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NCT ID: NCT06120972 Recruiting - Ovarian Cancer Clinical Trials

Upfront Maintenance Olaparib in Advanced Ovarian Cancer BRCAwt Patients With Known Homologous Recombination Deficiency

Start date: January 17, 2024
Phase: Phase 2
Study type: Interventional

This is a prospective non-randomized efficacy trial of olaparib maintenance therapy after frontline treatment with platinum-based therapy in advanced ovarian cancer patients with BRCAwt, homologous recombination deficient (HRD) disease.

NCT ID: NCT06120933 Completed - Hair Loss Clinical Trials

A Single-Group Clinical Trial Investigating the Effects of a Hair Vitamin Combination on Hair Growth and Hair Health

Start date: June 15, 2023
Phase: N/A
Study type: Interventional

This clinical trial aims to investigate the effectiveness of two Vitamins Revive hair supplements in promoting hair growth, reducing hair loss, and improving overall hair health. The products under assessment are Hair Nutra Growth and Hair Nutra Boost. The trial will assess the efficacy of the products to induce better hair growth, reduction in hair loss and shedding, increased hair thickness and fullness, and improvement in hair appearance and vitality over a 12-week testing period. Participants will complete study-specific questionnaires at Baseline, Week 4, Week 8, and Week 12. Participants will also provide photos of their hair at Baseline, Week 4, Week 8, and Week 12.

NCT ID: NCT06120881 Recruiting - Type 2 Diabetes Clinical Trials

Precision Dosing of Metformin in Youth With T2D

PRECISE_T2D
Start date: April 1, 2024
Phase: Early Phase 1
Study type: Interventional

The purpose of this study to compare the typically prescribed dose of metformin (1000mg twice a day) with a higher dose of metformin (1350mg twice a day).

NCT ID: NCT06120842 Recruiting - Cataract Clinical Trials

Evaluation of the Bimatoprost Implant System Used in Combination With the SpyGlass Intraocular Lens Compared to Timolol Ophthalmic Solution

Tigris
Start date: October 13, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

This trial is a randomized study to evaluate and compare two doses of the Bimatoprost Implant System used in combination with the SpyGlass IOL to Timolol Ophthalmic Solution in participants with mild to moderate open-angle glaucoma or ocular hypertension undergoing cataract surgery.

NCT ID: NCT06120829 Not yet recruiting - Clinical trials for Cryobiopsy of Peripheral Lymph Nodes

Cryobiopsy for Suspected Malignant Peripheral Lymphadenopathy

COLD SNAP
Start date: December 2023
Phase: N/A
Study type: Interventional

Cryobiopsy of peripheral lymph nodes with suspected malignant potential with comparison to standard core needle biopsy.

NCT ID: NCT06120803 Recruiting - Clinical trials for Locally Advanced Lung Carcinoma

Esomeprazole and Radiation Induced Esophagitis

EERENs
Start date: March 1, 2024
Phase: Phase 2
Study type: Interventional

Thoracic radiation therapy combined with chemotherapy (with or without immunotherapy) is the cornerstone of management in patients with locally advanced non-small cell lung cancer (NSCLC).

NCT ID: NCT06120790 Recruiting - Tracheostomy Clinical Trials

Investigation of a 3 oz Water Protocol on Patients With Tracheostomies

Start date: May 6, 2024
Phase:
Study type: Observational

Examining the validity of a novel 3 oz protocol in patients with tracheostomies as compared to the gold standard of instrumental swallow assessments (Flexible Endoscopic Evaluation of the Swallow or Modified Barium Swallow Study).

NCT ID: NCT06120777 Completed - Healthy Clinical Trials

Clinical Validation for SpO2 Function of Masimo INVSENSOR00069

Start date: November 1, 2023
Phase: N/A
Study type: Interventional

Assess the accuracy of INVSENSOR00069's peripheral oxygen saturation (SpO2) against contemporaneous measurement from arterial blood gas (ABG) analysis.

NCT ID: NCT06120530 Recruiting - Clinical trials for Pelvic Organ Prolapse

Intraperitoneal Bupivacaine for Pelvic Organ Prolapse

Start date: August 15, 2023
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the effects of 30 mL intraperitoneal Bupivacaine without epinephrine 0.25% on postoperative pain control in patients undergoing pelvic organ prolapse repair. The investigators hypothesize that use of intraperitoneal Bupivacaine will decrease postoperative pain scores and opiate consumption in the postoperative period, following pelvic organ prolapse repair.

NCT ID: NCT06120504 Recruiting - Clinical trials for Lymphoma, Non-Hodgkin

A Safety Study of SGN-35T in Adults With Advanced Cancers

Start date: February 29, 2024
Phase: Phase 1
Study type: Interventional

This clinical trial is studying lymphoma. Lymphoma is a cancer that starts in the blood cells that fight infections. There are several types of lymphoma. This study will enroll people who have lymphoma, such as classical Hodgkin lymphoma, peripheral T-cell lymphoma including systemic anaplastic large cell lymphoma, diffuse large B-cell lymphoma, or types of primary cutaneous lymphoma. This clinical trial uses a drug called SGN-35T. The study drug is in testing and has not been approved for sale. This is the first time SGN-35T will be used in people. The study drug will be given as an infusion through a vein. This study will test the safety of SGN-35T in participants with lymphoma. It will also study the side effects of this drug. A side effect is anything a drug does to the body besides treating the disease. This study will have three parts. Parts A and B of the study will find out the best dose and dosing schedule for SGN-35T. Part C will use the dose found in parts A and B to find out how safe SGN-35T is and if it works to treat select lymphomas.