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NCT ID: NCT05032339 Completed - Clinical trials for Plasma Cell Disorder

Evaluation of the Plasma Cell Disorders Panel on the BD FACSLyric™ Flow Cytometer

Start date: May 4, 2021
Phase:
Study type: Observational

Multi-site, prospective performance study to determine equivalency between the investigational OneFlow PCD panel on the FACSLyric system versus the final clinical diagnosis.

NCT ID: NCT05032313 Completed - Clinical trials for Chronic Lymphoproliferative Diseases (CLPD)

Evaluation of the Chronic Lymphoproliferative Diseases Limited Panel on the BD FACSLyric™ Flow Cytometer

Start date: April 26, 2021
Phase:
Study type: Observational

Multi-site, prospective performance study to determine equivalency between the investigational CLPD Limited Panel on the FACSLyric system versus the final clinical diagnosis.

NCT ID: NCT05032157 Completed - Clinical trials for Chronic Spontaneous Urticaria

A Phase 3 Study of Efficacy and Safety of Remibrutinib in the Treatment of CSU in Adults Inadequately Controlled by H1- Antihistamines

REMIX-2
Start date: December 1, 2021
Phase: Phase 3
Study type: Interventional

The purpose of this study is to establish the efficacy, safety, and tolerability of remibrutinib (LOU064) in adult participants suffering from chronic spontaneous urticaria (CSU) inadequately controlled by H1-antihistamines in comparison to placebo.

NCT ID: NCT05032144 Completed - Healthy Clinical Trials

The Safety and Tolerability of STSA-1002 Following Intravenous Infusion in Healthy Subjects

Start date: September 28, 2021
Phase: Phase 1
Study type: Interventional

A randomized,double-blind,placebo-controlled,single-ascending dose phase Ⅰa study to evaluate the safety,tolerability,pharmacokinetics and pharmacodynamics of STSA-1002 following intravenous infusion in healthy subjects

NCT ID: NCT05031845 Completed - Covid19 Clinical Trials

Low-Dose Chest CT (LDCT) COVID-19 Study

Start date: March 8, 2021
Phase:
Study type: Observational

The goal of our proposed pilot study is to collect low dose CT (LDCT) findings from chest evaluations of a representative sample of 120 symptomatic Caucasian and African American, and Hispanic adults (45 each), stratified by presence of acute respiratory distress syndrome (ARDS) and COVID-19 positivity or negative PCR screening results. These data will provide us with preliminary data on the type and extent of alveolar remodeling by race and by severity of recent infectious respiratory disease. Findings from our study would will help us to determine if a larger multi-site research application to NHLBI or a similar funding agency might be possible and provide critical preliminary data on variation in LDCT findings by COVID-19 attributable respiratory health, race, and other risk factors (e.g., smoking history, comorbidities, and socioeconomic status).

NCT ID: NCT05031806 Completed - Dry Eye Disease Clinical Trials

Evaluation of the Safety, Tolerability and Efficacy of iNexin™ for the Treatment of the Signs and Symptoms Associated With Dry Eye Disease

Start date: September 28, 2021
Phase: Phase 1
Study type: Interventional

The primary objective of this study is to evaluate the safety and tolerability of iNexin™ The secondary objective is to compare the efficacy of iNexin™ to Vehicle for the treatment of the signs and symptoms associated with dry eye disease.

NCT ID: NCT05031741 Completed - Clinical trials for Health Care Utilization

Reducing Adolescent Sexual and Mental Health Disparities by Increasing Access to Telemedicine and Mobile Care

Start date: August 5, 2021
Phase: N/A
Study type: Interventional

Investigators will attend a series of community outreach events that provide/demonstrate telemedicine and the Children's Mercy Mobile Unit which is equipped to provide direct patient care. Investigators will engage up to 12 teen peer leaders to encourage healthcare-seeking behaviors and mobilize their social networks to attend outreach events. At all events, the mobile unit will be available for teens to (a) demonstrate the mobile unit and telehealth experience; (b) learn about Sexual and Reproductive Health/Mental Health (SRH/MH) and local care resources; (c) register for future telemedicine care; (d) acquire free over-the-counter emergency contraception, condoms, and pregnancy tests.

NCT ID: NCT05031663 Completed - Inflammation Clinical Trials

Effect of Almonds on Immune Strength and Response to Flu Vaccination in Overweight Men

Almond Immune
Start date: August 12, 2021
Phase: N/A
Study type: Interventional

This research study will test the effects of almonds on immune functions and immune response to influenza vaccine in overweight middle-aged men

NCT ID: NCT05031624 Completed - Healthy Subjects Clinical Trials

A Phase 1 Study of Subcutaneous CDX-0159 in Healthy Subjects

Start date: August 30, 2021
Phase: Phase 1
Study type: Interventional

This is a study to determine the safety and pharmacokinetics of CDX-0159 administered subcutaneously in healthy subjects.

NCT ID: NCT05031611 Completed - Clinical trials for Psychological Distress

Intuitive Eating for Disordered Eating

IERCT
Start date: April 8, 2020
Phase: N/A
Study type: Interventional

Purpose: Research on intuitive eating is growing, but there are few interventions demonstrating the effect of learning to eat intuitively for people with disordered eating. Young women in particular are at high-risk for developing disordered eating. This study aimed to test the outcomes of a novel intuitive eating intervention for young women with disordered eating. Methods: This study is the first randomized controlled trial introducing intuitive eating to a sample of participants with disordered eating. Participants with current eating disorders were excluded from this study. Women (n=123) ages 18-30 with high levels of disordered eating participated in this study and were randomized to either a treatment (10-week web-based intervention) or control group (10-week waitlist).