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NCT ID: NCT05045183 Completed - Wound Healing Clinical Trials

A Study to Assess Wound Healing Efficacies of Different Clean, Treat, and Protect Wound Care Regimens Compared to Standard of Care and Untreated

Start date: September 8, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the healing rates of wounds treated with various wound care regimens including antiseptic wound wash, topical antibiotic treatment, adhesive bandages, and/or hydrocolloid bandages.

NCT ID: NCT05045144 Completed - Clinical trials for Respiratory Syncytial Virus Infections

A Phase III Study to Assess the Lot-to-lot Consistency of GSK's Investigational RSV Maternal Vaccine and the Immune Response and Safety of RSV Maternal Vaccine When Given Alone or Co-administered With GSK's Influenza D-QIV Vaccine in Healthy Non-pregnant Women.

Start date: October 26, 2021
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the clinical lot-to-lot consistency of the respiratory syncytial virus (RSV) maternal (RSV MAT) vaccine administered to healthy non-pregnant women 18-49 years of age (YOA). In addition, this study will evaluate immunogenicity, safety and reactogenicity from co-administration of RSV MAT vaccine and GSK's quadrivalent seasonal influenza (Flu D-QIV) vaccine.

NCT ID: NCT05045079 Completed - Clinical trials for Severe Tricuspid Valve Regurgitation (Disorder)

Rhythm Control and Potential Early Surgery for Tricuspid Regurgitation

Start date: January 20, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to understand the clinical impact of non-surgical and surgical treatment in atrial fibrillation induced tricuspid regurgitation (AFTR).

NCT ID: NCT05044793 Completed - Clinical trials for Glaucoma, Open-Angle

A Clinical Study To Assess The Safety And Effectiveness Of The OMNI® Surgical System

Start date: September 30, 2021
Phase:
Study type: Observational

The purpose of this study is to evaluate the long-term safety and effectiveness of the OMNI® Surgical System in subjects who were treated under protocol #06213

NCT ID: NCT05044507 Completed - Ischemic Stroke Clinical Trials

The Efficacy of a Frequency-tuned Electromagnetic Field Treatment in Facilitating the Recovery of Subacute Ischemic Stroke Patients - a Pivotal Study (THE "EMAGINE" STUDY)

BQ5
Start date: December 4, 2021
Phase: N/A
Study type: Interventional

This is a multicenter study that will be conducted at approximately 20 centers. BQ 2.0 is a wearable medical device that produces and delivers non-invasive, extremely-low-intensity and low-frequency, frequency-tuned electromagnetic fields in order to stimulate neuronal networks with the aim of reducing disability and promoting neurorecovery. In this study, BQ 2.0 is intended to reduce disability in adult patients with subacute ischemic stroke, with a moderate to severe disability which includes an upper extremity motor impairment. BQ 2.0 will be used for 9 weeks in conjunction with physical and occupational therapy (PT/OT) and periodic supervision (either remote or in person) of a trained site study team member. Treatments may be administered in multiple settings (e.g. acute care hospital (ACH) or inpatient rehabilitation facilities (IRF), Skilled Nursing Facility (SNF), home or other outpatient setup). The study will enroll up to 150 adult subjects who will be randomly assigned (1:1 allocation ratio) to either active or sham study intervention using BQ 2.0.

NCT ID: NCT05044286 Completed - HIV-1-infection Clinical Trials

Longer-Acting PrEP in Transgender and Gender Diverse Texans

Start date: February 1, 2022
Phase:
Study type: Observational

The long-term goal of this project is to increase uptake and adherence of LA-PrEP in TGD populations in Texas. The central hypothesis is that strategies to increase uptake of LA- PrEP that are patient centered and understand the needs of TGD people will improve uptake and adherence. The objective of this observational study is to investigate barriers, facilitators, and preferences regarding willingness and intention to use LA-PrEP in TGD populations in Texas. Data from this study will support future research on patient centered strategies for uptake and adherence of LA-PrEP in TGD populations.

NCT ID: NCT05044195 Completed - Influenza, Human Clinical Trials

A Clinical Study to Evaluate the Immunogenicity and Safety of an Adjuvanted Quadrivalent Influenza Vaccine Compared With a Licensed Quadrivalent Vaccine in Adults 50 to 64 Years of Age

Start date: September 30, 2021
Phase: Phase 3
Study type: Interventional

This Phase 3 study is a randomized, observer-blind immunogenicity and safety study of aQIV (an MF59-adjuvanted quadrivalent influenza vaccine) compared with a licensed quadrivalent influenza vaccine in adults 50 to 64 years of age.

NCT ID: NCT05044104 Completed - Healthy Clinical Trials

Wearable Technology in Endoscopy

Start date: January 11, 2022
Phase: N/A
Study type: Interventional

Researchers are assessing the accuracy and safety of wearable technology in subjects undergoing endoscopic gastrointestinal procedures with sedation.

NCT ID: NCT05043792 Completed - Healthy Clinical Trials

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Ascending Dose of TT-00920 in Healthy Subjects

Start date: August 19, 2021
Phase: Phase 1
Study type: Interventional

This is a double-blind, randomized, placebo-controlled, multiple ascending dose escalation study of TT-00920 in healthy subjects.

NCT ID: NCT05043766 Completed - Healthy Volunteers Clinical Trials

Evaluation of Oral PF614 Relative to OxyContin

Start date: September 8, 2021
Phase: Phase 1
Study type: Interventional

This is a single-center study incorporating 2 parts: A Multiple Ascending Dose Study (Part A) and a comparative Bioavailability/Bioequivalence and Food Effect study (Part B). Both parts of the study will be conducted in healthy adult subjects.