in patients with dysphagia. Hypothesis: An adequate nutritional intervention in content and consistency, combined with swallowing rehabilitation in patients with dysphagia, will improve the nutritional status and clinical evolution of patients with dysphagia.

NCT ID: NCT04074356 Enrolling by invitation - Dysphagia Clinical Trials

Non-invasive Markers of Esophageal Function in Adults

Start date: September 4, 2019
Phase: N/A
Study type: Interventional

The investigator proposes to study electrical activity reflective of esophageal motility in adults noninvasively by the use of multichannel electroesophagogram (EESG) and magnetoesophagogram (MESG) recordings.

NCT ID: NCT02935946 Enrolling by invitation - Clinical trials for Deglutition Disorders

Cold Liquids Fed to Preterm Infants: Efficacy and Safety After 10 Minutes of Exposure

Start date: October 2016
Phase: N/A
Study type: Interventional

A previous study revealed that dysphagia preterm infants show statistically significant improvements in their swallowing mechanism when fed cold liquid barium when compared to room temperature liquid barium. The previous study was the first to identify these positive effects, although, only assessed 5 cold liquid swallows, immediately after the room temperature condition. This limited data set restricts the efficacy and safety of using cold liquids in clinical practice, emphasizing the need for further information. The present study aims to objectively assess the influence of cold liquid on the pharyngeal swallow mechanism in preterm infants with dysphagia after 10 minutes of a cold liquid feeding. The investigators will utilize videofluoroscopic swallow studies (VFSS) to analyze the frequency and severity of pharyngeal swallowing deficits during room temperature swallows and compare it to cold liquid swallows at various time points within a 10 minute feeding. Safety measures will also be obtained, such as participant axillary body temperature and gastric content temperature, to identify indicators for the development of cold stress.

NCT ID: NCT01697891 Enrolling by invitation - Clinical trials for Head and Neck Cancer

A Pilot Study of ALTENS in Improving Dysphagia Induced by IMRT for Head and Neck Cancers

Start date: October 2012
Phase: Phase 1/Phase 2
Study type: Interventional

Study hypothesis: ALTENS techniques, administered within the first 3 months after radiation completion, can improve radiation-induced dysphagia and associated symptoms in head and neck cancer patients. This beneficial effect is mediated by the reduction of chronic inflammatory response of swallowing musculature to radiation, consequently a reduction in muscle fibrosis. Primary study objective: To evaluate the effectiveness of ALTENS in relieving radiation-induced dysphagia. Eating Assessment Tool (EAT-10) scores will be used for this primary study endpoint.