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NCT ID: NCT05811247 Active, not recruiting - OSA Clinical Trials

Parallel Arm Trial of AD109 and Placebo With Patients With OSA (LunAIRo)

Start date: August 28, 2023
Phase: Phase 3
Study type: Interventional

This is a Phase 3 Randomized Double-Blind Placebo-Controlled 1-year Parallel-Arm Study to Compare a Fixed Dose Combination of AD109 to Placebo in Obstructive Sleep Apnea.

NCT ID: NCT05809934 Active, not recruiting - Clinical trials for Nonalcoholic Steatohepatitis

A Study to Evaluate AZD2693 in Participants Who Are Carriers of the PNPLA3 148M Risk Allele With Non-cirrhotic Non-alcoholic Steatohepatitis With Fibrosis

FORTUNA
Start date: March 15, 2023
Phase: Phase 2
Study type: Interventional

A Study to Evaluate the Efficacy, Safety and Tolerability of AZD2693 given by subcutaneous injection in adult participants with non-cirrhotic non-alcoholic steatohepatitis with fibrosis and who are carriers of the PNPLA3 148M Risk Allele

NCT ID: NCT05809531 Active, not recruiting - C3 Glomerulopathy Clinical Trials

An Open-Label, Nonrandomized, Multicenter Extension Study to Evaluate the Long-term Safety and Efficacy of Pegcetacoplan in Participants With C3 Glomerulopathy or Immune-Complex Membranoproliferative Glomerulonephritis

VALE
Start date: May 29, 2023
Phase: Phase 3
Study type: Interventional

This study is designed as a long-term extension to Study APL2-C3G-310, and is being conducted to establish the long-term safety and efficacy of pegcetacoplan in patients with C3 glomerulopathy (C3G) or immune-complex membranoproliferative glomerulonephritis (IC-MPGN).

NCT ID: NCT05809453 Active, not recruiting - Exercise Clinical Trials

Intranasal Cocaine and Temperature Regulation During Exercise

Start date: September 1, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

Assess the effects of intranasal cocaine on temperature regulation and whole-body sweat rate during exercise in warm environmental conditions.

NCT ID: NCT05809115 Active, not recruiting - Depression Clinical Trials

Addressing Caregiver Wellbeing and Improving Child Development

Start date: June 14, 2023
Phase:
Study type: Observational

The goal of this study is to study whether the investigators can improve maternal child bonding and ultimately development in young children by helping caregivers with food insecurity and mental health needs. Both food insecurity and maternal depression has been linked to delays in development for children. This is a clinical trial in the mothers of hospitalized children 0-3 years of age. Participants who consent will complete a screening survey on social needs, food insecurity, stress, depression, and anxiety. There is not a comparison group. All caregivers who are identified as having food insecurity and/or anxiety or depression will receive study interventions.

NCT ID: NCT05808699 Active, not recruiting - Clinical trials for Diabetic Retinopathy

Camera Qualification Study

Start date: March 3, 2023
Phase:
Study type: Observational

A multi-center study to evaluate the performance of an automated device for the detection of diabetic retinopathy with the use of an additional fundus camera with IDx-DR.

NCT ID: NCT05806840 Active, not recruiting - Substance Use Clinical Trials

Rapid Adaptation to Prevent Drug Use

RAPD
Start date: September 6, 2023
Phase: N/A
Study type: Interventional

Using a 2-group, mixed method cluster randomized trial design, this study will compare standard implementation versus RAPD implementation strategy in Michigan Middle Schools

NCT ID: NCT05806749 Active, not recruiting - Clinical trials for Chronic Kidney Diseases

Immunological Tolerance in Patients With Mismatched Kidney Transplants

Start date: July 7, 2023
Phase: Phase 1
Study type: Interventional

This study seeks to determine if administration of the drug belumosudil (KD025) will be safe and improve transplant tolerance in subjects undergoing combined Human Leukocyte Antigen (HLA) single haplotype-matched related or 0-3 antigen (at A, B, C, DR) HLA mismatched unrelated living donor kidney and hematopoietic stem cell transplantation.

NCT ID: NCT05805722 Active, not recruiting - Cancer Clinical Trials

Comprehensive Tobacco Cessation for Cancer Patients and Survivors

Start date: April 12, 2023
Phase: N/A
Study type: Interventional

The purpose of this research study is to learn how best to incorporate tobacco cessation treatment into clinical care for cancer patients, survivors, and caregivers.

NCT ID: NCT05805657 Active, not recruiting - Sleep Disorder Clinical Trials

Implementing and Sustaining a Sleep Treatment to Improve Community Mental Health Part 2: Train-the-Trainer

Start date: December 14, 2020
Phase: N/A
Study type: Interventional

The train-the-trainer (TTT) approach is a promising method of sustaining training efforts in community mental health centers (CMHCs). This study will test the implementation and effectiveness outcomes of a sleep treatment delivered by CMHC providers who are trained and supervised within CMHCs via TTT. The investigators will test two versions of the sleep treatment, a "Standard" version and an "Adapted" version that has been adapted using theory, data and stakeholder inputs to improve the fit for SMI patients treated in community mental health centers.