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NCT ID: NCT04568395 Completed - Inflammation Clinical Trials

Acute Effects of TCIG vs ECIG in PLWH

Start date: October 1, 2020
Phase: N/A
Study type: Interventional

Randomized controlled trial of acute use of electronic cigarette or tobacco cigarette on parameters of ventricular repolarization and inflammation/oxidative stress.

NCT ID: NCT04568382 Completed - Clinical trials for Diabetes Mellitus, Type 2

Diabetes Communication and Treatment Burden

Start date: October 12, 2020
Phase: N/A
Study type: Interventional

The objective of this proposal is to pilot test two types of pre-visit planning, where clinical staff reviews charts and talks to patients before their doctors appointments, to reduce the burden of diabetes care on the patient without increasing the visit workload during busy primary care clinics.

NCT ID: NCT04568356 Completed - SARS CoV-2 Clinical Trials

A Clinical Evaluation of COVID-19 Rapid Point of Care Antigen Tests

Start date: April 24, 2020
Phase: N/A
Study type: Interventional

The current standard of care for diagnosis of Severe Acute Respiratory Syndrome associated Coronavirus -2 (SARS-CoV-2 ) infection involves sample collection to be prepared and measured via real time-polymerase chain reaction (RT-PCR). This process is often time consuming depending on the level of automation within the laboratory processing the samples. In many cases, sample turn-around times can take hours to several days. A rapid assay that does not require the sophisticated laboratory equipment and techniques could provide a significant advantage to the way practitioners screen and ultimately treat patients. Moreover, the collection of samples from the nasal nares should prove useful and less invasive. The study aims to validate the use of nasal swabs and also to validate the antigen test using nasal swabs.

NCT ID: NCT04568213 Completed - Cataract Clinical Trials

Hypochlorous Acid Disinfection Prior to Cataract Surgery

Start date: October 29, 2020
Phase: Phase 3
Study type: Interventional

Antibiotics are commonly utilized to reduce the bacterial population of the eye prior to surgery with the assumption that this reduces the risk of endophthalmitis, although it is not clear if this actually occurs. This study will investigate the use of Hypochlorous Acid, a commercially available over the counter (OTC) medication to see if this will reduce the bacterial population prior the cataract surgery.

NCT ID: NCT04568122 Completed - Covid19 Clinical Trials

Rapid Turnaround, Home-based Saliva Testing for COVID-19

Start date: November 20, 2020
Phase: N/A
Study type: Interventional

The aim of the study is to demonstrate the feasibility and validity of a saliva based home surveillance monitoring test for SARS-CoV-2 infection. Participants will be asked to carry out as many tests as are included in the bag they are provided, on a daily basis until they are used up.

NCT ID: NCT04568083 Completed - Clinical trials for Myocardial Infarction (MI)

Patient Characteristics, Persistence to Treatment and Outcome Events in Patients Treated With Ticagrelor 60 mg After Myocardial Infarction in Real-world Clinical Practice

ALETHEIA
Start date: September 25, 2020
Phase:
Study type: Observational

This is an observational study based on secondary data extracted from multiple register-based data sources in the US and Europe (Sweden, United Kingdom, Italy, Germany). The study will include patients initiating treatment with ticagrelor 60 mg after a myocardial infarction in real-world clinical practice, and describe their patient characteristics and duration of treatment. If the a priori threshold of 5,000 person-years on treatment with ticagrelor 60 mg is met, outcome events (bleeding and cardiovascular events) will also be analysed and described.

NCT ID: NCT04567888 Completed - Clinical trials for Stress, Psychological

Testing a Digital Intervention for Adolescents

Start date: June 3, 2021
Phase: N/A
Study type: Interventional

Teen participants (ages 13-17) will be randomly assigned to either an experimental (the Happify Teens digital platform), or a waitlist control group. The study includes an 8-week intervention period and a 1-month follow up period.

NCT ID: NCT04567849 Completed - Emergency Treatment Clinical Trials

Decreasing ED Utilization by Nudging Patients to Call Their Providers

Start date: November 16, 2021
Phase: N/A
Study type: Interventional

In the present study, patients will be sent a message shortly after completing a medical procedure that informs or reminds them that they can reach out to Geisinger, and how to do it, if they have any medical issues or concerns. Researchers will assess if such messages make patients more likely to contact Geisinger with post-procedure medical concerns and decrease emergency department utilization.

NCT ID: NCT04567745 Completed - Alzheimer Disease Clinical Trials

Automated Retinal Image Analysis System (EyeQuant) for Computation of Vascular Biomarkers

Start date: September 29, 2020
Phase: Phase 1
Study type: Interventional

This study aims to provide clinical validation of EyeQuant, a fully automated retinal image analysis system for computation of vascular biomarkers indicative of cognitive disorders, using retinal fundus photographs collected from patients with mild cognitive impairment, Alzheimer's disease, and vascular dementia.

NCT ID: NCT04567667 Completed - Healthy Volunteers Clinical Trials

Study to Assess the Way the Body Absorbs, Distributes, Breaks Down and Eliminates Radioactive BMS-986278 in Healthy Male Participants

Start date: October 15, 2020
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the way the body absorbs, distributes, breaks down and eliminates radioactive BMS-986278 as well as the safety and tolerability of BMS-986278 in healthy male participants.