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NCT ID: NCT04675580 Completed - Clinical trials for Autism Spectrum Disorder

Telehealth Language Intervention for Children With Autism Ages 2-4 Years

Start date: December 23, 2020
Phase: N/A
Study type: Interventional

The main goal of this intervention is to increase caregivers' use of interactive play and communication strategies to improve the child's early sentence development using telemedicine and video-based feedback.

NCT ID: NCT04675255 Completed - Adiposity Clinical Trials

Assessing the Impact of INSTI to PI Switch on Insulin Sensitivity and Fat Metabolism

ADIPOSITY
Start date: January 1, 2021
Phase: N/A
Study type: Interventional

A substudy of TMC114FD2HTX4004 that will perform glucose tolerance testing, adipose testing and MRI scan at baseline, 12 and 24 weeks post switch of ART medications.

NCT ID: NCT04675242 Completed - Blepharitis Clinical Trials

Study Evaluating the Safety and Efficacy of NCX 4251 Ophthalmic Suspension for the Treatment of Blepharitis

Mississippi
Start date: December 14, 2020
Phase: Phase 2
Study type: Interventional

This is a multi-center, randomized, double-masked, placebo-controlled, Phase 2b trial evaluating the safety and efficacy of NCX 4251 (fluticasone propionate nanocrystal) Ophthalmic Suspension 0.1% QD for the treatment of acute exacerbations of blepharitis.

NCT ID: NCT04675151 Completed - Presbyopia Clinical Trials

Safety and Efficacy of Nyxol With Pilocarpine Eye Drops in Subjects With Presbyopia

Start date: February 15, 2021
Phase: Phase 2
Study type: Interventional

The objectives of this study are: To evaluate the efficacy of Nyxol + Pilocarpine to improve DCNVA in subjects with presbyopia

NCT ID: NCT04674852 Completed - Clinical trials for Breast Neoplasm Female

Mayo Designed Soft Tissue Ultrasound-Detectable Marker

Start date: November 2, 2020
Phase: N/A
Study type: Interventional

Researchers are trying to determine if the Mayo marker is easily seen with ultrasound making it easier, faster, and more accurate for preoperative localization of the biopsied positive lymph node.

NCT ID: NCT04674761 Completed - Alagille Syndrome Clinical Trials

Efficacy and Safety of Odevixibat in Patients With Alagille Syndrome

ASSERT
Start date: March 19, 2021
Phase: Phase 3
Study type: Interventional

Double-blind, randomized, placebo-controlled, Phase 3 study to investigate the efficacy and safety of odevixibat compared to placebo in Patients with Alagille Syndrome.

NCT ID: NCT04674436 Completed - Sedentary Behavior Clinical Trials

Can a 6-minute Walking or Resting Break Improve Executive Function in Gamers.

Start date: July 24, 2020
Phase: N/A
Study type: Interventional

This study will ask ranked first person shooters in esports to participate on three separate days from their home computer to test executive function prior tp play and following two hours of play. One testing day will incorporate a 6 minute walk break, another day will incorporate a 6 minute rest break, and the third day will be continuous play. Executive tests will be administered electronically prior to game play and post game play.

NCT ID: NCT04674358 Completed - Dry Eye Clinical Trials

The TRANQUILITY Trial: Clinical Trial to Assess the Efficacy and Safety in Subjects With Dry Eye Disease

Start date: November 21, 2020
Phase: Phase 2/Phase 3
Study type: Interventional

The TRANQUILITY Trial: Multi-Center Randomized, Double-Masked, Parallel Design, Vehicle-Controlled Phase 2/3 Clinical Trial to Assess the Efficacy and Safety of 0.25% Reproxalap Ophthalmic Solution Compared to Vehicle in Subjects with Dry Eye Disease.

NCT ID: NCT04674228 Completed - Clinical trials for Familial Adenomatous Polyposis

Review of Post-Study Clinical Endoscopy Reports in Follow Up to MAY2016-07-01

Start date: May 7, 2021
Phase:
Study type: Observational

This study reviews post study clinical endoscopy reports in follow up to patients who participated in MAY2016-07-01 with weekly erlotinib for familial adenomatous polyposis. Reviewing follow up medical records may help researchers examine the extent of rapid progression of familiar adenomatous polyposis disease burden after discontinuation of weekly erlotinib.

NCT ID: NCT04673994 Completed - Stroke Clinical Trials

Blood Flow Response and Acute INterval Exercise

BRAIN
Start date: December 9, 2020
Phase:
Study type: Observational

The objective of this project is to study the cerebrovascular response to a single bout of high intensity interval exercise (HIIT) in 25 individuals with chronic stroke compared to 25 age- and sex- matched healthy controls (CON). We will enroll 25 young healthy adults (CONyoung) as a reference group. Our hypothesis is that the cerebrovascular response in individuals with chronic stroke will be significantly lower: 1) during a single bout of HIIT, and 2) during the recovery immediately following and 30 minutes after HIIT, compared to CON. This study has 2 visits at the University of Kansas Medical Center Research in Exercise and Cardiovascular Health Laboratory. For the first visit, we will perform questionnaires about heart health, physical activity and overall health. Participants will then complete a submaximal exercise test on a seated stepper. Participants will also have a familiarization session to practice HIIT. The second visit will include cerebrovascular measures before, during, immediately after, and 30 minutes after performing HIIT.