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NCT ID: NCT04942665 Completed - Clinical trials for Hepatocellular Carcinoma

Low Dose ICG for Biliary Tract and Tumor Imaging

ICG
Start date: September 15, 2021
Phase: Phase 2
Study type: Interventional

Near-infrared fluorescence (NIRF) imaging after an intravenous injection of indocyanine green (ICG) allows for the intraoperative identification of liver anatomy. The investigators have new data that a much lower dose improves this visualization. Confirmation of this hypothesis would mean that ICG can be administered on the same day of surgery in order to augment real-time intraoperative visualization, thereby providing a safe, feasible, and cost-effective strategy for the surgical treatment of liver disease.

NCT ID: NCT04942613 Completed - Multimorbidity Clinical Trials

Engaging Medically Complex Veterans in Tele-Rehabilitation Using a Biobehavioral Approach

Start date: October 22, 2021
Phase: N/A
Study type: Interventional

The aims of this study are to determine the feasibility and acceptability of a multicomponent telerehabilitation program for medically complex older Veterans and to preliminarily assess participant outcomes (physical activity, physical function, quality of life, loneliness) to the program.

NCT ID: NCT04942561 Completed - Radiology Clinical Trials

VR to Reduce Pain/Anxiety During IV Starts

Start date: April 12, 2017
Phase: N/A
Study type: Interventional

This study aims to test the effectiveness of virtual reality (VR) as a non-pharmaceutical intervention to reduce pain and anxiety in children undergoing peripheral intravenous catheter (PIVC) access in the Department of Radiology and Imaging or the outpatient Infusion Center at CHLA, as measured by self- and proxy-report.

NCT ID: NCT04942548 Completed - Heart Failure Clinical Trials

Reverse HFpEF: Ketogenic Reversal of Heart Failure With Preserved Ejection Fraction Study

Start date: July 25, 2019
Phase: N/A
Study type: Interventional

This protocol is a prospective pilot study utilizing the intervention of a medically supervised, registered nurse and registered diabetes educator coached low-carbohydrate, ketogenic diet to examine the impact it has as a treatment for heart failure with preserved ejection fraction.

NCT ID: NCT04942379 Completed - Childhood Asthma Clinical Trials

Asthma Link: A Real World Application of School Supervised Asthma Therapy

Start date: August 10, 2021
Phase: N/A
Study type: Interventional

The goal of this study is to assess the feasibility of a clinical trial to evaluate the impact and process of deploying school-supervised asthma therapy in a real-world setting for children with poorly controlled asthma (aged 6-17 years).

NCT ID: NCT04942353 Completed - Heart Failure Clinical Trials

Effects of Home-based Exercise Rehabilitation on Healthcare Utilization in HeartMate 3 Patients

MOVE-LVAD
Start date: October 19, 2020
Phase: N/A
Study type: Interventional

To demonstrate that home-based exercise rehabilitation (HER) compared to usual care (UC) results in a significant reduction in healthcare utilization in HeartMate 3 (HM3) left ventricular assist device (LVAD) patients.(defined as rehospitalization, VAD Clinic visits, and ER visits during the 1st year after index discharge following LVAD implantation).

NCT ID: NCT04941807 Completed - Nail Diseases Clinical Trials

Use of Platelet-rich Plasma (PRP) Therapy in Patients With Brittle Nail Syndrome

Start date: March 4, 2021
Phase: Phase 4
Study type: Interventional

The purpose of this study is to assess the efficacy and safety of platelet-rich plasma therapy for brittle nail syndrome

NCT ID: NCT04941755 Completed - Clinical trials for Healthy Participants

A Study to Determine the Effect of Famotidine on the Drug Levels of BMS-986256 in Healthy Participants

Start date: June 25, 2021
Phase: Phase 1
Study type: Interventional

The purpose of this study is to investigate the effect of gastric pH changes induced by famotidine on the drug levels of BMS-986256.

NCT ID: NCT04941742 Completed - Clinical trials for Eosinophilic Esophagitis

The Use of Fractionated Exhaled Nitric Oxide in the Diagnosis and Assessment of Disease Activity of Eosinophilic Esophagitis (Validation Phase)

Start date: September 22, 2020
Phase:
Study type: Observational

The purpose of this study is to evaluate the relationship between fractionated exhaled nitric oxide, peripheral eosinophils, and plasma citrulline and ß-alanine in patients with eosinophilic esophagitis (EoE) compared to those without EoE. The hypothesis is that a combination of elevated fractional exhaled nitric oxide, increased peripheral eosinophils, and elevated plasma citrulline and ß-alanine is associated with active EoE.

NCT ID: NCT04941521 Completed - Clinical trials for Cocaine Use Disorder

Exenatide for Treating Cocaine Use Disorder

Start date: June 24, 2021
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to collect information about whether exenatide (Bydureon) may be safe and helpful as a medication treatment for individuals who want to stop using cocaine. Although exenatide (Bydureon) is approved by the Food and Drug Administration (FDA) for the treatment of type 2 diabetes, it has not been approved by the FDA to treat cocaine use; therefore, it is called an investigational drug.