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NCT ID: NCT05493735 Completed - Clinical trials for Pelvic Organ Prolapse

Lidocaine for Pessary Check Pain Reduction

Start date: September 8, 2022
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to estimate the effect of lidocaine jelly on patient pain at the time of office pessary removal.

NCT ID: NCT05493553 Completed - Healthy Clinical Trials

Effects of an Intermittent Fasting and Dietary Supplement Regimen on Glycemic Variability

Start date: August 8, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the short-term effect of a nutritional program consisting of a yerba mate supplement, fiber supplement, and intermittent fasting on glycemic variability in men and women with risk factors for impaired fasting glucose.

NCT ID: NCT05493423 Completed - Clinical trials for End Stage Renal Disease

Confirmatory Study to Assess the V Needle in End-Stage Renal Disease Patients During In-Clinic Hemodialysis

Clinic-SAVER
Start date: November 7, 2022
Phase: N/A
Study type: Interventional

This study is a prospective, multi-center, single-arm study with subjects acting as their own control designed to confirm the safety, performance, and usability of the V Needle, a new safety needle for use during in-clinic hemodialysis that is designed to automatically generate a partial occlusion of the internal fluid path and trigger the hemodialysis machine to alarm and shut off if a complete dislodgement of the venous needle from the arm inadvertently occurs.

NCT ID: NCT05493111 Completed - Dry Eye Disease Clinical Trials

A Long-Term Safety Study Evaluating the Safety and Systemic Exposure of AR-15512

COMET-4
Start date: November 1, 2022
Phase: Phase 3
Study type: Interventional

This will be a 12-month, multicenter, vehicle-controlled, double-masked, randomized Phase 3 study conducted at approximately 10 sites in the United States. All subjects enrolled will have dry eye disease (DED). The study will consist of a Baseline (Day 1) visit as well as visits at Day 14, Day 90, Day 180, Day 270, and Day 365 (Study Exit).

NCT ID: NCT05492786 Completed - Influenza Clinical Trials

High-risk Influenza Vaccine Alert

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to assess, prospectively, the effect on flu vaccination rates of salient alerts in the electronic health record that indicate a patient's high risk for flu and its complications. The investigators hypothesize that the salient alerts will lead to increased flu vaccination compared with a standard flu alert.

NCT ID: NCT05492734 Completed - Clinical trials for Muscular Dystrophies

A Study to Assess the Feasibility of Non-invasive Dried Blood Sampling

Start date: August 12, 2022
Phase: Phase 1
Study type: Interventional

This is a Phase I, open-label, single-dose, 1-period study to compare EDG-5506 concentrations measured from venous and capillary blood sampling in healthy adult subjects. EDG-5506 is an investigational product designed to selectively modulate a fast skeletal muscle motor protein called myosin that is part of the contraction machinery of the damage-prone muscle fibers.

NCT ID: NCT05492331 Completed - Clinical trials for Intrauterine Insemination

A Study of Music Therapy to Support Intrauterine Insemination

Start date: August 3, 2022
Phase: N/A
Study type: Interventional

The purpose of this research is to learn if playing music in the room during an intrauterine insemination procedure decreases anxiety and pain for patients at the time of the procedure.

NCT ID: NCT05492253 Completed - Clinical trials for Healthy Participants

First Complementary Foods and the Infant Gastrointestinal Microbiota

Start date: January 30, 2023
Phase: N/A
Study type: Interventional

This study evaluates the effect of different complementary foods on the gastrointestinal microbiota of exclusively human milk fed infants.

NCT ID: NCT05491746 Completed - Clinical trials for Diabetic Retinopathy

Diabetic Retinopathy Tethered Augmented Reality With Eye4 Study

DRTARES
Start date: July 1, 2022
Phase: N/A
Study type: Interventional

Diabetes has reached epidemic levels in North America and with it, diabetic retinopathy is increasingly affecting the vision of millions of people. Despite treatment many patients still have vision loss that cannot be improved medically or with prescription eyeglasses. Our study is going to look at an FDA Class 1 Exempted visual aid that uses augmented reality to help people see better.

NCT ID: NCT05491733 Completed - Clinical trials for Invasive Fungal Infections

A Bioequivalence Study of APX001 High-load and Low-load Tablets

Start date: March 2, 2021
Phase: Phase 1
Study type: Interventional

A study to learn about the bioequivalence (the biochemical similarity of two medicines that share the same active ingredient and desired outcome for patients) of the study medicine called APX001 in healthy participants.