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NCT ID: NCT02080429 Not yet recruiting - Clinical trials for Management of the Second Stage of Labor in Obese Nulliparous Women by Either Passive Descent or Immediate Pushing.

Passive Descent in Obese Nulliparous Gravidae

Start date: n/a
Phase: N/A
Study type: Interventional

Obesity rates in reproductive aged women in the United States are rising. It is now universally accepted that obesity is associated with many adverse pregnancy outcomes and post-operative complications following cesarean section. Recent studies have also shown an increased rate of cesarean section in obese women, adding to the already elevated rate of complications and adverse outcomes. Given the increased a priori risk for obese patients, it is vital that the investigators reexamine management practices routinely used for normal weight women in this specific high-risk population. Passive descent has been shown to increase the spontaneous vaginal delivery rate in non-obese women; however, high quality studies have never been performed in obese women. the investigators hypothesize that passive descent could improve the spontaneous vaginal delivery rate in nulliparous, obese women with regional anesthesia. This study will randomize women to passive descent for ninety minutes or active pushing upon entry into the second stage. Further, given that passive descent is widely accepted in the midwifery literature and clinical practice, the investigators anticipate that a high-quality study in the physician literature could increase the dialogue between practitioners and lead to development of best practices in this high-risk population.

NCT ID: NCT02074293 Not yet recruiting - Clinical trials for Cervical Dystonia Adults ,

ASIS for Botox in Cervical Dystonia

ASISinCD
Start date: January 2016
Phase: Phase 1/Phase 2
Study type: Interventional

Botox acts on nerve endings, yet there are no nerve endings inside the muscle, where they are typically injected. All nerves terminate on the fascia, where ASIS device can precisely deliver Botox by creating that subdermal bloodless space, between the skin and muscle. Thus enhancing and prolonging Botox's efficacy, at the same time prevent it's unnecessary adverse reactions and distant spread, especially since Botox has no reason to travel to the rest of the body any way.

NCT ID: NCT02074163 Not yet recruiting - Clinical trials for Chronic Migraine More than15 Days Per Month, and Lasting 4 Hours a Day or Longer.

ASIS for Botox in Chronic Migraine

ASISinCM
Start date: January 2016
Phase: Phase 1/Phase 2
Study type: Interventional

Botox acts on nerve endings, yet there are no nerve endings inside the muscle, where they are typically injected. All nerves terminate on the fascia, where ASIS device can precisely deliver Botox by creating that subdermal bloodless space, between the skin and muscle. Thus enhancing and prolonging Botox's efficacy, at the same time prevent it's unnecessary adverse reactions and distant spread, especially since Botox has no reason to travel to the rest of the body any way.

NCT ID: NCT02074150 Not yet recruiting - Clinical trials for Upper Limb Spasticity Unilaterally in Adults With History of Stroke

ASIS for Botox in Upper Limb Spasticity

ASISinULS
Start date: January 2016
Phase: Phase 1/Phase 2
Study type: Interventional

Botox act on nerve endings, yet there are no nerve endings inside the muscle, where they are typically injected. All nerves terminate on the fascia, where ASIS device can precisely deliver Botox by creating that subdermal bloodless space, between the skin and muscle. Thus enhancing and prolonging Botox's efficacy, at the same time prevent it's unnecessary adverse reactions and distant spread, especially since Botox has no reason to travel to the rest of the body any way.

NCT ID: NCT02058498 Not yet recruiting - Liver Transplant Clinical Trials

Increasing Activity in Liver Transplant Patients

Start date: February 2014
Phase: N/A
Study type: Interventional

Will adult liver transplant patients who are provided with physical activity (walking) instructions increase their physical activity and perceive an improved quality of life?

NCT ID: NCT02052986 Not yet recruiting - Dyslipidemia Clinical Trials

An Open-Label Study of Vascazen in Cardiac Rehab Patients With Deficient Blood Omega-3 Fatty Acid Levels

CARE
Start date: n/a
Phase: Phase 2
Study type: Interventional

The investigators aim to test the hypothesis that dietary supplementation with VASCAZEN will correct omega-3 deficiency in cardiac rehab patients and improve biochemical risk factors.

NCT ID: NCT02045758 Not yet recruiting - Diabetes Clinical Trials

A Study to Compare Analyte Levels in Blood Samples Collected Using the TAP20-C Device With Results Obtained by Fingerstick

Start date: December 2014
Phase: N/A
Study type: Interventional

This study will compare blood collection from the forearm using an investigational device TAP20-C to blood collection from the fingertip.

NCT ID: NCT02038738 Not yet recruiting - Clinical trials for Neuroendocrine Carcinoma

68Ga-DOTATATE PET Scan Imaging in Patients With Neuroendocrine Tumors

Start date: March 2014
Phase: Phase 1/Phase 2
Study type: Interventional

Neuroendocrine cancer is an unusual disease and often goes undetected by routine imaging. The 68Ga-DOTATATE PET Scan is a novel scanning method that may have improved sensitivity and resolution specifically for neuroendocrine tumors. Patients with neuroendocrine tumors will be imaged with this agent and it will be compared to conventional imaging methods to determine the safety and efficacy of this radiopharmaceutical.

NCT ID: NCT02033070 Not yet recruiting - Barrett's Esophagus Clinical Trials

Patient Registry: Radio Frequency Ablation of Barrett's Esophagus Using HALO System

HALO
Start date: November 2013
Phase: N/A
Study type: Observational [Patient Registry]

The purpose of this study is to provide a tool for physicians to compare outcome data related to the use of the HALO Ablation Systems. This study is a single-center patient registry which will contribute to a framework for treatment and follow-up of patients with Barrett's Esophagus.

NCT ID: NCT02032589 Not yet recruiting - Multiple Sclerosis Clinical Trials

Testing the Efficacy of Self-Generation Treatment Protocol

Start date: January 2014
Phase: N/A
Study type: Interventional

Past research has shown that items self-generated by an individual, such as words or concepts, are remembered better than items that are simply read or heard. The current study seeks to demonstrate the effectiveness of using the principles of the generation effect in a treatment intervention to improve memory and functional performance in individuals with Multiple Sclerosis who have learning and memory difficulties.The main purpose of the study is to conduct an experimental investigation on the effects of a self-generation strategy treatment, embedded within practice of various activities ranging from laboratory tasks (e.g. words and concepts) to functional tasks (e.g. activities of daily living). The treatment to be tested is geared toward helping patients selfdiscover their own strengths and abilities while using self-generation to be able to utilize it independently in everyday life situations. Design: The proposed pilot study is a randomized clinical trial. Participants: Participants will include forty (40) persons with MS, between the ages of 18 and 65, who demonstrate memory impairments. Half of the participants will receive the self-generation training while learning different types of tasks (experimental group) and half of the participants (control group) will be asked to learn the same information but will receive a conventional practice (e.g. repetitions). Expected results: We expect that participants undergoing the self-generation-training intervention will show better memory performance, functional performance, quality of life, and satisfaction with treatment and life compared to participants in the control condition.